{"id":1011,"date":"2018-12-02T20:23:21","date_gmt":"2018-12-02T12:23:21","guid":{"rendered":"http:\/\/bif.nchu.edu.tw\/wordpress\/?page_id=1011"},"modified":"2024-03-15T10:30:09","modified_gmt":"2024-03-15T02:30:09","slug":"%e5%b0%88%e4%bb%bb%e5%b8%ab%e8%b3%87-2","status":"publish","type":"page","link":"https:\/\/bif.nchu.edu.tw\/wordpress\/%e5%b0%88%e4%bb%bb%e5%b8%ab%e8%b3%87-2\/","title":{"rendered":"\u5c08\u4efb\u5e2b\u8cc7"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1011\" class=\"elementor elementor-1011\">\n\t\t\t\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2aa2c657 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2aa2c657\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-183d8e11\" data-id=\"183d8e11\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3c175c53 elementor-widget elementor-widget-text-editor\" data-id=\"3c175c53\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\">\n\t\t\t\t<!-- wp:shortcode -->\n<p>\r\n\t<style type=\"text\/css\">\r\n\t\t.team-manager-free-main-area-1739 {\r\n\t\t\tdisplay: block;\r\n\t\t\toverflow: hidden;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-1739{\r\n\t\t\tbackground: #f8f8f8;\r\n\t\t\ttext-align: center;\r\n\t\t\tpadding: 0px;\r\n\t\t\twidth:100%;\r\n\t\t\theight : 100%;\r\n\t\t}\r\n\t\tdiv#team-manager-free-single-items-1739 {\r\n\t\t    display: flex;\r\n\t\t    flex-direction: row;\r\n\t\t    flex-wrap: wrap;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-pic-1739 > a {\r\n\t\t\tborder: medium none;\r\n\t\t\tbox-shadow: none !important;\r\n\t\t\toutline: medium none;\r\n\t\t\ttext-decoration: none;\r\n\t\t}\r\n\t\t\t\t\t.team-manager-free-items-style2-1739 .team-manager-free-items-style2-pic-1739 img{\r\n\t\t\t\tborder-radius: 0;\r\n\t\t\t\tbox-shadow: none;\r\n\t\t\t\theight: 220 px;\r\n\t\t\t\twidth: 100%;\r\n\t\t\t}\r\n\t\t\t\t.team-manager-free-items-style2-social_media_team-1739{\r\n\t\t\tpadding: 0px;\r\n\t\t\tmargin-bottom: 0 !important;\r\n\t\t\tlist-style: none;\r\n\t\t\ttext-align: center;\r\n\t\t\tbackground: #c1c1c1;\r\n\t\t\tmargin:0px;\r\n\t\t\tpadding: 0px 20px;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-social_media_team-1739 > li{\r\n\t\t\tdisplay: inline-block;\r\n\t\t\tmargin-bottom: 0px;\r\n\t\t\tmargin-right: 5px;\r\n\t\t\tmargin-top: 0px;\r\n\t\t\tpadding: 8px 0px;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-social_media_team-1739 > li > a{\r\n\t\t\tbackground: #31aab5 none repeat scroll 0 0;\r\n\t\t\tborder-radius: 50%;\r\n\t\t\tbox-shadow: none;\r\n\t\t\tcolor: #fff;\r\n\t\t\tdisplay: block;\r\n\t\t\theight: 30px;\r\n\t\t\tline-height: 30px;\r\n\t\t\ttransition: all 0.3s ease 0s;\r\n\t\t\twidth: 30px;\r\n\t\t\ttext-decoration: none !important;\r\n\t\t    box-shadow: none;\r\n\t\t    outline: none;\r\n\t\t\tborder:none;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-social_media_team-1739 > li > a:hover{\r\n\t\t\tbackground: #fff none repeat scroll 0 0;\r\n\t\t\tborder: medium none;\r\n\t\t\tbox-shadow: none;\r\n\t\t\tcolor: #31aab5;\r\n\t\t\toutline: medium none;\r\n\t\t\ttext-decoration: none;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-teamprofiles-1739 .team-manager-free-items-style2-team-title-1739{\r\n\t\t\tmargin-bottom: 0px;\r\n\t\t\tmargin-top: 0px !important;\r\n\t\t\tpadding:10px 15px;\r\n\t\t\tborder-bottom: 1px solid #ddd;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-teamprofiles-1739 .team-manager-free-items-style2-team-title-1739 a{\r\n\t\t\tbox-shadow: none;\r\n\t\t\tcolor: #007acc;\r\n\t\t\tfont-size: 20px;\r\n\t\t\tletter-spacing: 1px;\r\n\t\t\toutline: medium none;\r\n\t\t\ttext-decoration: none;\r\n\t\t\ttext-transform: unset;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-teamprofiles-1739 .team-manager-free-items-style2-team-title-1739 a:hover{\r\n\t\t\ttext-decoration:none;\r\n\t\t\tcolor:#333333;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-teamprofiles-1739 .team-manager-free-items-style2-team-post-1739{\r\n\t\t\tborder-bottom: 1px solid #ddd;\r\n\t\t\tdisplay: block;\r\n\t\t\tpadding: 10px 15px;\r\n\t\t\tfont-size: 15px;\r\n\t\t\tfont-style: italic;\r\n\t\t\tcolor:#333333;\r\n\t\t\tletter-spacing: 0.5px;\r\n\t\t}\r\n\t\t.team-manager-free-items-style2-teamprofiles-1739 .team-manager-free-items-style2-team-description-1739{\r\n\t\t\tfont-size: 14px;\r\n\t\t\tfont-weight: 400;\r\n\t\t\tline-height: 23px;\r\n\t\t\tcolor:#000000;\r\n\t\t    padding: 15px;\r\n\t\t    margin-bottom: 0px;\r\n\t\t}\r\n\t\t@media screen and (max-width: 990px){\r\n\t\t\t.team-manager-free-items-style2-1739{\r\n\t\t\t\tmargin-bottom: 30px;\r\n\t\t\t}\r\n\t\t}\r\n\t\t\r\n\t\t.lightbox { display: none; }\r\n\r\n\t\t.team_popup_container-1739 {\r\n\t\t\tdisplay: block;\r\n\t\t\toverflow: hidden;\r\n\t\t}\r\n\t\t.team_popup_left_side_area-1739 {\r\n\t\t\tdisplay: block;\r\n\t\t\tfloat: left;\r\n\t\t\theight: auto;\r\n\t\t\tmargin-right: 50px;\r\n\t\t\tmargin-top: 3px;\r\n\t\t\twidth: 300px;\r\n\t\t\toverflow: hidden;\r\n\t\t}\r\n\t\t.team_popup_container-1739 h2 {\r\n\t\t\tdisplay: block;\r\n\t\t\tmargin: 0px 0px 20px;\r\n\t\t\toverflow: hidden;\r\n\t\t\tfont-size: 30px;\r\n\t\t\tfont-weight: 600;\r\n\t\t}\r\n\t\t.team_popup_right_side_area-1739 {\r\n\t\t  margin-top: 0px;\r\n\t\t  display: block;\r\n\t\t  overflow: hidden;\r\n\t\t}\r\n\t\t.team_popup_right_side_area-1739 p {\r\n\t\t  line-height: 28px;\r\n\t\t  font-size: 15px;\r\n\t\t}\r\n\t\t.team_popup_left_side_area_img-1739 > img {\r\n\t\t  display: block;\r\n\t\t  width: 300px;\r\n\t\t  overflow: hidden;\r\n\t\t}\r\n\t\t.team-manager-popup-items-social-1739{\r\n\t\t\tpadding:0;\r\n\t\t\tmargin:0;\r\n\t\t\tlist-style:none;\r\n\t\t}\r\n\t\t.team-manager-popup-items-social-1739 li{\r\n\t\t\tdisplay:inline-block;\r\n\t\t}\r\n\t\t.team-manager-popup-items-social-1739 li a{\r\n\t\t\tbackground: #fff none repeat scroll 0 0;\r\n\t\t\tborder: 1px solid #fff;\r\n\t\t\ttext-decoration: none !important;\r\n\t\t    box-shadow: none;\r\n\t\t    outline: none;\r\n\t\t\tcolor: #da3e65;\r\n\t\t\ttransition: all 0.3s ease 0s;\r\n\t\t\tmargin-right:10px;\r\n\t\t}\r\n\t\t.team-manager-popup-items-social-1739 li a:hover{\r\n\t\t\ttext-decoration:none;\r\n\t\t\tcolor:#333;\r\n\t\t}\r\n\t\t.team_popup_contact_area-1739{\r\n\t\t\tdisplay: block;\r\n\t\t\toverflow : hidden;\r\n\t\t\ttext-align: center;\r\n\t\t\tmargin: 15px 0px;\r\n\t\t\tline-height: 25px;\r\n\t\t}\r\n\t\t.team_popup_contact_area-1739 span.cemail {\r\n\t\t  display: block;\r\n\t\t  overflow: hidden;\r\n\t\t  text-align: left;\r\n\t\t}\r\n\t\t.team_popup_contact_area-1739 span.cemail a{\r\n\t\t  outline: none;\r\n\t\t  text-decoration: none;\r\n\t\t  box-shadow: none;\r\n\t\t  color:#333;\r\n\t\t}\r\n\r\n\t\t\/* Tablet Layout: 768px. *\/\r\n\t\t@media only screen and (min-width: 768px) and (max-width: 991px) { \r\n\t\t\t.featherlight .featherlight-content {\r\n\t\t\t    margin-left: 30px;\r\n\t\t\t    margin-right: 30px;\r\n\t\t\t    max-height: 98%;\r\n\t\t\t    padding: 10px 10px 0;\r\n\t\t\t    border-bottom: 10px solid transparent;\r\n\t\t\t}\r\n\t\t}\r\n\r\n\r\n\t\t\/* Wide Mobile Layout: 480px. *\/\r\n\t\t@media only screen and (min-width: 480px) and (max-width: 767px) {\r\n\t\t\t.team-manager-free-items-style2-1739 .team-manager-free-items-style2-pic-1739 img{\r\n\t\t\t\tborder-radius: 0;\r\n\t\t\t\tbox-shadow: none;\r\n\t\t\t\theight: auto;\r\n\t\t\t\twidth: 100%;\r\n\t\t\t}\r\n\t\t\t.team_popup_left_side_area-1739 {\r\n\t\t\t    display: block;\r\n\t\t\t    float: none;\r\n\t\t\t    height: auto;\r\n\t\t\t    margin-right: 50px;\r\n\t\t\t    width: 100%;\r\n\t\t\t    overflow: hidden;\r\n\t\t\t}\r\n\t\t\t.featherlight .featherlight-content {\r\n\t\t\t    margin-left: 30px;\r\n\t\t\t    margin-right: 30px;\r\n\t\t\t    max-height: 98%;\r\n\t\t\t    padding: 10px 10px 0;\r\n\t\t\t    border-bottom: 10px solid transparent;\r\n\t\t\t}\r\n\t\t\t.team_popup_left_side_area_img-1739 > img {\r\n\t\t\t    display: block;\r\n\t\t\t    width: 100%;\r\n\t\t\t    overflow: hidden;\r\n\t\t\t    height: 100%;\r\n\t\t\t}\r\n\t\t}\r\n\r\n\t\t\/* XS Portrait *\/\r\n\t\t@media (max-width: 479px) {\r\n\t\t\t.team-manager-free-items-style2-1739 .team-manager-free-items-style2-pic-1739 img{\r\n\t\t\t\tborder-radius: 0;\r\n\t\t\t\tbox-shadow: none;\r\n\t\t\t\theight: auto;\r\n\t\t\t\twidth: 100%;\r\n\t\t\t}\r\n\t\t\t.team_popup_left_side_area-1739 {\r\n\t\t\t    display: block;\r\n\t\t\t    float: none;\r\n\t\t\t    height: auto;\r\n\t\t\t    margin-right: 50px;\r\n\t\t\t    margin-top: 3px;\r\n\t\t\t    width: 100%;\r\n\t\t\t    overflow: hidden;\r\n\t\t\t}\r\n\t\t\t.featherlight .featherlight-content {\r\n\t\t\t    margin-left: 30px;\r\n\t\t\t    margin-right: 30px;\r\n\t\t\t    max-height: 98%;\r\n\t\t\t    padding: 10px 10px 0;\r\n\t\t\t    border-bottom: 10px solid transparent;\r\n\t\t\t}\r\n\t\t\t.team_popup_left_side_area_img-1739 > img {\r\n\t\t\t    display: block;\r\n\t\t\t    width: 100%;\r\n\t\t\t    overflow: hidden;\r\n\t\t\t    height: 100%;\r\n\t\t\t}\r\n\t\t}\r\n\t<\/style>\r\n\r\n\r\n\r\n\t<div class=\"team-manager-free-main-area-1739\">\r\n\t\t<div id=\"team-manager-free-single-items-1739\">\r\n\t\t\t\r\n\t\t\t\t<div class=\"teamshowcasefree-col-lg-3 teamshowcasefree-col-md-2 teamshowcasefree-col-sm-2 teamshowcasefree-col-xs-1\">\r\n\t\t\t\t\t<div class=\"team-manager-free-items-style2-1739\">\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-pic-1739\">\r\n\t\t\t\t\t\t\t<a href=\"#\" data-featherlight=\"#fl1292240553\">\r\n\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_HouMingHong_new.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t<div class=\"lightbox\" id=\"fl1292240553\">\r\n\t\t\t\t\t\t\t\t\t<div class=\"team_popup_container-1739\">\r\n\t\t\t\t\t\t\t\t\t\t<h2>\u4faf\u660e\u5b8f<\/h2>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area_img-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_HouMingHong_new.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_contact_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\"><a href=\"mailto:mhho@dragon.nchu.edu.tw\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\tmhho@dragon.nchu.edu.tw<\/a><\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">(04)22840338 #7011(\u8fa6\u516c\u5ba4) #7121(\u5be6\u9a57\u5ba4)<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">\u52d5\u690d\u7269\u9632\u6aa2\u75ab\u5927\u6a137\u6a13701\u5ba4<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<ul class=\"team-manager-popup-items-social-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_right_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<h4><a href=\"https:\/\/orcid.org\/0000-0003-4170-1527\"><img loading=\"lazy\" class=\"wp-image-2595 alignright\" src=\"http:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png\" alt=\"\" width=\"80\" height=\"80\" srcset=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png 150w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-24x24.png 24w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-36x36.png 36w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-48x48.png 48w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948.png 190w\" sizes=\"(max-width: 80px) 100vw, 80px\" \/><\/a>\u7814\u7a76\u5ba4 \uff1a <a href=\"https:\/\/mhholab712.wixsite.com\/mhholab\">\u85e5\u7269\u8a2d\u8a08\u53ca\u5316\u5b78\u751f\u7269\u6838\u5fc3\u5be6\u9a57\u5ba4<\/a><\/h4>\n<h4>\u7c21\u8981\u7d93\u6b77<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"20%\">\u8077\u7a31<\/th>\n<th width=\"54%\">\u670d\u52d9\u55ae\u4f4d<\/th>\n<th width=\"26%\">\u8d77\u8a16\u5e74\u6708<\/th>\n<\/tr>\n<tr>\n<td>\u4e3b\u4efb<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3<\/td>\n<td>2023.08\u2013\u8fc4\u4eca<\/td>\n<\/tr>\n<tr>\n<td>\u526f\u9662\u9577<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u547d\u79d1\u5b78\u9662<\/td>\n<td>2022.08\u20132023.08<\/td>\n<\/tr>\n<tr>\n<td>\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240<\/td>\n<td>2013.08\u2013\u8fc4\u4eca<\/td>\n<\/tr>\n<tr>\n<td>\u526f\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240<\/td>\n<td>2010.02\u2013 2013.07<\/td>\n<\/tr>\n<tr>\n<td>\u517c\u4efb\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u7814\u7a76\u6240<\/td>\n<td>2008.8-2010.01<\/td>\n<\/tr>\n<tr>\n<td>\u5408\u8058\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u547d\u79d1\u5b78\u7cfb<\/td>\n<td>2008.8-2010.01<\/td>\n<\/tr>\n<tr>\n<td>\u5408\u8058\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3<\/td>\n<td>2008.8-2010.01<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2008.08 \u2013 2010.01<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78\u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3<\/td>\n<td>2007.02-2008.07<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u5be6\u8e10\u5927\u5b78\u98df\u54c1\u71df\u990a\u8207\u4fdd\u5065\u751f\u6280\u5b78\u7cfb<\/td>\n<td>2004.8-2007.1<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb\u5f8c\u7814\u7a76\u54e1<\/td>\n<td>\u4e2d\u592e\u7814\u7a76\u9662\u751f\u7269\u5316\u5b78\u6240<\/td>\n<td>2003.8-2004.7<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb<\/td>\n<td>\u570b\u7acb\u53f0\u7063\u5927\u5b78\u751f\u5316\u79d1\u5b78\u6240<\/td>\n<td>1999.09-2003.07<\/td>\n<\/tr>\n<tr>\n<td>\u78a9\u58eb<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u751f\u7269\u5316\u5b78\u6240<\/td>\n<td>1997.09-1999.07<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u69ae\u8b7d\uff1a<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u540d\u7a31<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>\u4e2d\u8208\u5927\u5b78\u512a\u79c0\u9752\u5e74\u6559\u5e2b\u734e(2010\u548c 2012\u5e74)<\/li>\n<li>\u4e2d\u8208\u5927\u5b78\u7814\u7a76\u7e3e\u512a\u734e (2013\u5e74)<\/li>\n<li>\u8cc7\u6df1\u512a\u826f\u6559\u5e2b (2014\u5e74)<\/li>\n<li>\u7279\u8058\u6559\u6388(2015\u5e74)<\/li>\n<li>\u5091\u51fa\u4eba\u624d\u767c\u5c55\u57fa\u91d1\u6703\u7b2c\u4e09\u5c46\u5e74\u8f15\u5b78\u8005\u5275\u65b0\u734e(2015\u5e74)<\/li>\n<li>104\u5e74\u5ea6\u300c\u5091\u51fa\u5316\u5b78\u5bb6\u9752\u5e74\u734e\u300d(2015\u5e74)<\/li>\n<li>\u7b2c11\u5c46\u6c38\u4fe1\u674e\u5929\u5fb7\u9752\u5e74\u91ab\u85e5\u79d1\u6280\u734e(2015\u5e74)<\/li>\n<li>\u672c\u6821108\u5e74\u5ea6\u300c\u512a\u79c0\u5e74\u8f15\u5b78\u8005\u61f7\u74a7\u734e\u300d(2019\u5e74)<\/li>\n<li>\u69ae\u73722020\u300c\u570b\u5bb6\u65b0\u5275\u734e\u300d(2020\u5e74)<\/li>\n<li>\u69ae\u7372109\u5e74\u5ea6\u79d1\u6280\u90e8\u5091\u51fa\u734e(2021\u5e74)<\/li>\n<li>\u69ae\u73722022\u5e74\u5ea6\u300c\u570b\u5bb6\u65b0\u5275\u7cbe\u9032\u734e\u300d<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u5b78\u8207\u7814\u7a76<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u7a76\u65b9\u5411<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>\u86cb\u767d\u8cea\u5de5\u7a0b<\/li>\n<li>\u7d50\u69cb\u751f\u7269<\/li>\n<li>\u85e5\u7269\u8a2d\u8a08<\/li>\n<li>\u751f\u7269\u7269\u7406<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u6388\u8ab2\u7a0b:<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u8ab2\u7a0b\u540d\u7a31<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\n<p class=\"pHead\">\u907a\u50b3\u5b78(\u751f\u79d1\u7cfb)\u3001\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u751f\u79d1\u7cfb)\u3001\u86cb\u767d\u8cea\u5de5\u7a0b\u5b78(\u57fa\u8cc7\u6240)\u3001\u7d50\u69cb\u751f\u7269\u8cc7\u8a0a\u5b78(\u57fa\u8cc7\u6240)\u3001\u751f\u7269\u6280\u8853\u7279\u8ad6(\u751f\u6280\u535a)\u3001\u61c9\u7528\u57fa\u56e0\u9ad4\u5b78\u53ca\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u57fa\u8cc7\u6240)\u3001\u751f\u7269\u5316\u5b78\u7279\u8ad6(\u751f\u6280\u535a)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u7814\u7a76\u4e3b\u984c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5be6\u9a57\u5ba4\u7814\u7a76\u65b9\u5411<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\u6838\u9178\u7d50\u5408\u6297\u764c\u85e5\u7269\u6a5f\u5236\u4e4b\u63a2\u8a0e<\/p>\n<p>\u51a0\u72c0\u75c5\u6bd2\u4e4b\u6838\u6bbc\u86cb\u767d\u529f\u80fd\u548c\u7d50\u69cb\u63a2\u8a0e<\/p>\n<p>\u6297\u75c5\u6bd2\u85e5\u7269\u958b\u767c<\/p>\n<p>&nbsp;<\/p>\n<p>\u672c\u5be6\u9a57\u5ba4\u4e4b\u7814\u7a76\u9818\u57df\u4e3b\u8981\u5206\u70ba\u5169\u500b\u90e8\u4efd\uff1a(1) \u611f\u5192\u75c5\u6bd2(HCoV-229E\u3001HCoV-OC43\u8207H1N1)\u4e4b\u6838\u6bbc\u86cb\u767d\u8207\u6838\u9178\u7d50\u5408\u529f\u80fd\u548c\u7d50\u69cb\u63a2\u8a0e\uff1b(2)\u6297\u764c\u85e5\u7269\u4e4b\u7814\u767c\u8207\u6297\u764c\u6a5f\u5236\u4e4b\u63a2\u8a0e\uff0c\u5206\u8ff0\u5982\u4e0b\uff1a<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\"><span class=\"Span-Title\">1. \u611f\u5192\u75c5\u6bd2\u4e4b\u6838\u6bbc\u86cb\u767d\u8207\u6838\u9178\u7d50\u5408\u529f\u80fd\u548c\u7d50\u69cb\u63a2\u8a0e:<\/span><\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\"><span class=\"Span-Title\">\u51a0\u72c0\u75c5\u6bd2\u4e4b\u6838\u6bbc\u86cb\u767d\u8207\u6838\u9178\u7d50\u5408\u529f\u80fd\u548c\u7d50\u69cb\u4e4b\u63a2\u8a0e<\/span><\/p>\n<p>\u81ea\u5f9e2002\u5e74\u51ac\u52302003\u5e74\u6625\uff0cSARS\u51a0\u72c0\u75c5\u6bd2\u8086\u8650\u5168\u7403\uff0c\u4e26\u9020\u6210\u56b4\u91cd\u6025\u6027\u547c\u5438\u9053\u75c7\u5019\u7fa4(Severe Acute Respiratory Syndrome\uff0cSARS)\uff0c\u6b64\u6642\u5168\u4e16\u754c\u518d\u6b21\u8208\u8d77\u51a0\u72c0\u75c5\u6bd2\u7684\u7814\u7a76\u98a8\u6f6e\u3002\u4f9d\u7167\u8840\u6e05\u5b78\u5206\u6790\uff0c\u4eba\u985e\u51a0\u72c0\u75c5\u6bd2229E\u53caOC43\u5206\u5c6c\u65bc\u51a0\u72c0\u75c5\u6bd2\u4e4b\u7b2c\u4e00\u7fa4\u7d44\u548c\u7b2c\u4e8c\u7fa4\u7d44\uff0c\u6b64\u4e8c\u7a2e\u75c5\u6bd2\u4e3b\u8981\u6703\u5f15\u8d77\u4eba\u985e\u6025\u6027\u4e0a\u547c\u5438\u9053\u611f\u67d3\uff0c\u70ba\u4e00\u822c\u4eba\u985e\u666e\u901a\u611f\u5192\u4e4b\u4e3b\u8981\u81f4\u75c5\u539f\u3002\u4eba\u985e\u51a0\u72c0\u75c5\u6bd2229E\u53caOC43\u4e4b\u6838\u6bbc\u86cb\u767d(nucleocapsid protein)\u70ba\u75c5\u6bd2\u4e3b\u8981\u7d50\u69cb\u86cb\u767d\u4e4b\u4e00\uff0c\u70ba\u4e00\u500b\u9ad8\u96fb\u8377\u3001\u9ad8\u89aa\u6c34\u6027\u7684\u9e7c\u6027\u86cb\u767d\u8cea\u3002\u6b64\u7a2e\u86cb\u767d\u7684\u4e3b\u8981\u529f\u80fd\u662f\u8207\u75c5\u6bd2RNA\u7d50\u5408\uff0c\u4e26\u5f62\u6210\u87ba\u65cb\u72c0\u7684\u6838\u6bbc\u7d50\u69cb(nucleocapsid structure)\uff0c\u9032\u4e00\u6b65\u7d44\u6210\u6838\u91a3\u6838\u6bbc\u86cb\u767d\u8907\u5408\u9ad4(ribonucleoprotein\uff0cRNP)\u800c\u5f62\u6210\u75c5\u6bd2\u7684\u6838\u5fc3\uff0c\u4f7f\u75c5\u6bd2RNA\u5728\u6046\u5b9a\u7684\u69cb\u5f62\u4e0b\u9032\u884c\u8907\u88fd\u8207\u8f49\u9304\u3002\u622a\u81f3\u76ee\u524d\u70ba\u6b62\uff0c\u9084\u6c92\u6709\u4efb\u4f55\u6587\u737b\u662f\u91dd\u5c0d\u4eba\u985e\u51a0\u72c0\u75c5\u6bd2229E\u548cOC43\u6838\u6bbc\u86cb\u767d\u4e4b\u751f\u7269\u5316\u5b78\u53ca\u751f\u7269\u7269\u7406\u7684\u7279\u6027\u4f86\u9032\u884c\u7814\u7a76\u3002\u7d93\u904e\u5e8f\u5217\u6bd4\u5c0d\u5f8c\u767c\u73fe\uff0c\u51a0\u72c0\u75c5\u6bd2\u4e4b\u6838\u6bbc\u86cb\u767d\u96d6\u5177\u6709\u4e9b\u8a31\u4fdd\u7559\u7aef\uff0c\u4f46\u5f7c\u6b64\u9593\u7684\u76f8\u4f3c\u6027\u537b\u4e0d\u9ad8\uff0c\u56e0\u6b64\u63a8\u6e2c\u51a0\u72c0\u75c5\u6bd2\u6838\u6bbc\u86cb\u767d\u4e4b\u751f\u7269\u5316\u5b78\u53ca\u751f\u7269\u7269\u7406\u7684\u7279\u6027\u4e5f\u6703\u6709\u6240\u4e0d\u540c\u3002\u672c\u5be6\u9a57\u5ba4\u4e3b\u8981\u662f\u91dd\u5c0d\u4eba\u985e\u51a0\u72c0\u75c5\u6bd2229E\u548cOC43\u6838\u6bbc\u86cb\u767d\u4e4b\u751f\u7269\u5316\u5b78\u3001\u751f\u7269\u7269\u7406\u53ca\u514d\u75ab\u5b78\u7684\u7279\u6027\u9032\u884c\u4e00\u4e9b\u91cd\u8981\u7684\u7814\u7a76\uff0c\u8a08\u5283\u7684\u7d50\u679c\u4e5f\u5c07\u6703\u5c0d\u65bc\u85e5\u7269\u3001\u75ab\u82d7\u53ca\u8a3a\u65b7\u65b9\u6cd5\u7684\u958b\u767c\u6709\u76f8\u7576\u5927\u7684\u5e6b\u52a9\u3002<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\"><span class=\"Span-Title\">A\u578b\u6d41\u611f\u75c5\u6bd2H1N1\u6838\u6bbc\u86cb\u767d\u4e4b\u7a69\u5b9a\u6027\u53ca\u5176\u6838\u9178\u7d50\u5408\u529f\u80fd\u8207\u7d50\u69cb\u4e4b\u63a2\u8a0e<\/span><\/p>\n<p>\u6d41\u611f\u75c5\u6bd2\u5728\u5206\u985e\u5b78\u4e0a\u5c6c\u65bc\u6b63\u9ecf\u6db2\u75c5\u6bd2\u79d1(Orthomyxoviridae)\uff0c\u5206\u70baA\u3001B\u3001C\u4e09\u578b\u3002\u5176\u4e2d\u4eba\u985e\u5e38\u898b\u7684A\u578b\u6d41\u611f\u75c5\u6bd2\u6709\u897f\u73ed\u7259\u6d41\u611f(H1N1)\u3001\u4e9e\u6d32\u6d41\u611f(H2N2)\u8207\u9999\u6e2f\u6d41\u611f(H3N2)\uff0c\u672c\u5be6\u9a57\u5ba4\u4ee5A\u578b\u6d41\u611f\u75c5\u6bd2H1N1\u4f5c\u70ba\u7814\u7a76\u7684\u75c5\u6bd2\u682a\uff0c\u4f86\u4e86\u89e3\u5176\u6838\u6bbc\u86cb\u767d\u4e4b\u7279\u6027\u3002H1N1\u6838\u6bbc\u86cb\u767d(nucleoprotein)\u5206\u5b50\u91cf\u70ba56kDa\uff0c\u6703\u7d50\u5408\u5230\u75c5\u6bd2\u7684genome RNA\uff0c\u5f9eribonucleoprotein(RNP)\u8907\u5408\u7269\u8d77\u7d04\u9593\u969420\u500bnucleotides\u3002\u6d41\u611f\u75c5\u6bd2\u4e4b\u6838\u6bbc\u86cb\u767d\u4e3b\u8981\u7684\u529f\u80fd\u662f\u5305\u88f9\u75c5\u6bd2\u7684\u6838\u9178\uff0c\u4e26\u4e14\u5728\u75c5\u6bd2\u7684\u589e\u751f\u7684\u904e\u7a0b\u4e2d\u626e\u6f14\u8abf\u7bc0\u7684\u89d2\u8272\uff0c\u5176\u4e2d\u5305\u62ec\u8907\u88fd(replication)\u3001\u8f49\u9304(transcription)\u3001\u5305\u88dd(packaging)\u8207\u75c5\u6bd2\u7684\u6210\u719f(maturation)\u3002\u6b64\u5916\uff0c\u6838\u6bbc\u86cb\u767d\u4e5f\u6703\u8207\u611f\u67d3\u7d30\u80de\u7684\u86cb\u767d\u7522\u751f\u4ea4\u4e92\u4f5c\u7528\uff0c\u5305\u62ecactin\u3001nuclear import components\u3001export apparatus\u8207nuclear RNA helicase\u3002\u672c\u5be6\u9a57\u5ba4\u4e3b\u8981\u91dd\u5c0dH1N1\u6838\u6bbc\u86cb\u767d\u9032\u884c\u751f\u7269\u5316\u5b78\u8207\u751f\u7269\u7269\u7406\u65b9\u9762\u4e4b\u76f8\u95dc\u7814\u7a76\uff0c\u4ee5\u89e3\u958b\u5176\u7d50\u69cb\u8207\u529f\u80fd\u7684\u5967\u79d8\u3002<\/td>\n<\/tr>\n<tr>\n<td class=\"topic\">\n<p class=\"pHead\"><span class=\"Span-Title\">2. \u6838\u9178\u7d50\u5408\u4e4b\u6297\u764c\u85e5\u7269\u7814\u767c\u8207\u6297\u764c\u6a5f\u5236\u63a2\u8a0e:<\/span><\/p>\n<p>\u672c\u7814\u7a76\u984c\u76ee\u4e3b\u8981\u662f\u4ee5\u6297\u764c\u85e5\u8207\u76ee\u6a19\u7269\u7684\u7d50\u5408\u6a5f\u5236\u53ca\u5176\u5728\u764c\u75c7\u75be\u75c5\u7684\u6cbb\u7642\u4f5c\u4e00\u7cfb\u5217\u7684\u63a2\u8a0e\u3002\u6297\u751f\u7d20Mithramycin \u548cChromomycin A3 \u662f\u4e00\u7a2e\u9375\u7d50\u65bcDNA\u7684aureolic \u985e\u6297\u764c\u85e5\u7269\u3002 \u5176\u6d3b\u6027\u4e3b\u8981\u4f86\u81ea\u65bc\u5e72\u64feDNA\u7684\u8907\u88fd\u53ca\u8f49\u9304\u4f5c\u7528\uff0c\u4e26\u904b\u7528\u65bc\u81e8\u5e8a\u7684\u764c\u75c7\u6cbb\u7642\u4e0a\u3002\u6b64\u985e\u85e5\u7269\u85c9\u7531\u55ae\u4e00\u7684\u4e8c\u50f9\u91d1\u5c6c\u96e2\u5b50\u9375\u7d50\u65bc\u5bcc\u542bG\/C\u7684DNA\u96d9\u87ba\u65cb\u5e8f\u5217\u7d44\u6210\u7684\u6b21\u6e9d(minor groove)\u4e0a\uff0c\u800c\u660e\u986f\u4f7f\u6b21\u6e9d\u8b8a\u5f97\u6bd4\u5148\u524d\u5bec\u95ca\u3002\u5728\u4e4b\u524d\u7684\u7814\u7a76\u8b49\u5be6\uff0c\u7576\u6c92\u6709DNA\u7684\u60c5\u6cc1\u4e0b\uff0c\u4e8c\u50f9\u91d1\u5c6c\u96e2\u5b50\u53ef\u4ee5\u5f62\u6210\u91d1\u5c6c\u96e2\u5b50aureolic \u985e\u85e5\u7269\u805a\u5408\u9ad4\u3002\u73fe\u4eca\u6709\u8a31\u591a\u7684\u6297\u764c\u85e5\u7269\u6703\u5229\u7528\u91d1\u5c6c\u96e2\u5b50\u6240\u7d50\u5408\u884c\u6210\u7684\u8907\u5408\u7269\u800c\u5c0e\u81f4\u764c\u7d30\u80de\u7684\u6b7b\u4ea1\uff0c\u53ef\u4ee5\u589e\u52a0\u5176\u61c9\u7528\u5728\u4eba\u985e\u60e1\u6027\u816b\u7624\u6cbb\u7642\u7684\u6f5b\u529b\u3002\u56e0\u6b64\u672c\u8a08\u5283\u6211\u5011\u5c07\u7814\u7a76aureolic\u985e\u6297\u764c\u85e5\u7269\u8207\u5176\u4ed6\u4e0d\u540c\u91d1\u5c6c\u96e2\u5b50\u69cb\u6210\u8907\u5408\u7269\u7684\u80fd\u529b(\u7d50\u5408\u529b\u548c\u76f8\u5c0d\u914d\u4f4d)\uff0c\u4e26\u4e14\u8a55\u4f30\u6b64\u985e\u805a\u5408\u7269\u7684\u751f\u5316\u529f\u80fd\u3001\u6291\u5236topoisomerase I\u53ca\u7d30\u80de\u6bd2\u6027\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u8457\u4f5c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u671f\u520a\u8ad6\u6587(*Corresponding author)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li style=\"list-style-type: none;\">\n<ol class=\"Exp\">\n<li>Jhen-Yi Hong, Shih-Chao Lin, Kylene Kehn-Hall, Kai-Min Zhang, Shun-Yuan Luo, Hung-Yi Wu, Sui-Yuan Chang, and Ming-Hon Hou* (January 2024) Targeting protein\u2013protein interaction interfaces with anti-viral N protein inhibitor in SARS-CoV-2, Biophysical Journal<\/li>\n<li>Shun-Ching Wang, Yi-Tsao Chen, Roshan Satange, Jhih-Wei Chu* and Ming-Hon Hou* (May 2023) Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1. Journal of Biological Chemistry<\/li>\n<li>Kuo-Yang Huang, Ying-Lin Hsu, Huang-Chi Chen, Ming-Hwarng Horng, Cheliang Chung, Ching-Hsiung Lin, Jia-Lang Xu* and Ming-Hon Hou* (May 2023) Developing a machine-learning model for real-time prediction of successful extubation in mechanically ventilated patients using time-series ventilator-derived parameters. Frontiers in Medicine, Volume 10 &#8211; 2023<\/li>\n<li>Roshan Satange, Peng Jin, Ming-Hon Hou, Ambadas B. Rode* (April 2023) Editorial: Non-canonical nucleic acid structures, functions and their applications for understanding human genetic diseases. Frontiers in Genetics, 14:1188978<\/li>\n<li>Roshan Satange, Chih-Chun Chang, Long\u2010Yuan Li, Sheng-Hao Lin, Stephen Neidle*, and Ming-Hon Hou* (March 2023) Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects. Nucleic Acids Research, volume 51, Issue 8, pages 3540\u20133555<\/li>\n<li>Roshan Satange, Ambadas B. Rode, and Ming-Hon Hou* (Nov 2022) Revisiting recent unusual drug-DNA complex structures: implications for cancer and neurological disease diagnostics and therapeutics. Bioorganic &amp; Medicinal Chemistry, volume 76, 2022, 117094<\/li>\n<li>Roshan Satange, Shih-Hao Kao, Ching-Ming Chien, Shan-Ho Chou, Chi-Chien Lin, Stephen Neidle*, and Ming-Hon Hou* (July 2022) Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism. Nucleic Acids Research, volume 50, issue 15, p.8867-8881<\/li>\n<li>Jia-Ning Hsu, Jyun-Siao Chen, Shan-Meng Lin, Yi-Jheng Chen, Jhen-Yi Hong, U-Ser Jeng, Shun-Yuan Luo*, and Ming-Hon Hou* (April 2022) Targeting the N-terminus domain of the coronavirus nucleocapsid protein induces abnormal oligomerization via allosteric modulation. Frontiers in Molecular Biosciences, Volume 9, Article 871499, 2022<\/li>\n<li>Chun-Wei Lin, Kuo-Yang Huang, Ching-Hsiung Lin, Bing-Yen Wang, Chew-Teng Kor, Ming-Hon Hou, and Sheng-Hao Lin* (Feb 2022) Video-Assisted Thoracoscopic Surgery in Community-Acquired Thoracic Empyema: Analysis of Risk Factors for Mortality. Surgical Infections Vol. 23, No. 2. 191-198<\/li>\n<li>Tai-Lin Chen, Anilkumar S. Patel, Vicky Jain, Ramajayam Kuppusamy, Yi-Wen Lin, Ming-Hon Hou, Tsann-Long Su*, and Te-Chang Lee* (August 2021) Discovery of Oral Anticancer 1,2-Bis(hydroxymethyl)benzo[g]pyrrolo[2,1-a]phthalazine Hybrids That Inhibit Angiogenesis and Induce DNA Cross-Links. Journal of Medicinal Chemistry<\/li>\n<li>Chung-ke Chang, Shan-Meng Lin, Roshan Satange, Shih-Chao Lin, Sin-Cih Sun, Hung-Yi Wu, Kylene Kehn-Hall and Ming-Hon Hou* (April 2021) Targeting protein-protein interaction interfaces in COVID-19 drug discovery. Computational and Structural Biotechnology Journal, volume 19, 2246-2255<\/li>\n<li>Cyong-Ru Jhan, Roshan Satange, Shun-Ching Wang, Jing-Yi Zeng, Yih-Chern Horng, Peng Jin, Stephen Neidle, and Ming-Hon Hou* (April 2021) Targeting the ALS\/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction. Nucleic Acids Research, Volume 49, issue 16, p.9526-9538<\/li>\n<li>Ching-Ming Chien, Pei-Ching Wu, Roshan Satange, Cheng-Chun Chang, ZI-Lun Lai, Lauren D. Hagler, Steven C. Zimmerman, and\u00a0Ming-Hon Hou*.\u00a0(June\u00a02020)\u00a0Structural basis for targeting T:T mismatch with triaminotriazine-acridine conjugate induces a U-shaped head-to-head four-way junction in CTG repeat DNA.\u00a0Journal of the American Chemical Society<\/li>\n<li>Shan-Meng Lin, Shih-Chao Lin, Jia-Ning Hsu, Chung-ke Chang, Ching-Ming Chien, Yong-Sheng Wang, Hung-Yi Wu, U-Ser Jeng, Kylene Kehn-Hall\u00a0and\u00a0Ming-Hon Hou*.\u00a0(Feb 2020)\u00a0Structure-based stabilization of non-native protein-protein interactions of coronavirus nucleocapsid proteins in antiviral drug design. Journal of Medicinal Chemistry<\/li>\n<li>Jyung-Hurng Liu*,\u00a0Jun-Yi Yang,\u00a0Duen-Wei Hsu,\u00a0Yi-Hua Lai,\u00a0Yun-Pei Li,\u00a0Yi-Rung Tsai, and\u00a0Ming-Hon Hou.\u00a0(Oct\u00a02019)\u00a0Crystal Structure-Based Exploration of Arginine-Containing Peptide Binding in the ADP-Ribosyltransferase Domain of the Type III Effector XopAI Protein. International Journal\u00a0of Molecular\u00a0Sciences<\/li>\n<li>Roshan Satange, Chien-Ying Chuang,\u00a0Stephen Neidle and\u00a0Ming-Hon Hou*.\u00a0(Jul 2019)\u00a0Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation. Nucleic Acids Research<\/li>\n<li>Chen YW; Satange R; Wu PC; Jhan CR; Chang CK; Chung KR; Waring MJ; Lin SW; Hsieh LC; Hou MH*.(2018) CoII(Chromomycin)2 complex induces a conformational change of CCG repeats from i-Motif to base-extruded DNA duplex. International Journal of Molecular Sciences<\/li>\n<li>Wu PC, Tzeng SL, Chang CK, Kao YF, Waring MJ, Hou MH*. (2018) Cooperative recognition of T:T mismatch by echinomycin causes structural distortions in DNA duplex Nucleic Acids Research<\/li>\n<li>Satange R; Chang CK; Hou, MH*. (2018) A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding. Nucleic acids research<\/li>\n<li>Liu CH, Chen YT, Hou MH, Hu NJ, Chen CS, Shaw JF. (2018) Crystallographic analysis of the Staphylococcus epidermidis lipase involved in esterification in aqueous solution. Acta Crystallographica Section F-Structural Biology Communications<\/li>\n<li>Huang TY; Chang CK; Kao YF; Chin CH; Ni CW; Hsu HY; Hu NJ; Hsieh LC; Chou SH; Lee IR; Hou MH*. (2017) Parity-dependent hairpin configurations of repetitive DNA sequence promote slippage associated with DNA expansion. Proceedings of the National Academy of Sciences of the United States of America<\/li>\n<li>Tseng WH; Chang CK; Wu PC; Hu NJ; Lee GH; Tzeng CC; Neidle S; Hou MH*. (2017) Induced-fit recognition of CCG trinucleotide repeats by a nickel chromomycin complex results in large-scale DNA deformation. Angewandte Chemie-International Edition<\/li>\n<li>Lin YH; Chuang SM; Wu PC; Chen CL; Jeyachandran S; Lo SC; Huang HS; Hou MH*. (2016) Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA. Scientific Reports<\/li>\n<li>Liu CL; Hung HC; Lo SC; Chiang CH; Chen IJ; Hsu JT; Hou MH*. (2016) Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development. Scientific Reports<\/li>\n<li>Hou MH; Chuang CY; Ko TP; Hu NJ; Chou CC; Shih YP; Ho CL; Wang AH. (2016) Crystal structure of vespid phospholipase A(1) reveals insights into the mechanism for cause of membrane dysfunction. Insect Biochemistry And Molecular Biology<\/li>\n<li>Chang CK; Jeyachandran S; Hu NJ; Liu CL; Lin SY; Wang YS; Chang YM; Hou MH*. (2016) Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein. Molecular Biosystems<\/li>\n<li>Wang YS; Chang CK; Hou MH*. (2015) Crystallographic analysis of the N-terminal domain of Middle East respiratory syndrome coronavirus nucleocapsid protein. Acta Crystallographica Section F-Structural Biology Communications<\/li>\n<li>Lin, S.Y., Liu, C.L., Chang, Y.M., Zhao, J., Perlman, S. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2014) Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target. Journal of medicinal chemistry, 57, 2247-2257.<\/li>\n<li>Chang, C.K., Hou, M.H., Chang, C.F., Hsiao, C.D. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2014) The SARS coronavirus nucleocapsid protein&#8211;forms and functions. Antiviral research, 103, 39-50.<\/li>\n<li>Chen, I.J., Yuann, J.M., Chang, Y.M., Lin, S.Y., Zhao, J., Perlman, S., Shen, Y.Y., Huang, T.H. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2013) Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein. Biochimica et biophysica acta, 1834, 1054-1062.<\/li>\n<li>Lo, Y.S., Tseng, W.H., Chuang, C.Y. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2013). The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats. Nucleic Acids Res 41, 4284-94.<\/li>\n<li>Chen, Y.W. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2013) The binding of the Co(II) complex of dimeric chromomycin A3 to GC sites with flanking G:G mismatches. Journal of inorganic biochemistry, 121, 28-36.<\/li>\n<li>Lo, Y.S., Lin, S.Y., Wang, S.M., Wang, C.T., Chiu, Y.L., Huang, T.H. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2013). Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein. FEBS Lett 587, 120-7.<\/li>\n<li>Liang, F.Y., Lin, L.C., Ying, T.H., Yao, C.W., Tang, T.K., Chen, Y.W. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2013). Immunoreactivity characterisation of the three structural regions of the human coronavirus OC43 nucleocapsid protein by Western blot: implications for the diagnosis of coronavirus infection. J Virol Methods 187, 413-20.<\/li>\n<li>Kuo, S.M., Kao, H.W.,\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>, Wang, C.H., Lin, S.H. and Su, H.L. (2013). Evolution of infectious bronchitis virus in Taiwan: positively selected sites in the nucleocapsid protein and their effects on RNA-binding activity. Vet Microbiol 162, 408-18.<\/li>\n<li>Hsu, C.W., Kuo, C.F., Chuang, S.M. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2013). Elucidation of the DNA-interacting properties and anticancer activity of a Ni(II)-coordinated mithramycin dimer complex. Biometals 26, 1-12.<\/li>\n<li>Chen, Y.W. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2013). The binding of the Co(II) complex of dimeric chromomycin A3 to GC sites with flanking G:G mismatches. J Inorg Biochem 121, 28-36.<\/li>\n<li>Yuann, J.M., Tseng, W.H., Lin, H.Y. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2012). The effects of loop size on Sac7d-hairpin DNA interactions. Biochim Biophys Acta 1824, 1009-15.<\/li>\n<li>Wu, M.R.,<span class=\"Span-Author\">Hou,M.H.<\/span>, Lin, Y.L. and Kuo, C.F. (2012). 2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes. J Agric Food Chem 60, 7262-9.<\/li>\n<li>Wang, S.Y. et al. (2012). Spermine attenuates the action of the DNA intercalator, actinomycin D, on DNA binding and the inhibition of transcription and DNA replication. PLoS One 7, e47101.<\/li>\n<li>Hung, H.C. et al. (2012). Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching. Anal Chem 84, 6391-9.<\/li>\n<li>Hsu, C.W., Chuang, S.M., Wu, W.L. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>\u00a0(2012). The crucial role of divalent metal ions in the DNA-acting efficacy and inhibition of the transcription of dimeric chromomycin A3. PLoS One 7, e43792.<\/li>\n<li>Chang, Y.M., Chen, C.K. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2012). Conformational Changes in DNA upon Ligand Binding Monitored by Circular Dichroism. Int J Mol <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<p>13, 3394-413.<\/p>\n<ul>\n<li>Chang, Y.M., Chen, C.K., Chang, Y.C., Jeng, W.Y.,<span class=\"Span-Author\">Hou,M.H.<\/span>\u00a0and Wang, A.H. (2012). Functional studies of ssDNA binding ability of MarR family protein TcaR from Staphylococcus epidermidis. PLoS One 7, e45665.<\/li>\n<li>Kuo, S.M., Wang, C.H.,<span class=\"Span-Author\">Hou,M.H.<\/span>, Huang, Y.P., Kao, H.W. and Su, H.L. (2010). Evolution of infectious bronchitis virus in Taiwan: characterisation of RNA recombination in the nucleocapsid gene. Vet Microbiol 144, 293-302.<\/li>\n<li>Chen, I.J., Chou, C.C., Liu, C.L., Lee, C.C., Kan, L.S. and\u00a0<span class=\"Span-Author\">Hou,M.H.<\/span>(2010). Crystallization and preliminary X-ray diffraction analysis of the N-terminal domain of human coronavirus OC43 nucleocapsid protein. Acta Crystallogr Sect F Struct Biol Cryst Commun 66, 815-8.<\/li>\n<li>Lu, W.J., Wang, H.M., Yuann, J.M., Huang, C.Y. and<span class=\"Span-Author\">Hou, M.H.<\/span>(2009). The impact of spermine competition on the efficacy of DNA-binding Fe(II), Co(II), and Cu(II) complexes of dimeric chromomycin A(3). J Inorg Biochem 103, 1626-33.&gt;<\/li>\n<li>Huang, C.Y., Hsu, Y.L., Chiang, W.L. and\u00a0<span class=\"Span-Author\">Hou, M.H.<\/span>(2009). Elucidation of the stability and functional regions of the human coronavirus OC43 nucleocapsid protein. Protein <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<\/ul>\n<p>18, 2209-18.<\/p>\n<ul>\n<li><span class=\"Span-Author\">Hou, M.H.<\/span>, Lu, W.J., Lin, H.Y. and Yuann J.M. (2008) Studies of sequence-specific DNA binding, DNA cleavage, and topoisomerase I Inhibition by the dimeric chromomycin A3 complexed with Fe(II). Biochemistry., 47, 5493-5502.<\/li>\n<li>Tang, T.K., Wu, P.J., Chen, S.T.,\u00a0<span class=\"Span-Author\">Hou, M.H.<\/span>, Hong, M.H., Pan, F.M., Yu, H.M., Chen, J.H., Yao, C.W. and Wang, A.H.-J. (2005) Biochemical and immunological studies of nucleocapsid proteins of severe acute respiratory and 229E human coronaviruses.. Proteomics 5,925-37.<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.<\/span>\u00a0and Wang A.H.-J. (2005) Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicity. Nucleic Acids Res. 33,1352-61<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.<\/span>, Robinson H., Gao Y.G. and Wang A.H.-J. (2004) Crystal structure of the Mg2+-(chromomycin A3)2-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by metal ion. Nucleic Acids Res, 32, 2214-2222. (Featured on Cover)<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.<\/span>, Robinson H., Gao Y.G. and Wang A.H.-J. (2002). Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases. Nucleic Acids Res., 30, 4910-4917. (Featured on Cover)<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.<\/span>, Lin, S.B., Yuann J.M., Lin W.C., Wang A.H.-J. and Kan L.S. (2001) Effects of polyamines on the thermal stability and formation kinetics of DNA duplexes with abnormal structure. Nucleic Acids Res., 29, 5121-5128.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u8a0e\u6703\u8ad6\u6587 (*Invited speaker)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li style=\"list-style-type: none;\">\n<ol class=\"Exp\">\n<li style=\"list-style-type: none;\">\n<ol class=\"Exp\">\n<li>Roshan Satange and Ming-Hon Hou*(2018, May) Synergistic intercalation of echinomycin and actinomycin D to DNA duplex with T:T mismatch causes single strand deformation. pp.104(Poster). In: The 23rd Biophysics Conference; 2018 May 23-25; Taichung, Taiwan<\/li>\n<li>Yun-Jean Lin and Ming-Hon Hou*(2018, May) Structural study of the specific interactions between echinomycin and methylated DNA containing the CCG motif .pp.103(Poster). In: The 23rd Biophysics Conference; 2018 May 23-25; Taichung, Taiwan<\/li>\n<li>Hsiang-Ti Huang and Ming-Hon Hou*(2018, May) Structural basis for the binding of Echinomycin to DNA duplex containing I:C mismatch. pp.91(Poster). In: The 23rd Biophysics Conference; 2018 May 23-25; Taichung, Taiwan<\/li>\n<li>Pei-Ching Wu, Shu-Ling Tzeng, Chung-ke Chang, Ya-Fen Kao, Michael J. Waring and Ming-Hon Hou* (2018, May) Cooperative recognition of T:T mismatch by echinomycin causes structural distortions in DNA duplex. pp.106(Poster). In: The 23rd Biophysics Conference; 2018 May 23-25; Taichung, Taiwan<\/li>\n<li>Ching-Ming Chien, Jia-Ning Hsu and Ming-Hon Hou* (2018, May) Homology Modeling and Crystallization of N-terminal domain of Porcine Epidemic Diarrhea Virus Nucleocapsid Protein. pp.90(Poster). In: The 23rd Biophysics Conference; 2018 May 23-25; Taichung,Taiwan<\/li>\n<li>Jing-Yi Zeng, Tzu-Jung Huang and Ming-Hon Hou* (2018, May) The terminal base pairs determine the conformation of DNA duplex with G:T mismatch. pp.117(Poster). In: The 23rd Biophysics Conference; 2018 May 23-25; Taichung, Taiwan<\/li>\n<li>Ming-Hon Hou (2018, May) Binding of small molecules to trinucleotide DNA repeats associated with fragile X syndrome. pp.34(Oral). In: The 23rd Biophysics Conference; 2018 May 23-25; Taichung, Taiwan<\/li>\n<li>Hou, MH; Hsu, CN (Dec, 2017) Structural basis for identification of the interface of the N-terminal domain of CoV N protein dimer as a target for drug development. pp. 196 (Abstract POS501). In: the 31st Annual Symposium ofThe Protein Society, 2017 July 24\u201327, Montreal, Canada.<\/li>\n<li>Lin, S.Y., Liu, C.L., Chang, Y.M., and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>(2012, Dec). Probing the N-terminal domain of coronavirus nucleocapsid protein as a potent target for antiviral drug development.. 2012 Taiwan Society for Biochemistry and Molecular Biology.<\/li>\n<li>Lin, Y.H., Chen, C.L., Huang, H.S., and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>\u00a0(2012, Dec). The study of anthrax[1, 2-d] imidazole-6,11-dione derivatives bound to the potassium form of human telomere G-quadruplex.. 2012 Taiwan Society for Biochemistry and Molecular Biology.<\/li>\n<li>Chen, Y.W., and<span class=\"Span-Author\">Hou, M.H.*<\/span>\u00a0(2012, Dec). The binding of the Co(II) complex of dimeric chromomycin A3 to GC sites with flanking G:G mismatches.. 2012 Taiwan Society for Biochemistry and Molecular Biology.<\/li>\n<li>Tseng, W. H., Yuann, J. M., Lin, H. Y., and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>(2012). The effects of loop size on Sac7d-hairpin DNA interactions.. 17th Joint International Conference of Biophysics and Annual Conference of the Biophsical Society of ROC.<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.*<\/span>., Liu, C.L., Chen, I.J. and Chou, C.C. (2011). Identification of the N-terminal domain of human coronaviral nucleocapsid protein as a potential antiviral target. The 36th FEBS congress.<\/li>\n<li>Hsu, CW., Chuang, S.M. and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>\u00a0(2011). Comparison of DNA-binding properties and ant proliferative effects for chromomycin A3 dimer chelated with various divalent metal ions. 22nd FAOBMB conference.<\/li>\n<li>Liu, C.L., Chen, I.J. and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>(2011). Identification of the N-terminal domain of human coronaviral nucleocapsid protein as a potential antiviral target . 22nd FAOBMB conference.<\/li>\n<li>Chen, Y.W. and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>(2010). Probing the interaction of the residue Y148 in influenza A virus nucleoprotein involved in RNA-binding. The Taiwan society for biochemistry and molecular biology.<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.*<\/span>\u00a0Lu,W.J., Wang, H.M., Yuann, J.M., and Huang, C.Y. (2010). The impact of spermine competition on the efficacy of DNA-binding Fe(II), Co(II), and Cu(II) complexes of dimeric chromomycin A(3). 4th Asian Bioinorganic Chemistry Conference.<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.*<\/span>, Lu,W.J., Huang, C.Y., Fan, R.J., and Yuann, J.M. (2010). Effects of polyamines on the DNA-reactive properties of dimeric mithramycin complexed with cobalt(II): implications for anticancer therapy . 24th International Conference on Organometallic Chemistry.<\/li>\n<li>Lo, Y.S., Chiu, Y.L. and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>(2010). The crucial role of C-terminal tail of human coronavirus 229E nucleocapsid protein in oligomerization. The Taiwan society for biochemistry and molecular biology.<\/li>\n<li>Chiang, C.H., Wu, F.C. and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>(2009). Probing the crucial residues of influenza virus (H1N1) nucleocapsid for RNA-bunding. 14th Joint International Conference of Biophysics and Annual Conference of the Biophsical Society of ROC.<\/li>\n<li>Chiu, Y.L, Lo, Y.S. and\u00a0<span class=\"Span-Author\">Hou, M.H.*<\/span>(2009). Characterization of the C-terminal domain of human coronavirus 229E nucleocapsid protein in RNA-binding and oligomerization. 14th Joint International Conference of Biophysics and Annual Conference of the Biophisical Society of ROC.<\/li>\n<li><span class=\"Span-Author\">Hou, M.H.*<\/span>\u00a0Chiang, C. H., Wu, F. C. and Lo, Y. S. (2009). Probing the crucial residues of influenza virus (H1N1) nucleoprotein for RNA-binding. VIII European Symposium of The Protein Society.<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<p>&nbsp;<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<ul class=\"team-manager-free-items-style2-social_media_team-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-teamprofiles-1739\">\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-title-1739\">\r\n\t\t\t\t\t\t\t\t<a href=\"\" data-featherlight=\"#fl1292240553\">\r\n\t\t\t\t\t\t\t\t\t\u4faf\u660e\u5b8f\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-post-1739\">\r\n\t\t\t\t\t\t\t\t\u6559\u6388\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<p style=\"display:block\" class=\"team-manager-free-items-style2-team-description-1739\">\r\n\t\t\t\t\t\t\t\t\u7814\u7a76\u65b9\u5411:\u85e5\u7269\u8a2d\u8a08\uff0c\u751f\u7269\u7269\u7406\uff0c\u86cb\u767d\u8cea\u5de5\u7a0b\t\t\t\t\t\t\t<\/p>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t\t<div class=\"teamshowcasefree-col-lg-3 teamshowcasefree-col-md-2 teamshowcasefree-col-sm-2 teamshowcasefree-col-xs-1\">\r\n\t\t\t\t\t<div class=\"team-manager-free-items-style2-1739\">\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-pic-1739\">\r\n\t\t\t\t\t\t\t<a href=\"#\" data-featherlight=\"#fl1162905701\">\r\n\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_ChuYenWei.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t<div class=\"lightbox\" id=\"fl1162905701\">\r\n\t\t\t\t\t\t\t\t\t<div class=\"team_popup_container-1739\">\r\n\t\t\t\t\t\t\t\t\t\t<h2>\u6731\u5f65\u7152<\/h2>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area_img-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_ChuYenWei.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_contact_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\"><a href=\"mailto:ywchu@nchu.edu.tw\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\tywchu@nchu.edu.tw<\/a><\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">(04)22840338 #7041(\u8fa6\u516c\u5ba4) #7061(\u5be6\u9a57\u5ba4)<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">\u52d5\u690d\u7269\u9632\u6aa2\u75ab\u5927\u6a137\u6a13704\u5ba4<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<ul class=\"team-manager-popup-items-social-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_right_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/orcid.org\/0000-0002-5525-4011\"><img loading=\"lazy\" class=\"wp-image-2595 alignright\" src=\"http:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png\" alt=\"\" width=\"79\" height=\"79\" srcset=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png 150w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-24x24.png 24w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-36x36.png 36w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-48x48.png 48w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948.png 190w\" sizes=\"(max-width: 79px) 100vw, 79px\" \/><\/a><\/p>\n<p>\u7814\u7a76\u5ba4:<a href=\"http:\/\/predictor.nchu.edu.tw\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u81ea\u7136\u8a08\u7b97\u8207\u751f\u7269\u8cc7\u8a0a\u6838\u5fc3\u5be6\u9a57\u5ba4<\/a><\/p>\n<h4>\u7c21\u8981\u7d93\u6b77<\/h4>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"20%\">\u8077\u7a31<\/th>\n<th width=\"54%\">\u670d\u52d9\u55ae\u4f4d<\/th>\n<th width=\"26%\">\u8d77\u8a16\u5e74\u6708<\/th>\n<\/tr>\n<tr>\n<td>Review Editor<\/td>\n<td>Frontiers in Digital Public Health<\/td>\n<td>2021\/07 &#8211; present<\/td>\n<\/tr>\n<tr>\n<td>Guest Editor<\/td>\n<td>Frontiers in Genetics<\/td>\n<td>2021 &#8211; present<\/td>\n<\/tr>\n<tr>\n<td>Editor<\/td>\n<td>Journal of Biochemistry and Molecular Biology Research<\/td>\n<td>2014\/10 &#8211; present<\/td>\n<\/tr>\n<tr>\n<td>Lead Guest Editor<\/td>\n<td>Journal of Neuroscience and Neuroengineering<\/td>\n<td>2012 &#8211; 2013<\/td>\n<\/tr>\n<tr>\n<td>\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240<\/td>\n<td>2019\/08 -present<\/td>\n<\/tr>\n<tr>\n<td>\u526f\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240<\/td>\n<td>2012\/08 -2019\/07<\/td>\n<\/tr>\n<tr>\n<td>\u7814\u7a76\u767c\u5c55\u7d44\u7d44\u9577<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u8a08\u7b97\u6a5f\u53ca\u8cc7\u8a0a\u7db2\u8def\u4e2d\u5fc3<\/td>\n<td>2013\/08 \u2013 2015\/08<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240<\/td>\n<td>2008\/08 \u2013 2012\/07<\/td>\n<\/tr>\n<tr>\n<td>\u54a8\u8a62\u5be9\u67e5\u59d4\u54e1<\/td>\n<td>\u4e2d\u83ef\u6c11\u570b \u884c\u653f\u9662 \u885b\u751f\u7f72<\/td>\n<td>2006 &#8211; present<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e9e\u6d32\u5927\u5b78 \u751f\u7269\u8cc7\u8a0a\u5b78\u7cfb<\/td>\n<td>2006\/08 &#8211; 2008\/07<\/td>\n<\/tr>\n<tr>\n<td>\u5c08\u4efb\u8b1b\u5e2b<\/td>\n<td>\u5143\u57f9\u79d1\u6280\u5927\u5b78 \u8cc7\u8a0a\u7ba1\u7406\u5b78\u7cfb<\/td>\n<td>2005\/08 &#8211; 2006\/07<\/td>\n<\/tr>\n<tr>\n<td>\u5c08\u4efb\u8b1b\u5e2b<\/td>\n<td>\u4e2d\u570b\u79d1\u6280\u5927\u5b78 \u8cc7\u8a0a\u7ba1\u7406\u7cfb<\/td>\n<td>2003\/09 &#8211; 2005\/07<\/td>\n<\/tr>\n<tr>\n<td>\u9867\u554f<\/td>\n<td>\u53f0\u74a7\u5be6\u696d\u80a1\u4efd\u6709\u9650\u516c\u53f8 \u8cc7\u8a0a\u8655<\/td>\n<td>1998\/03 &#8211; 2000\/03<\/td>\n<\/tr>\n<tr>\n<td>\u5c08\u4efb\u8b1b\u5e2b<\/td>\n<td>\u53f0\u7063\u96fb\u5b50\u5316\u591a\u5143\u6559\u80b2\u5354\u6703 \u96fb\u5b50\u5316\u5b78\u6821<\/td>\n<td>1997\/03 &#8211; 1999\/06<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb<\/td>\n<td>\u570b\u7acb\u4ea4\u901a\u5927\u5b78 \u8cc7\u8a0a\u5de5\u7a0b\u7814\u7a76\u6240<\/td>\n<td>1998\/09 &#8211; 2006\/07<\/td>\n<\/tr>\n<tr>\n<td>\u78a9\u58eb<\/td>\n<td>\u570b\u7acb\u4ea4\u901a\u5927\u5b78 \u8cc7\u8a0a\u79d1\u5b78\u7814\u7a76\u6240<\/td>\n<td>1996\/09 &#8211; 1998\/07<\/td>\n<\/tr>\n<tr>\n<td>\u5b78\u58eb<\/td>\n<td>\u570b\u7acb\u4ea4\u901a\u5927\u5b78 \u8cc7\u8a0a\u79d1\u5b78\u7cfb<\/td>\n<td>1992\/09 &#8211; 1996\/07<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u69ae\u8b7d<\/h4>\n<table class=\"Table-PersonalExp\" style=\"height: 129px;\" width=\"994\">\n<tbody>\n<tr>\n<th width=\"14%\">\u6642\u9593<\/th>\n<th width=\"86%\">\u5167\u5bb9<\/th>\n<\/tr>\n<tr>\n<td>2022<\/td>\n<td>\u69ae\u7372\u672c\u6821111\u5b78\u5e74\u5ea6\u7279\u8058\u6559\u6388<\/td>\n<\/tr>\n<tr>\n<td>2022<\/td>\n<td>\u53c3\u52a0\u300c\u6c34\u8cc7\u6599\u61c9\u7528\u7af6\u8cfd\u300d\u4ee5\u300c\u4f7f\u7528\u4eba\u5de5\u667a\u6167\u6f14\u7b97\u6cd5\u958b\u767c\u5168\u65b9\u4f4d\u6c34\u5eab\u667a\u6167\u7ba1\u7406\u7d1a\u9810\u8b66\u5e73\u53f0\u300d\u69ae\u7372\u300c\u4f73\u4f5c\u300d<\/td>\n<\/tr>\n<tr>\n<td>2021<\/td>\n<td>\u300c\u61c9\u7528\u4f5c\u7269\u751f\u7406\u6307\u6a19\u5efa\u7acb\u9700\u6c34\u8d85\u524d\u9810\u8b66\u7cfb\u7d71\u300d\u5165\u570d\u300c2021\u672a\u4f86\u79d1\u6280\u734e\u300d\u53c3\u5c55\u6280\u8853<\/td>\n<\/tr>\n<tr>\n<td>2021<\/td>\n<td>\u69ae\u7372\u4e2d\u8208\u5927\u5b78110\u5b78\u5e74\u5ea6\u7522\u5b78\u7e3e\u512a\u6559\u5e2b<\/td>\n<\/tr>\n<tr>\n<td>2018<\/td>\n<td>\u69ae\u7372\u4e2d\u8208\u5927\u5b78107\u5b78\u5e74\u5ea6\u512a\u8058\u6559\u5e2b<\/td>\n<\/tr>\n<tr>\n<td>2018<\/td>\n<td>\u570b\u969b\u6703\u8b70The second International Conference on Medical and Health Informatics\u69ae\u7372\u6700\u4f73\u8ad6\u6587\u734e<\/td>\n<\/tr>\n<tr>\n<td>2015<\/td>\n<td>\u69ae\u7372\u6559\u80b2\u90e8\u6559\u80b2\u90e8\u751f\u6280\u7522\u696d\u5275\u65b0\u5275\u696d\u4eba\u624d\u57f9\u80b2\u8a08\u756b\u751f\u6280\u5275\u65b0\u5275\u696d\u734e\u6700\u4f73\u4eba\u6c23\u734e<\/td>\n<\/tr>\n<tr>\n<td>2014<\/td>\n<td>\u570b\u969b\u6703\u8b70 25th International Conference on Information Management \u69ae\u7372\u6700\u4f73\u8ad6\u6587\u734e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u5b78\u8207\u7814\u7a76<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u7a76\u65b9\u5411<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>\u751f\u7269\u8cc7\u8a0a\u6f14\u7b97\u6cd5<\/li>\n<li>\u8a08\u7b97\u8868\u89c0\u907a\u50b3\u5b78<\/li>\n<li>\u751f\u91ab\u8cc7\u8a0a\u5b78<\/li>\n<li>\u6f14\u5316\u5f0f\u8a08\u7b97<\/li>\n<li>\u985e\u795e\u7d93\u7db2\u8def<\/li>\n<li>\u6a21\u7cca\u7cfb\u7d71<\/li>\n<li>\u8cc7\u6599\u63a2\u52d8<\/li>\n<li>\u667a\u6167\u8a08\u7b97<\/li>\n<li>\u81ea\u7136\u8a08\u7b97<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u6388\u8ab2\u7a0b:<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u8ab2\u7a0b\u540d\u7a31<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\n<p class=\"pHead\">\u81ea\u7136\u8a08\u7b97\u61c9\u7528\u7279\u8ad6(\u57fa\u8cc7\u6240)\u3001\u6a5f\u5668\u5b78\u7fd2(\u8cc7\u5de5\u7cfb)\u3001\u751f\u7269\u8cc7\u8a0a\u767c\u5c55\u73fe\u6cc1(\u5206\u751f\u6240)\u3001 \u751f\u7269\u8cc7\u8a0a\u7a0b\u5f0f\u8a2d\u8a08(\u57fa\u8cc7\u6240)\u3001\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u751f\u79d1\u7cfb)\u3001\u61c9\u7528\u57fa\u56e0\u9ad4\u5b78\u53ca\u751f\u7269 \u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u57fa\u8cc7\u6240)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u8457\u4f5c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u671f\u520a\u8ad6\u6587 (*Corresponding author)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>Chi-Hua Tung, Yi-Sheng Chang, Kai-Po Chang and Yen-Wei Chu* (2021) NIgPred: Class-Specific Antibody Prediction for Linear B-Cell Epitopes Based on Heterogeneous Features and Machine-Learning Approaches\uff0cViruses, 13(8), 1531.<\/li>\n<li>Chi-Wei Chen, Lan-Ying Huang, Chia-Feng Liao, Kai-Po Chang and Yen-Wei Chu* (2020) GasPhos: Protein Phosphorylation Site Prediction Using a New Feature Selection Approach with a GA-Aided Ant Colony System, International Journal of Molecular Sciences, 21(21):7891.<span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Ching-Hsuan Chien, Chi-Chang Chang, Shih-Huan Lin, Chi-Wei Chen, Zong-Han Chang and\u00a0<span class=\"star\">Yen-Wei Chu<\/span>* (2020 )N-GlycoGo: Predicting Protein N-glycosylation Sites on Imbalanced Data Sets by Using Heterogeneous and Comprehensive Strategy, IEEE Access, doi:10.1109\/ACCESS.2020.3022629.\u00a0<b>(SCI)<\/b><\/li>\n<li>Kai-Po Chang, John Wang, Chi-Chang Chang,and\u00a0<span class=\"star\">Yen-Wei Chu<\/span>* (2020) Development of a Novel Tool for the Retrieval and Analysis of Hormone Receptor Expression Characteristics in Metastatic Breast Cancer via Data Mining on Pathology Reports, BioMed Research International, 2020(7):2654815.<b>(SCI)<\/b><\/li>\n<li><span class=\"star\">Yen-Wei Chu<\/span>, Ching-Hsuan Chien, Mei-I Sung, Chi-Wei Chen, and Yu-Ting Chen (2020) dBMHCC: a comprehensive Hepatocellular carcinoma (HCC) biomarker database provides a reliable prediction system for novel HCC phosphorylated biomarkers, PLoS ONE, 15(6): e0234084.\u00a0<b>(SCI)<\/b><\/li>\n<li>Chi-Hua Tung, Ching-Hsuan Chien, Chi-Wei Chen, Lan-Ying Huang, Yu-Nan Liu and\u00a0<span class=\"star\">Yen-Wei Chu<\/span>* (2020) QUATgo: Protein quaternary structural attributes predicted by two-stage machine learning approaches with heterogeneous feature encoding, PLoS ONE, 15(4): e0232087.\u00a0<b>(SCI)<\/b><\/li>\n<li>Chi-Wei Chen, Meng-Han Lin, Chi-Chou Liao, Hsung-Pin Chang and\u00a0<span class=\"star\">Yen-Wei Chu<\/span>* (2020) iStable 2.0: Predicting protein thermal stability changes by integrating various characteristic modules, Computational and Structural Biotechnology Journal, 18:622-630.\u00a0<b>(SCI: 6.018)<\/b><\/li>\n<li><span class=\"star\">Yen-Wei Chu<\/span>, Kai-Po Chang, Chi-Wei Chen, Yu-Tai Liang, Zhi Thong Soh and Li\u2010Ching Hsieh* (2020) miRgo: integrating various off-the-shelf tools for identification of microRNA\u2013target interactions by heterogeneous features and a novel evaluation indicator, Scientific Reports, 10:1466.\u00a0<b>(SCI)<\/b><\/li>\n<li>Jehn-Hwa Kuo, Chi-Chang Chang, Chi-Wei Chen, Heng-Hao Liang, Chih-Yen Chang and\u00a0<span class=\"star\">Yen-Wei Chu*<\/span>\u00a0(2020) Sequence-Based Structural B-cell Epitope Prediction by Using Two Layer SVM Model and Association Rule Features, Current Bioinformatics, 15(3), doi:10.2174\/1574893614666181123155831\u00a0<b>(SCI)<\/b><\/li>\n<li>Jone-Han Liu, Chi-Chang Chang, Chi-Wei Chen, Li-Ting Wong and Yen-Wei Chu* (2019) Conservation region finding for influenza A viruses by machine learning methods of N-linked glycosylation sites and B-cell epitopes, Mathematical Biosciences, 315:108217. <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Chi-Chou Liao, Liang-Jwu Chen, Shuen-Fang Lo, Chi-Wei Chen and Yen-Wei Chu* (2019) EAT-Rice: A predictive model for flanking gene expression of T-DNA insertion activation-tagged rice mutants by machine learning approaches, PLoS Comput Biol, 15(5):e1006942. <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Kai-Po Chang, Yen-Wei Chu* and John Wang (2019) Analysis of Hormone Receptor Status in Primary and Recurrent Breast Cancer Via Data Mining Pathology Reports, Open Medicine, 20(14): 91-98. <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Jehn-Hwa Kuo, Chi-Chang Chang, Chi-Wei Chen, Heng-Hao Liang, Chih-Yen Chang and Yen-Wei Chu* (2019) Sequence-Based Structural B-cell Epitope Prediction by Using Two Layer SVM Model and Association Rule Features, Current Bioinformatics, DOI: 10.2174\/1574893614666181123155831 <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Yu-Ting Chen, Chi-Chang Chang, Chi-Wei Chen, Kuan-Chun Chen and Yen-Wei Chu* (2019) MADS-Box Gene Classification in Angiosperms by Clustering and Machine Learning Approaches, Frontiers in Genetics, 8(9): 707. <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Chi-Wei Chen, Kai-Po Chang, Cheng-Wei Ho, Hsung-Pin Chang and Yen-Wei Chu* (2018) KStable: A Computational Method for Predicting Protein Thermal Stability Changes by K-Star with Regular-mRMR Feature Selection, Entropy, 20(12): 988. <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Chi-Chang Chang,Chi-Hua Tung,Chi-Wei Chen,Chin-Hau Tu and Yen-Wei Chu* (2018) SUMOgo: Prediction of sumoylation sites on lysines by motif screening models and the effects of various post-translational modifications. scientific report, 19;8(1):15512. doi: https:\/\/doi.org\/10.1038\/s41598-018-33951-5 <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Quan Zou, Chi-Wei Chen, Hao-Chen Chang and Yen-Wei Chu* (2018) Identifying Cleavage Sites of Gelatinases A and B by Integrating Feature Computing Models. Journal of Universal Computer Science, Vol. 24, No. 6, pp. 711-724 <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Chi-Chou Huang, Chi-Chang Chang, Chi-Wei Chen, Shao-yu Ho, Hsung-Pin Chang and Yen-Wei Chu* (2018) PClass: Protein Quaternary Structure Classification by Using Bootstrapping Strategy as Model Selection. Genes, Vol. 9, No. 2, pii: E91. doi: 10.3390\/genes9020091 <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Chi-Wei Chen, Chi-Chang Chang, Hui-Chih Hung, Hsung-Pin Chang and Yen-Wei Chu* (2018) Constructing Feature Models for Citrullination Sites Prediction. Journal of Quality, Vol. 25, No. 3, doi:10.6220\/joq.201806_25(3).0004 <span style=\"text-transform: uppercase;\"><b>(EI)<\/b><\/span><\/li>\n<li>Chi-Hua Tung, Pei-Wei Shueng, Yen-Wei Chu*, Chi-Wei Chen, Chian-Ying Chen (2017) Identifying Post-Translational Modification Crosstalks for Breast Cancer. Journal of Computing Science and Engineering, Vol. 11, No. 4, pp. 111-120 <span style=\"text-transform: uppercase;\"><b>(EI)<\/b><\/span><\/li>\n<li>Chi-Hua Tung, Chi-Wei Chen, Han-Hao Sun, Yen-Wei Chu* (2017) Predicting human protein subcellular localization by heterogeneous and comprehensive approaches, PLoS ONE, 12(6):e0178832. doi: 10.1371\/journal.pone.0178832 <span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<li>Chi-Hua Tung, Chi-Wei Chen, Ren-Chao Guo, Hui-Fuang Ng, Yen-Wei Chu* (2016) QuaBingo: A Prediction System for Protein Quaternary Structure Attributes Using Block Composition, BioMed Research International, 2016:9480276, doi:10.1155\/2016\/9480276 <span style=\"text-transform: uppercase;\"><b>(SCI : 2.134)<\/b><\/span><\/li>\n<li>Han-Ju Chien+, Yen-Wei Chu+, Chi-Wei Chen, Yu-Min Juang, Min-Wei Chien, Chih-Wei Liu, Chia-Chang Wu, Jason T.C. Tzen and Chien-Chen Lai* (2016) 2-DE combined with two-layer feature selection accurately establishes the origin of oolong tea, Food Chemistry, 211:392-9, doi:10.1016\/j.foodchem.2016.05.043 <span style=\"text-transform: uppercase;\"><b>(SCI: 4.052<\/b><\/span> , Co-first Author)<\/li>\n<li>Chi-Wei Chen, Jerome Lin, Yen-Wei Chu* (2013) iStable: Off-the-shelf Predictor Integration for Predicting Protein Stability Changes, BMC Bioinformatics, 14(suppl 2):S5, doi:10.1186\/1471-2105-14-S2-S5 <span style=\"text-transform: uppercase;\"><b>(SCI:<\/b><\/span>2.435, ranking: 17.9%)<\/li>\n<li>Wei-Jie Pan, Chi-Wei Chen, Heng-Hao Liang, Yen-Wei Chu* (2012) Selecting High Efficacy siRNAs by Computational Models, Advanced Science Letters, 18: 141-144. <span style=\"text-transform: uppercase;\"><b>(SCI:<\/b><\/span>1.253, ranking: 25%)<\/li>\n<li>Chang-Hsien Yang, Yu-Yun Chang, Chi-Wei Chen, Min-Cheng Chan, Yen-Wei Chu* (2012) iMADS: The Class Identification of MADS-box Gene on Angiosperm, Advanced Science Letters, 18: 170-175.<span style=\"text-transform: uppercase;\"><b>(SCI:<\/b><\/span>1.253, ranking: 25%)<\/li>\n<li>Po-Chang Chang, Wei-Jie Pan, Chi-Wei Chen,Yu-Ting Chen and Yen-Wei Chu* (2012) DEsi: an design engine of siRNA that integrates SVMs prediction and feature filters, Biocatalysis and Agricultural Biotechnology, doi: 10.1016\/j.bcab.2012.01.005<\/li>\n<li>Wei-Jie Pan, Chi-Wei Chen and Yen-Wei Chu* (2011)siPRED: Predicting siRNA efficacy using various characteristic methods, PLoS ONE, doi: 10.1371\/journal.pone.0027602 <span style=\"text-transform: uppercase;\"><b>(SCI :3.057)<\/b><\/span><\/li>\n<li>Yu-Yun Chang+,Yen-Wei Chu+, Chi-Wei Chen, Wei-Ming Leu, Hsing-Fun Hsu and Chang-Hsien Yang* (2011) Characterization of Oncidium &#8216;Gower Ramsey&#8217; Transcriptomes using 454 GS-FLX Pyrosequencing and Their Application to the Identification of Genes Associated with Flowering Time, Plant and Cell Physiology, 52(9): 1532-1545 <span style=\"text-transform: uppercase;\"><b>(SCI: 4.319<\/b><\/span> , Co-first Author)<\/li>\n<li>Hui-Fuang Ng, Zeng-Wei Hong and Yen-Wei Chu (2008) &#8220;Pose and Expression Invariant Face Recognition from a Single Training Sample Using Similarity Vector&#8221;, Journal of Cybernetics and Systems, 1(1): 21-26. <b>(International Journal)<\/b><\/li>\n<li>Yen-Wei Chu* and Chuen-Tsai Sun (2007) Problem-based Approach for Bioinformatics. International Journal of Instructional Media,Vol. 34 #4. <b>(International Journal)<\/b><\/li>\n<li>Yen-Wei Chu*, Chuen-Tsai Sun, and Chung-Yuan Huang (2006) Regularity of Protein Secondary Structures and Its Prediction. WSEAS Transactions on Systems, 2(5), pp. 380-387. <span style=\"text-transform: uppercase;\"><b>(EI)<\/b><\/span><\/li>\n<li>Chung-Yuan Huang, Chuen-Tsai Sun, and Yen-Wei Chu (2006) A Co-adaptive Approach to XCS Classifier Systems. WSEAS Transactions on Systems, 2(5), pp. 388-394. <span style=\"text-transform: uppercase;\"><b>(EI)<\/b><\/span><\/li>\n<li>Yen-Wei Chu* and. Jinn-Moon Yang (2003) Finding Regularity in Various Types of Secondary Protein Structures, Journal of Information Science and Engineering, vol. 19, pp.943-952.<span style=\"text-transform: uppercase;\"><b>(SCI)<\/b><\/span><\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5b78\u8853\u7814\u8a0e\u6703\u8ad6\u6587 (*Invited speaker)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>Chen Chi-Wei, Chin-Hau Tu and Yen-Wei Chu* (2018) SUMOylation Sites Prediction by Machine Learning Approaches, IEEE International Conference on Consumer Electronics-Taiwan. (http:\/\/edas.info\/p24335#S1569554145)<\/li>\n<li>Kai-Po Chang, Chi-Chang Chang, Yen-Wei Chu* and John Wang* (2018) BreastExtractor: A Word\/Phrase Matching-Based Text Mining Program for Automatic Extraction of Hormone Receptor Data from Free-text Pathology Reports on Breast Cancer, the second International Conference on Medical and Health Informatics. <span style=\"text-transform: capitalize;\"><b>(Best Paper Award)<\/b><\/span><\/li>\n<li>Kai-Po Chang, John Wang* and Yen-Wei Chu* (2016) Big data in pathologists\u2019 office: large-scale extraction and analysis of immunohistochemical study result in free-text pathology reports by a client-side Python script, Paper presented at 2016 Annual Meeting of Taiwan Society Of Pathology, Taipei, Taiwan.<\/li>\n<li>Ci-Jhou Liao, Liang-Jwu Chen, Yen-Wei Chu* (2014) Using machine learning approach to predict the flanking genes expression in T-DNA insertion activation-tagged rice lines, Summer Workshop on Plant Molecular Biology, Nantou County, Taiwan, July 4-6.<\/li>\n<li>Chi-Wei Chen, Hui-Chih Hung, Yen-Wei Chu* (2014) Citrullination Sites Prediction by Machine Learning Approaches, Proceedings of the 25th International Conference on Information Management (ICIM 2014), pp. 1-13. <span style=\"text-transform: capitalize;\"><b>(Best Paper Award)<\/b><\/span><\/li>\n<li>Chi-Wei Chen, Hui-Chih Hung, Yen-Wei Chu* (2013) Feature Model Integration by Evolutionary Computation for Predicting Protein Citrullination sites, Proceedings of the Taiwan Academic Network Conference 2013 (TANet 2013), pp. 1047-1052.<\/li>\n<li>Hao-Chen Chang and Yen-Wei Chu* (2013) Gelatinase Substrate Cleavage Sites Prediction Using Machine Learning and Feature Selection, Proceedings of the Taiwan Academic Network Conference 2013 (TANet 2013), pp. 1053-1058.<\/li>\n<li>Chi-Wei Chen, Jerome Lin, Yen-Wei Chu* (2013) iStable: Off-the-shelf Predictor Integration for Predicting Protein Stability Changes, The Eleventh Asia Pacific Bioinformatics Conference, Vancouver, BC, Canada, January 21-23.<\/li>\n<li>Wen-Pin Hu, Chi-Wei Chen, Jian-Shiun Chen, and Yen-Wei Chu* (2012) Evaluating various machine learning approaches for the sunspot number prediction. Symposium of university league in Changhua, Yunlin, and Chiayi, Taiwan, December 7.<\/li>\n<li>Yu-Yun Chang, Yen-Wei Chu, Wei-Ming Leu and Chang-Hsien Yang* (2011) Characterization of Oncidium &#8216;Gower Ramsey&#8217; transcriptome for using GS-FLX 454 pyrosequencing and its application for studies of flowering time associate genes. The International Conference Plant Gene Discovery Technologies. Venue. February 23- 26.<\/li>\n<li>Yu-Yun Chang, Yen-Wei Chu, Hsing-Fun Hsu, Chi-Wei Chen, Wei-Ming Leu and Chang-Hsien Yang* (2011) Characterization of Oncidium &#8216;Gower Ramsey&#8217; transcriptomes using 454 GS-FLX pyrosequencing and their application to theidentification of genes associated with flowering time. 2011 Canadian Plant Genomics Workshop, Niagara Falls, Ontario. Canada, August 22-25.<\/li>\n<li>Wei-Jie Pan, Chi-Wei Chen and Yen-Wei Chu* (2011) High efficacy siRNA selection using machine learning approach, Proceedings of 2011 Joint Conference on 7th Taiwan Software Engineering (TCSE) and 22nd Object-Oriented Technology and Applications (OOTA), pp. 94-99<\/li>\n<li>Qiu-Hui Lin, Chi-Wei Chen, Zeng-Wei Hong,* and Yen-Wei Chu* (2009) PredPhosGrid &#8211; A Grid-based Phosphorylation Prediction System by Reengineering off-the-shelf Bioinformatic Websites, Proceedings of the 20th Workshop on Object-Oriented Technology and Applications, pp. 1-6.<\/li>\n<li>Cheng-Yu Liao, Wei-Fu Lu and Yen-Wei Chu* (2009) Using Genetic Algorithms to Assist the Classification of Biological Documents: An Example of Mushroom and Toadstool Data, Information Management and Commerce Technology Conference, pp. 559, Yunlin, Taiwan.<\/li>\n<li>Yen-Wei Chu*, Chin-Sheng Yu. and Hui-Fuang Ng. (2008) Protein Secondary Structures Prediction Using Data Fusion Approach, Proceedings of the 7th IEEE World Congress on Intelligent Control and Automation (WCICA), v. 4, pp. 1885-1890. <span style=\"text-transform: uppercase;\"><b>(EI, <\/b><\/span> NSC 96-2218-E-468-001)<\/li>\n<li>Hui-Fuang Ng* and Yen-Wei Chu (2008) Illumination Invariant Color Model for Image Matching and Object Recognition, The Eighth International Conference on Intelligent Systems Design and Applications.<span style=\"text-transform: uppercase;\"><b>(EI)<\/b><\/span><\/li>\n<li>Yen-Wei Chu*, Chin-Sheng Yu., Chia-Hsiang Pai and You-Ting Wu (2007) Protein Phosphorylation Site Prediction Using Data Fusion Approach, National Computer Symposium, v1, pp. 1-8 (NSC 96-2218-E-468-001)<\/li>\n<li>Yen-Wei Chu*, Chin-Sheng Yu., Chih-Ying Chen and Kun-Chang Hsieh (2007) Applying Sequence Conservation Strategy to Predict Protein Phosphorylation Site, National Computer Symposium, v1, pp.9-15 (NSC 96-2218-E-468-001)<\/li>\n<li>Ting-Yi Chang*, Yi-Ting Chen, and Yen-Wei Chu (2007) &#8216;Develop the Peer Assessment of Cooperative Learning in e-Learning \u2014 Using Consistent Fuzzy Preference Relation, National Computer Symposium, pp. 554-561<\/li>\n<li>Hui-Fuang Ng*, Ding-Fu Wang and Yen-Wei Chu (2007) Illumination invariant color descriptors for image matching. The 20th IPPR Conference on Computer Vision, Graphics and Image Processing, Miaoli, Taiwan.<\/li>\n<li>Yen-Wei Chu* and Chuen-Tsai Sun (2006) A Hybrid Genetic Algorithm Approach for Protein Secondary Structures, Proceedings of the 6th IEEE World Congress on Intelligent Control and Automation (WCICA), v. 4, pp. 3320-3324. <span style=\"text-transform: uppercase;\"><span style=\"text-transform: uppercase;\"><b>(EI)<\/b><\/span><\/span><\/li>\n<li>Yen-Wei Chu*, Chuen-Tsai Sun, and Chung-Yuan Huang (2005) Finding Regularity in Protein Secondary Structures using a Cluster-based Genetic Algorithm. In Proceedings of International Conference on Computational Intelligence, Man-Machine Systems and Cybernetics (CIMMACS&#8217;05), Miami, Florida, USA, pp. 179-183. <span style=\"text-transform: uppercase;\"><b>(IEE, EI)<\/b><\/span><\/li>\n<li>Chung-Yuan Huang*, Chuen-Tsai Sun, and Yen-Wei Chu (2005) Using a Coevolution Mechanism with a Dyna Architecture for Parameter Adaptation in XCS Classifier Systems. In Proceedings of International Conference on Computational Intelligence, Man-Machine Systems and Cybernetics (CIMMACS&#8217;05), Miami, Florida, USA, pp. 173-178. <span style=\"text-transform: uppercase;\"><b>(IEE, EI)<\/b><\/span><\/li>\n<li>Yen-Wei Chu* and Chuen-Tsai Sun (2004) Regularity of secondary protein structures: A genetic algorithm approach, Proceedings of the 5th IEEE World Congress on Intelligent Control and Automation (WCICA), v. 3, pp. 2104-2108.<span style=\"text-transform: uppercase;\"><b>(EI)<\/b><\/span><\/li>\n<li>Chuen-Tsai Sun* and Yen-Wei Chu (1997) Hysteresis Behavior in Fuzzy Perception: A Preliminary Experiment. Second International ICSC Symposium on Intelligent Industrial Automation and Soft Computing, Nimes, France, Sep. 1997.<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5c08\u66f8\u8207\u5c08\u66f8\u8ad6\u6587<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li><span class=\"Span-Author\">Chu Y.W.<\/span>\u00a0(2006)\u00a0<i>Finding Protein Secondary Structure Regularity and Related Applications:<\/i>\u00a0National Chiao Tung University, Hsinchu, Taiwan.\u00a0<span style=\"text-transform: capitalize;\"><b>(Dissertation)<\/b><\/span><\/li>\n<li><span class=\"Span-Author\">Chu Y.W.<\/span>\u00a0(1998)\u00a0<i>Studies on Hysteresis: Human Perception and Time Series Prediction:<\/i>\u00a0National Chiao Tung University, Hsinchu, Taiwan.\u00a0<span style=\"text-transform: capitalize;\"><b>(Master Thesis)<\/b><\/span><\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div id=\"gtx-anchor\" style=\"position: absolute; visibility: hidden; left: 225.391px; top: 1037.8px; width: 563.578px; height: 19px;\"><\/div>\n<div class=\"jfk-bubble gtx-bubble\" style=\"visibility: visible; left: -182px; top: 1067px; opacity: 1;\" role=\"alertdialog\" aria-describedby=\"bubble-5\">\n<div id=\"bubble-5\" class=\"jfk-bubble-content-id\">\n<div id=\"gtx-host\" style=\"min-width: 200px; max-width: 400px;\"><\/div>\n<\/div>\n<div class=\"jfk-bubble-closebtn-id jfk-bubble-closebtn\" tabindex=\"0\" role=\"button\" aria-label=\"Close\"><\/div>\n<div class=\"jfk-bubble-arrow-id jfk-bubble-arrow jfk-bubble-arrowup\" style=\"left: 497.391px;\">\n<div class=\"jfk-bubble-arrowimplbefore\"><\/div>\n<div class=\"jfk-bubble-arrowimplafter\"><\/div>\n<\/div>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<ul class=\"team-manager-free-items-style2-social_media_team-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-teamprofiles-1739\">\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-title-1739\">\r\n\t\t\t\t\t\t\t\t<a href=\"\" data-featherlight=\"#fl1162905701\">\r\n\t\t\t\t\t\t\t\t\t\u6731\u5f65\u7152\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-post-1739\">\r\n\t\t\t\t\t\t\t\t\u6559\u6388\u517c\u6240\u9577\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<p style=\"display:block\" class=\"team-manager-free-items-style2-team-description-1739\">\r\n\t\t\t\t\t\t\t\t\u7814\u7a76\u65b9\u5411: Bioinformatics algorithms, Precision medicine, Intelligent agriculture, Big data analysis, Artificial intelligence\t\t\t\t\t\t\t<\/p>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t\t<div class=\"teamshowcasefree-col-lg-3 teamshowcasefree-col-md-2 teamshowcasefree-col-sm-2 teamshowcasefree-col-xs-1\">\r\n\t\t\t\t\t<div class=\"team-manager-free-items-style2-1739\">\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-pic-1739\">\r\n\t\t\t\t\t\t\t<a href=\"#\" data-featherlight=\"#fl11116381599\">\r\n\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/YingTsongChen.jpeg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t<div class=\"lightbox\" id=\"fl11116381599\">\r\n\t\t\t\t\t\t\t\t\t<div class=\"team_popup_container-1739\">\r\n\t\t\t\t\t\t\t\t\t\t<h2>\u9673\u76c8\u7481<\/h2>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area_img-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/YingTsongChen.jpeg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_contact_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\"><a href=\"mailto: onion@nchu.edu.tw\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\tonion@nchu.edu.tw<\/a><\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">(04)22840338 #7101(\u8fa6\u516c\u5ba4) #7111(\u5be6\u9a57\u5ba4)<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">\u52d5\u690d\u7269\u9632\u6aa2\u75ab\u5927\u6a137\u6a13711\u5ba4<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<ul class=\"team-manager-popup-items-social-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_right_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/orcid.org\/0000-0003-1337-4127\"><img loading=\"lazy\" class=\"wp-image-2595 alignright\" src=\"http:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png\" alt=\"\" width=\"79\" height=\"78\" srcset=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png 150w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-24x24.png 24w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-36x36.png 36w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-48x48.png 48w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948.png 190w\" sizes=\"(max-width: 79px) 100vw, 79px\" \/><\/a>\u7814\u7a76\u5ba4:<a href=\"https:\/\/megagenome.nchu.edu.tw\" target=\"_blank\" rel=\"noopener noreferrer\">\u5fae\u751f\u7269\u57fa\u56e0\u9ad4\u6838\u5fc3\u7814\u7a76\u5ba4<\/a><\/p>\n<h4>\u7c21\u8981\u7d93\u6b77<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"20%\">\u8077\u7a31<\/th>\n<th width=\"54%\">\u670d\u52d9\u55ae\u4f4d<\/th>\n<th width=\"26%\">\u8d77\u8a16\u5e74\u6708<\/th>\n<\/tr>\n<tr>\n<td>\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2022.08 &#8211;<\/td>\n<\/tr>\n<tr>\n<td>\u517c\u4efb\u526f\u7814\u7a76\u54e1<\/td>\n<td>\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662 \u5206\u5b50\u8207\u57fa\u56e0\u91ab\u5b78\u7814\u7a76\u6240<\/td>\n<td>2019.08-<\/td>\n<\/tr>\n<tr>\n<td>\u5408\u8058\u526f\u7814\u7a76\u54e1<\/td>\n<td>\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662 \u5206\u5b50\u8207\u57fa\u56e0\u91ab\u5b78\u7814\u7a76\u6240<\/td>\n<td>2018 &#8211; 2019<\/td>\n<\/tr>\n<tr>\n<td>\u526f\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2015.02 &#8211;\u00a02022.08<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2010.08 &#8211; 2015.01<\/td>\n<\/tr>\n<tr>\n<td>\u5408\u8058\u52a9\u7814\u7a76\u54e1<\/td>\n<td>\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u5206\u5b50\u8207\u57fa\u56e0\u91ab\u5b78\u7814\u7a76\u6240<\/td>\n<td>2011 &#8211; 2017<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2009 &#8211; 2010<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb\u5f8c\u7814\u7a76<\/td>\n<td>\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u5206\u5b50\u8207\u57fa\u56e0\u91ab\u5b78\u7814\u7a76\u7d44<\/td>\n<td>2004~2009<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb<\/td>\n<td>\u570b\u7acb\u4ea4\u901a\u5927\u5b78 \u751f\u7269\u79d1\u6280\u7cfb<\/td>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u69ae\u8b7d<\/h4>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" style=\"height: 129px;\" width=\"994\">\n<tbody>\n<tr>\n<th width=\"14%\">\u6642\u9593<\/th>\n<th width=\"86%\">\u5167\u5bb9<\/th>\n<\/tr>\n<tr>\n<td>2014<\/td>\n<td>\u4e2d\u8208\u5927\u5b78\u5091\u51fa\u9752\u5e74\u6559\u5e2b<\/td>\n<\/tr>\n<tr>\n<td>2015<\/td>\n<td>\u4e2d\u8208\u5927\u5b78104 \u5b78\uf98e\ufa01\u512a\uf97c\u901a\uf9fc\u6559\u5e2b<\/td>\n<\/tr>\n<tr>\n<td>2018<\/td>\n<td>\u4e2d\u8208\u5927\u5b78107\u5b78\u5e74\u5ea6\u512a\u8058\u6559\u5e2b<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u5b78\u8207\u7814\u7a76<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u7a76\u65b9\u5411<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>\u7d30\u83cc\u57fa\u56e0\u9ad4\u5b78<\/li>\n<li>\u529f\u80fd\u6027\u57fa\u56e0\u9ad4\u5b78<\/li>\n<li>\u6bd4\u8f03\u57fa\u56e0\u9ad4\u5b78<\/li>\n<li>\u8cea\u9ad4\u7814\u7a76<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u6388\u8ab2\u7a0b:<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u8ab2\u7a0b\u540d\u7a31<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\u751f\u7269\u5316\u5b78(\u5927\u5b78\u90e8\u5712\u85dd\u52d5\u79d1)<br \/>\n\u7d30\u80de\u751f\u7269\u5b78(\u5927\u5b78\u90e8\u751f\u6280\u5b78\u7a0b)<br \/>\n\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u5927\u5b78\u90e8\u751f\u79d1\u7cfb)<br \/>\n\u751f\u547d\u79d1\u5b78\u8207\u751f\u7269\u8cc7\u8a0a\u8da3\u8ac7(\u5927\u5b78\u901a\u8b58\u8ab2\u7a0b)<br \/>\n\u751f\u7269\u5316\u5b78(\u98df\u751f\u7cfb)<br \/>\n\u6563\u5f48\u69cd\u5b9a\u5e8f\u539f\u7406\u8207\u5be6\u7fd2(\u57fa\u8cc7\u6240)<br \/>\n\u529f\u80fd\u6027\u751f\u7269\u5b78(\u57fa\u8cc7\u6240)<br \/>\n\u751f\u91ab\u5927\u6578\u64da\u7279\u8ad6(\u4e00\u3001\u4e8c)(\u57fa\u8cc7\u6240)<br \/>\n\u5fae\u751f\u7269\u907a\u50b3\u8207\u57fa\u56e0\u9ad4\u7279\u8ad6(\u4e00\u3001\u4e8c)(\u57fa\u8cc7\u6240)<br \/>\n\u61c9\u7528\u57fa\u56e0\u9ad4\u5b78\u53ca\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u57fa\u8cc7\u6240)<br \/>\n\u5c08\u984c\u8a0e\u8ad6 (\u57fa\u8cc7\u6240)<br \/>\n\u5c08\u984c\u7814\u7a76E (\u91ab\u79d1\u5b78\u7a0b)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u8457\u4f5c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u671f\u520a\u8ad6\u6587 (\u2217Corresponding author)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>Huang CL, Chu HF, Wu CC, Deng FS, Wen PJ, Chien SP, Chao CH, Chen YT, Lu MK, Tsai TC*. Exopolysaccharide is the Potential Effector of Lactobacillus fermentum PS150, a Hypnotic Psychobiotic Strain. Front Microbial(2023)<\/li>\n<li>Cheng YH, Ko YC, Ku HJ, Huang CC, Yao YC, Liao YT, Chen YT, Huang SF, Huang LR*. Novel paired cell lines for the study of lipid metabolism and cancer stemness of hepatocellular carcinoma. Front Cell Dev Biol(2022)<\/li>\n<li>Lee YL, Liu KM, Chang HL, Liao YC, Lin JS, Kung FY, Ho CM, Lin KH,\u00a0Chen YT*. The evolutionary trend and genomic features of an emerging lineage of Elizabethkingia anophelis strains in Taiwan. Microbiol Spectr. 2022 [<a href=\"https:\/\/doi.org\/10.1128\/spectrum.01682-21\">online<\/a>]<\/li>\n<li>Hong YP, Wang YW, Chen BH, Song HY, Chiou CS,\u00a0Chen YT*. RamAp, an efflux pump regulator carried by an IncHI2 plasmid. Antimicrob Agents Chenother. 2021 [<a href=\"https:\/\/doi.org\/10.1128\/AAC.01152-21\">Epub ahead of print<\/a>]<\/li>\n<li>Hong YP, Chen YT, Wang YW, Chen BH, Teng RH, Chen YS, Chiou CS*. Integrative and conjugative element-mediated azithromycin resistance in multi drug-resistant Salmonella enterica serovar Albany. Antimicrob Agents Chemother. 2021 [<a href=\"https:\/\/aac.asm.org\/content\/65\/5\/e02634-20\">Epub ahead of print<\/a>]<\/li>\n<li>Lee YL, Liu KM, Chang HL, Lin JS, Kung FY, Ho CM, Lin KS,\u00a0Chen YT*. A dominant strain of Elizabethkingia anophelis emerged from hospital water system to cause a three-year outbreak in a respiratory care center. J Hosp Infect. 2021. 108:43-51. PubMed PMID33157171.<\/li>\n<li>Lu MC, Chen YT, Tang HL, Liu YY, Chen BH, Wang YW, Chen YS, Teng RH, Hong YP, Chiou CS, Chiang MK, Lai YC*. Transmission and evolution of OXA-48-producing\u00a0Klebsiella pneumoniae ST11 in a single hospital in Taiwan. J Antimicrob\u00a0Chemother. 2020 Feb 1;75(2):318-326. doi: 10.1093\/jac\/dkz431. PubMed PMID:31665400.<\/li>\n<li>Liu KM, Chang HL, Hsu MH, Lin YZ, Lee YL, Chen YT*. Complete Genome Sequencing of Elizabethkingia sp. Strain 2-6. Microbiol Resour Announc. 2019 Oct 31;8(44).\u00a0pii: e00805-19. doi: 10.1128\/MRA.00805-19. PubMed PMID: 31672739; PubMed Central PMCID: PMC6953514.<\/li>\n<li>Yao-Chen Wang, Hui-Ling Tang, Yu-Chieh Liao, Chien-Shun Chiou, Ying-Tsong Chen, Ming-Ko Chiang, Min-Chi Lu, and Yi-Chyi Lai :Co-carriage of distinct bla<sub>KPC-2<\/sub>and bla<sub>OXA-48<\/sub>\u00a0plasmids in a single ST11 carbapenem-resistant Klebsiella pneumoniae isolate. Antimicrobial Agents and Chemotherapy(2019)<\/li>\n<li>Dou HY, Lin CH, Chen YY, Yang SJ, Chang JR, Wu KM, Chen YT, Chin PJ, Liu YM, Su IJ, Tsai SF: Lineage-specific SNPs for genotyping of Mycobacterium tuberculosis clinical isolates. Scientific Reports(2017)<\/li>\n<li>Chiou CS, Chen YT, Wang YW, Liu YY, Kuo HC, Tu YH, Lin AC, Liao YS, Hong YP :Dissemination of mcr-1-Carrying Plasmids among Colistin-Resistant Salmonella Strains from Humans and Food-Producing Animals in Taiwan. Antimicrobial Agents and Chemotherapy(2017)<\/li>\n<li>Lu MC, Chen YT, Chiang MK, Wang YC, Hsiao PY, Huang YJ, Lin CT, Cheng CC, Liang CL, Lai YC: Colibactin contributes to the hyper virulence of pks+ K1 CC23 Klebsiella pneumoniae in mouse meningitis infections. Frontiers in Cellular and Infection Microbiology(2017)<\/li>\n<li>Chen YT, Lai YC, Tan MC, Hsieh LY, Wang JT, Shiau YR, Wang HY, Lin AC, Lai JF, Huang IW, Lauderdale TL: Prevalence and characteristics of pks genotoxin gene cluster-positive clinical Klebsiella pneumoniae isolates in Taiwan. Scientific Reports(2017)<\/li>\n<li>Horng-Yunn Dou, Yih-Yuan Chen, Ying-Tsong Chen, Jia-Ru Chang, Chien- Hsing Lin, Keh-Ming Wu, Ming-Shian Lin, Ih-Jen Su and Shih-Feng Tsai: Genomics Study of Mycobacterium tuberculosis Strains from Different Ethnic Populations in Taiwan. Evolutionary Bioinformatics(2016)<\/li>\n<li>Chen YT, Siu LK, Tsai YK, Lin FM, Koh TH, Chen JH: A Common Flanking Region in Promiscuous Plasmids Encoding blaNDM-1 in Klebsiella pneumoniae Isolated in Singapore. Microbial Drug Resistance(2016)<\/li>\n<li>Huang TW, Lauderdale TL, Liao TL, Hsu MC, Chang FY, Chang SC, Khong WX, Ng OT, Chen YT, Kuo SC, Chen TL, Mu JJ, Tsai SF: Effective transfer of a 47 kb NDM-1-positive plasmid among Acinetobacter species. Journal of Antimicrobial Chemotherapy(2015)<\/li>\n<li>Chang JW, Hou MM, Hsieh JJ, Cheung YC, Wang HM, Chen JS, Wang CH,Chen CH, Yeh KY, Ou LY, Hsieh CH, Wu HDI, Chen YT, Chang IC, Huang SF: Early radiographic response to epidermal growth factor receptor- tyrosine kinase inhibitor in non-small cell lung cancer patients with epidermal growth factor receptor mutations: A prospective study. Biomedical Journa(2015)<\/li>\n<li>Chen CJ, Wu TL, Chen YT, Fung CP, Chuang YC, Lin JC, and Siu LK: Closely related NDM-1-encoding plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan. PlosONE(2014)<\/li>\n<li>Tang HJ, Chen YT, Chiang T, Fung CP, Chuang YC, Siu LK: Identification of the first imported KPC-3 Klebsiella pneumoniae from the USA to Taiwan. International Journal of Antimicrobial Agents(2014)<\/li>\n<li>Lai YC, Lin AC, Chiang MK, Dai YH, Hsu CC, Lu MC, Liau CY, and Chen YT: Genotoxic Klebsiella pneumoniae in Taiwan. PlosONE(2014)<\/li>\n<li>Chen YT, Lin JC, Fung CP, Lu PL, Chuang YC, Wu TL, Siu LK: KPC-2-encoding plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan. Journal of Antimicrobial Chemotherapy<\/li>\n<li>Lai YC, Lin AC, Chiang MK, Dai YH, Hsu CC, Lu MC, Liau CY, and\u00a0<span class=\"Span-Author\">Chen YT*<\/span>. Genotoxic Klebsiella pneumoniae in Taiwan. PlosONE. 2014. 9:e96292.<\/li>\n<li><span class=\"Span-Author\">Chen YT*<\/span>, Lin JC, Fung CP, Lu PL, Chuang YC, Wu TL, Siu LK*. KPC-2-encoding plasmids from Escherichia coli and Klebsiella pneumoniae in Taiwan. Journal of Antimicrobial Chemotherapy. 2013. 69:628-631.<\/li>\n<li>Huang TW, Wang JT, Lauderdale TL, Liao TL, Lai JF, Tan MJ, Lin AC,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Tsai SF, Chang SC*. Complete sequences of two plasmids in an NDM-1 positive Klebsiella oxytoca isolated from Taiwan. Antimicrobial Agents and Chemotherapy. 2013. 57:4072-4076.<\/li>\n<li>Huang TW, Chen TL,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Lauderdale TL, Liao TL, Lee YT, Chen CP, Liu YM, Lin AC, Chang YH, Wu KM, Kirby R, Lai JF, Tan, MC, Siu, LK, Chang CM, Fung CP, Tsai SF. Copy Number Change of the NDM-1 Sequence in a Multidrug-Resistant Klebsiella pneumoniae Clinical Isolate. PlosONE. 2013. 8:e62774.<\/li>\n<li><span class=\"Span-Author\">Chen YT*<\/span>, Lin AC, Siu LK, Koh TH. Sequence of closely related plasmids encoding blaNDM-1 in two unrelated Klebsiella pneumoniae isolates in Singapore. PlosONE. 2012. 7:e48737.<\/li>\n<li>Lin AC, Liao TL, Lin YC, Lai YC, Lu MC,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>. Complete Genome Sequence of Klebsiella pneumoniae 1084, a Hypermucoviscosity-negative K1 Clinical Strain. Journal of Bacteriology. 2012. 194:6316.<\/li>\n<li>Liao TL, Chen SY, Lin AC, Huang TW, Lauderdale TL, Tsai SF, and\u00a0<span class=\"Span-Author\">Chen YT*<\/span>. Complete genome sequence of Klebsiella oxytoca E718, a New Delhi Metallo-beta-lactamase-1-producing nosocomial strain. Journal of Bacteriology. 2012. 194:5454.<\/li>\n<li>Huang SH, Wang CK, Peng HL, Wu CC,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Hong YM, and Lin CT. Role of the small RNA RyhB in the Fur regulon in mediating the capsular polysaccharide biosynthesis and iron acquisition systems in Klebsiella pneumoniae. BMC Microbiology. 2012. 12:148.<\/li>\n<li>Huang TW, Chen FJ, Miu WC, Liao TL, Lin AC, Huang IW, Wu KM, Tsai SF,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, and Lauderdale TL*. Complete Genome Sequence of Staphylococcus aureus M013, a pvl-positive ST59:SCCmec V Strain Isolated in Taiwan. Journal of Bacteriology. 2012. 194:1256-1257.<\/li>\n<li><span class=\"Span-Author\">Chen YT*<\/span>, Chang WC J, Liu HP, Yu TF, Chiu YT, Hsieh JJ, Chen YT, Chen YR, Wu I HD, Huang SF*. Clinical implications of high MET gene dosage in non-small cell lung cancer patients without prior tyrosine kinase inhibitor treatment. Journal of Thoracic Oncology. 2011. 6:2027-2035.<\/li>\n<li>Chang JR, Lin CH, Tsai SF, Su IJ, Tseng FC,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Chiueh TS, Sun JR, Huang TS, Chen YS, and Dou HR*. Genotypic analysis of genes associated with transmission and drug resistance in the Beijing lineage of Mycobacterium tuberculosis. Clinical Microbiology and Infection. 2011. 17:1391-1396.<\/li>\n<li>Hoang KC, Lai TH, Lin CS,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, and Liau CY*.The Chitinolytic Activities of Streptomyces sp. TH-11. International Journal of Molecular Sciences. 2011. 12:56-65.<\/li>\n<li>Liu HP, Wu HDI, Chang JWC, MD, Wu YC, Yang HY,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Hsieh WY, Chen YT, Chen YR, Huang SF*. Prognostic implications of EGFR and KRAS gene mutations, and EGFR gene copy numbers in Surgically Resectable Non-Small Cell Lung Cancer Patients in Taiwan. Journal of Thoracic Oncology. 2010. 5:1175-1184.<\/li>\n<li>Tang HL, Chiang MK, Liou WJ,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Peng HL, Chiou CS, Liu KS, Lu MC, Tung KC and Lai YC*. Correlation between Klebsiella pneumoniae carrying pLVPK-derived loci and abscess formation. European Journal of Clinical Microbiology &amp; Infectious Diseases. 2010. 29:689-698.<\/li>\n<li>Shu HY, Fung CP, Liu, YM, Wu, KM,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Li LH, Liu TT, Kirby R, and Tsai SF*. Genetic diversity of capsular polysaccharide biosynthesis in Klebsiella pneumoniae clinical isolates. Microbiology. 2009. 155:4170-4183.<\/li>\n<li>Wu KM, Li LH, Yan JJ, Tsao N, Liao TL, Tsai HC, Fung CP, Chen HJ, Liu YM, Wang JT, Fang CT, Chang SC, Shu HY, Liu TT,\u00a0<span class=\"Span-Author\">Chen YT*<\/span>, Shiau YR, Lauderdale TL, Su IJ, Kirby R* and Tsai SF. Genome Sequencing and Comparative Analysis of Klebsiella pneumoniae NTUH-K2044, a Strain Causing Liver Abscess and Meningitis. Journal of Bacteriology. 2009. 191:4492-4501.<\/li>\n<li><span class=\"Span-Author\">Chen YT*<\/span>, Liao TL, Liu YM, Lauderdale TL, Yan JJ, and Tsai SF. Mobilization of qnrB2 and ISCR1 in Plasmids. Antimicrobial Agents and Chemotherapy. 2009. 53:1235-1237.<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u8a0e\u6703\u8ad6\u6587 (*Invited speaker)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>YT Chen, CA Liao, XY Huang, AC Lin, TL Lauderdale: Identification and genomic analyses of an emerging virulent Klebsiella pneumoniae K62 clone in Taiwan. The 41th Annual Meeting of the Molecular Biology Society of Japan Yokohama\/Japan<\/li>\n<li>Ying-Tsong Chen, Tsai-Ling Lauderdale, Xin-Ying Huang, Ann-Chi Lin: Population genetics studies of Klebsiella pneumoniae genotoxic K62 type in Taiwan. 4th Annual Microbiology &amp; Infectious Diseases Asia Congress 7th Annual Next Generation Sequencing &amp; Clinical Diagnostics Asia Congress 5th Annual Single Cell Analysis Asia Congress Singapore<\/li>\n<li>Yu-Han Liu, Ann-Chi Li, Chun-Hong Chen, Ying-Tsong Chen: Genomics Studies on the Ae. albopictus mitochondria. IMGM Poster Day NHRI\/Taiwan<\/li>\n<li>XY Huang, AC Lin, TL Lauderdale, YT Chen: Complete Sequencing and Analyses of a Genotoxic Klebsiella pneumoniae K62 strain. 3rd Annual Microbiology &amp; Infectious Diseases Asia Congress \/ 6th Annual Next Generation Sequencing Asia CongressSingapore<\/li>\n<li>YT Chen: \u514b\u96f7\u767d\u6c0f\u80ba\u708e\u83cc\u7684\u57fa\u56e0\u9ad4\u5b78\u7814\u7a76(invited speech). 2016\u8fb2\u696d\u66a8\u751f\u7269\u8cc7\u8a0a\u5206\u6790\u524d\u77bb\u8207\u65b0\u77e5\u7814\u8a0e\u6703<\/li>\n<li>YT Chen: \u57fa\u56e0\u6bd2\u6027\u8207\u53f0\u7063\u7684\u514b\u96f7\u767d\u6c0f\u80ba\u708e\u83cc(invited speech). 2015\u7d30\u83cc\u5b78\u7814\u8a0e\u6703<\/li>\n<li>\u6d2a\u7fa9\u9594\uff0c\u9673\u76c8\u7481: \u514b\u96f7\u767d\u6c0f\u80ba\u708e\u687f\u83cc\u57fa\u56e0\u9ad4\u5c0f\u5cf6\u6a21\u7d44\u9593\u4ea4\u4e92\u4f5c\u7528\u8207\u529f\u80fd\u4e4b\u63a2\u8a0e. 2015\u7d30\u83cc\u5b78\u7814\u8a0e\u6703<\/li>\n<li>YT Chen: Genotoxic Klebsiella pneumoniae in Taiwan (invited speech). International Symposium on Evolutionary Genomics and Bioinformatics<\/li>\n<li>YT Chen: Functional Genomics Studies on Genotoxic Klebsiella pneumoniae in Taiwan (invited speech). 2014 Life Taiwan User Conference -The future of laboratory developed testing &#8211; The total solution powered by Roche<\/li>\n<li>TL Liao; TW Huang; KM Wu; CT Lee; YM Liu; AC Lin; YT Chen; TT Liu; N Bisharat; LI Hor; SF Tsai: A single chromosome of 5.2 Mb in Vibrio vulnificus biotype 3 strain CECT7356. IMGM Poster Day NHRI\/Taiwan<\/li>\n<li>YC Lai; AC Lin; YT Chen: Genotoxicity of Klebsiella pneumoniae in Taiwan. IMGM Poster Day NHRI\/Taiwan<\/li>\n<li>\u6d2a\u7fa9\u9594\uff0c\u9ec3\u610f\u771f\uff0c\u5f35\u8a60\u921e\uff0c\u8cf4\u6021\u742a\uff0c\u6797\u9756\u5a77\uff0c\u9673\u76c8\u7481: \u514b\u96f7\u767d\u6c0f\u80ba\u708e\u687f\u83cc\u57fa\u56e0\u9ad4\u5c0f\u5cf6KPHPI208\u7684\u529f\u80fd\u6027\u7814\u7a76. 2014\u7d30\u83cc\u5b78\u7814\u8a0e\u6703<\/li>\n<li>Genotoxicity of Klebsiella pneumoniae in Taiwan (2014) 2014 IMGM Poster Party, IMGM, NHRI, Taiwan<\/li>\n<li>A single chromosome of 5.2 Mb in Vibrio vulnificus biotype 3 strain CECT7356 (2014) IMGM Poster Party, IMGM, NHRI, Taiwan<\/li>\n<li>Complete genome sequence of Klebsiella pneumoniae 1084 and the identification of a genotoxin-encoding virulence genomic island (2013) 2013 IMGM Poster Party, IMGM, NHRI, Taiwan<\/li>\n<li>Missing pieces in Klebsiella pneumoniae genomes (2012) 2012\u7b2c\u5eff\u516b\u5c46\u751f\u7269\u590f\u4ee4\u71df<\/li>\n<li>Towards a database of antimicrobial resistance genes (2012) 2012 UST-UCSD I-RICE Symposium and Joint Biomedical Informatics Symposium between National Yang-Ming University (NYMU), and University of California, San Diego (UCSD)<\/li>\n<li>Using nalidixic acid-susceptibility and borderline resistance to identify plasmid-mediated quinolone resistance (PMQR) in Salmonella in Taiwan. (2012) 3rd ASM Conference on Antimicrobial Resistance in Zoonotic Bacteria and Foodborne Pathogens in Animals, Humans and the Environment, France. June 26-30.<\/li>\n<li>Multiplex sequencing of antimicrobial resistance genes by PGM. (2012) 3rd ASM Conference on Antimicrobial Resistance in Zoonotic Bacteria and Foodborne Pathogens in Animals, Humans and the Environment, France. June 26-30.<\/li>\n<li>Application of 454 in Bacterial Genomics (2012) \u751f\u7269\u8cc7\u8a0a\u7814\u7a76\u4e2d\u5fc3\u5b78\u8853\u7814\u8a0e\u6703 \u570b\u7acb\u4ea4\u901a\u5927\u5b78 (\u53d7\u9080\u6f14\u8b1b)<\/li>\n<li>Complete Sequencing and Annotation of Klebsiella oxytoca E718. (2012) \u8f49\u8b6f\u91ab\u5b78\u57fa\u56e0\u9ad4\u86cb\u767d\u8cea\u9ad4\u4e4b\u81e8\u5e8a\u61c9\u7528\u5b78\u8853\u7814\u8a0e, TaiChung, Taiwan. May 12.<\/li>\n<li>Missing Pieces in Klebsiella pneumoniae genomes. (2012) \u8f49\u8b6f\u91ab\u5b78\u57fa\u56e0\u9ad4\u86cb\u767d\u8cea\u9ad4\u4e4b\u81e8\u5e8a\u61c9\u7528\u5b78\u8853\u7814\u8a0e, TaiChung, Taiwan. May 12.<\/li>\n<li>Complete Sequencing and Annotation of MRSA strain M013 from Taiwan. (2012) \u8f49\u8b6f\u91ab\u5b78\u57fa\u56e0\u9ad4\u86cb\u767d\u8cea\u9ad4\u4e4b\u81e8\u5e8a\u61c9\u7528\u5b78\u8853\u7814\u8a0e, TaiChung, Taiwan. May 12.<\/li>\n<li>Comparative analysis of three NDM-1 positive plasmids using personal sequencers. (2012) 2012 NHRI Research Day, Zhunan, Taiwan. March 22.<\/li>\n<li>\u907a\u5931\u7684\u514b\u96f7\u767d\u6c0f\u687f\u83ccDNA\u5e8f\u5217 (2011) 2011\u5e74\u514b\u96f7\u767d\u6c0f\u687f\u83cc\u5b78\u8853\u7814\u8a0e\u6703 \u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u611f\u67d3\u75c7\u8207\u75ab\u82d7\u7814\u7a76\u6240\u8207\u570b\u9632\u91ab\u5b78\u9662 (\u53d7\u9080\u6f14\u8b1b)<\/li>\n<li>PMQR in Taiwan (2010) \u7cfb\u7d71\u751f\u7269\u5b78\u7814\u8a0e\u6703 \u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662 (\u5c08\u984c\u6f14\u8b1b)<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<ul class=\"team-manager-free-items-style2-social_media_team-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-teamprofiles-1739\">\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-title-1739\">\r\n\t\t\t\t\t\t\t\t<a href=\"\" data-featherlight=\"#fl11116381599\">\r\n\t\t\t\t\t\t\t\t\t\u9673\u76c8\u7481\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-post-1739\">\r\n\t\t\t\t\t\t\t\t\u6559\u6388\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<p style=\"display:block\" class=\"team-manager-free-items-style2-team-description-1739\">\r\n\t\t\t\t\t\t\t\t\u7814\u7a76\u65b9\u5411:Microbial Genomics,Functional Genomics,Comparative Genomics,Plasmids\t\t\t\t\t\t\t<\/p>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t\t<div class=\"teamshowcasefree-col-lg-3 teamshowcasefree-col-md-2 teamshowcasefree-col-sm-2 teamshowcasefree-col-xs-1\">\r\n\t\t\t\t\t<div class=\"team-manager-free-items-style2-1739\">\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-pic-1739\">\r\n\t\t\t\t\t\t\t<a href=\"#\" data-featherlight=\"#fl12140390717\">\r\n\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_ChenYuTing-new-1.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t<div class=\"lightbox\" id=\"fl12140390717\">\r\n\t\t\t\t\t\t\t\t\t<div class=\"team_popup_container-1739\">\r\n\t\t\t\t\t\t\t\t\t\t<h2>\u9673\u7389\u5a77<\/h2>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area_img-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_ChenYuTing-new-1.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_contact_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\"><a href=\"mailto: yuting@dragon.nchu.edu.tw\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\tyuting@dragon.nchu.edu.tw<\/a><\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">(04)22840338 #7021(\u8fa6\u516c\u5ba4) #7151(\u5be6\u9a57\u5ba4)<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">\u52d5\u690d\u7269\u9632\u6aa2\u75ab\u5927\u6a137\u6a13702\u5ba4<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<ul class=\"team-manager-popup-items-social-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_right_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<h4><a href=\"https:\/\/orcid.org\/0000-0003-4579-6498\"><img loading=\"lazy\" class=\"wp-image-2595 alignright\" src=\"http:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png\" alt=\"\" width=\"79\" height=\"79\" srcset=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png 150w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-24x24.png 24w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-36x36.png 36w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-48x48.png 48w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948.png 190w\" sizes=\"(max-width: 79px) 100vw, 79px\" \/><\/a>\u69ae\u8b7d<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"14%\">\u6642\u9593<\/th>\n<th width=\"86%\">\u5167\u5bb9<\/th>\n<\/tr>\n<tr>\n<td>2001<\/td>\n<td>\u7b2c\u5341\u516d\u5c46\u751f\u7269\u91ab\u5b78\u806f\u5408\u5e74\u6703\u751f\u7269\u5316\u5b78\u53ca\u5206\u5b50\u751f\u7269\u5b78\u5b78\u6703\u6700\u4f73\u58c1\u5831\u8ad6\u6587\u734e<\/td>\n<\/tr>\n<tr>\n<td>2000<\/td>\n<td>\u7b2c\u4e8c\u5c46\u4e2d\u7814\u9662\u690d\u7269\u6240\u58c1\u5831\u5c55\u512a\u7b49\u58c1\u5831\u8ad6\u6587\u734e<\/td>\n<\/tr>\n<tr>\n<td>2015<\/td>\n<td>\u4e2d\u8208\u5927\u5b78104\u5b78\u5e74\u5ea6\u670d\u52d9\u7279\u512a\u6559\u5e2b<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u7c21\u8981\u7d93\u6b77<\/h4>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"20%\">\u8077\u7a31<\/th>\n<th width=\"55%\">\u670d\u52d9\u55ae\u4f4d<\/th>\n<th width=\"25%\">\u8d77\u8a16\u5e74\u6708<\/th>\n<\/tr>\n<tr>\n<td>\u7d44\u9577<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3\u670d\u52d9\u63a8\u5ee3\u7d44<\/td>\n<td>2023\/08 &#8211; 2024\/07<\/td>\n<\/tr>\n<tr>\n<td>\u526f\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240<\/td>\n<td>2019\/08-present<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u5b78\u7814\u7a76\u6240<\/td>\n<td>2013\/03-2019-07<\/td>\n<\/tr>\n<tr>\n<td>\u7d44\u9577<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3\u670d\u52d9\u63a8\u5ee3\u7d44<\/td>\n<td>2008\/08 &#8211; 2009-03<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3<\/td>\n<td>2008\/08 &#8211; 2009-03<\/td>\n<\/tr>\n<tr>\n<td>\u5c08\u6848\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3<\/td>\n<td>2006\/08 &#8211; 2008\/07<\/td>\n<\/tr>\n<tr>\n<td>\u517c\u4efb\u52a9\u7406\u6559\u6388<\/td>\n<td>\u9192\u543e\u6280\u8853\u5b78\u9662\u901a\u8b58\u6559\u80b2\u4e2d\u5fc3<\/td>\n<td>2005\/09 &#8211; 2006\/06<\/td>\n<\/tr>\n<tr>\n<td>\u8a2a\u554f\u5b78\u8005<\/td>\n<td>\u7f8e\u570b\u8fb2\u696d\u90e8<\/td>\n<td>2005\/03 &#8211; 2005\/08<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb\u5f8c\u7814\u7a76\u54e1<\/td>\n<td>\u4e2d\u592e\u7814\u7a76\u9662\u690d\u7269\u66a8\u5fae\u751f\u7269\u7814\u7a76\u6240<\/td>\n<td>2003\/03 &#8211; 2006\/07<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb<\/td>\n<td>\u570b\u9632\u91ab\u5b78\u5927\u5b78 \u751f\u547d\u79d1\u5b78\u7814\u7a76\u6240<\/td>\n<td>1995\/08 &#8211; 2003\/02<\/td>\n<\/tr>\n<tr>\n<td>\u78a9\u58eb<\/td>\n<td>\u5927\u540c\u5927\u5b78 \u5316\u5b78\u5de5\u7a0b\u7814\u7a76\u6240<\/td>\n<td>1993\/09 &#8211; 1995\/06<\/td>\n<\/tr>\n<tr>\n<td>\u5b78\u58eb<\/td>\n<td>\u5927\u540c\u5927\u5b78 \u751f\u7269\u5de5\u7a0b\u7cfb<\/td>\n<td>1989\/09 &#8211; 1993\/06<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u5b78\u8207\u7814\u7a76<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u7a76\u65b9\u5411<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>\u5206\u5b50\u751f\u7269\u5b78<\/li>\n<li>\u690d\u7269\u57fa\u56e0\u8f49\u6b96<\/li>\n<li>\u690d\u7269\u529f\u80fd\u6027\u57fa\u56e0\u9ad4\u5b78<\/li>\n<li>\u751f\u7269\u80fd\u6e90<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u6388\u8ab2\u7a0b:<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u8ab2\u7a0b\u540d\u7a31<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\n<p class=\"pHead\">\u751f\u7269\u5316\u5b78(\u8fb2\u8cc7\u9662)\u3001\u751f\u7269\u5316\u5b78\u5be6\u7fd2(\u8fb2\u8cc7\u9662)\u3001\u61c9\u7528\u57fa\u56e0\u9ad4\u5b78\u53ca\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u57fa\u8cc7\u6240)\u3001\u9032\u968e\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u57fa\u8cc7\u6240)\u3001\u8cc7\u8a0a\u8207\u751f\u7269(\u57fa\u8cc7\u6240)\u3001\u690d\u7269\u57fa\u56e0\u9078\u6b96\u6280\u8853(\u751f\u6280\u78a9)\u3001\u690d\u7269\u57fa\u56e0\u8f49\u6b96\u7279\u8ad6(\u57fa\u8cc7\u6240)\u3001\u57fa\u56e0\u9ad4\u8cc7\u6599\u5eab\u5efa\u69cb\u8207\u5206\u6790(\u57fa\u8cc7\u6240)\u3001\u529f\u80fd\u6027\u57fa\u56e0\u9ad4\u5b78(\u57fa\u8cc7\u6240)\u3001\u8102\u80aa\u751f\u7269\u6280\u8853\u7279\u8ad6(\u57fa\u8cc7\u6240)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u8457\u4f5c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u671f\u520a\u8ad6\u6587 (*Corresponding author)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>Lin CT, Lin MT, <strong>Chen<\/strong> <strong>YT<\/strong> and Shaw JF*. (1995) The gene structure of Cu\/Zn-superoxide dismutase from sweet potato. Plant Physiol. 108: 827-828. (SCI)<\/li>\n<li>Lin CT, Lin MT, <strong>Chen<\/strong> <strong>YT<\/strong> and Shaw JF* (1995) Subunit interaction enhances enzyme activity and stability of cytosolic Cu-Zn-superoxide dismutase. Plant Mol. Biol. 28: 303-311. (SCI)<\/li>\n<li><strong>Chen YT<\/strong>, Lee IR, Yang CY, Wang YT, Yang SF, and Shaw JF* (2003) A novel papaya 1-aminocyclopropane-1-carboxylate oxidase gene<em> (CP-ACO2) <\/em>associated with late-stage senescence. Plant Science 164:531-540. (SCI)<\/li>\n<li>Yang CY, Chu FH, Wang YT, <strong>Chen YT<\/strong>, Yang SF, and Shaw JF* (2003) Novel broccoli 1-aminocyclopropane-1-carboxylate oxidase gene (<em>Bo-ACO3<\/em>) associated with the late stage of postharvest floret senescence. J. Agric. Food Chem. 51:2569-2575. (SCI)<\/li>\n<li>Chen LFO, Huang JY, Wang YH, <strong>Chen YT<\/strong> and Shaw JF* (2004) Ethylene insensitive and post-harvest yellowing retardation in mutant ethylene response sensor (<em>boers<\/em>) gene transformed broccoli (<em>Brassica olercea<\/em> italica) Mol. Breed. 14:199-213. (SCI)<\/li>\n<li>Wang YT, Yang CY, <strong>Chen YT<\/strong>, Lin Y and Shaw JF* (2004) Characterization of senescence-associated proteases in postharvest broccoli florets. Plant Physiol. Biochem. 42:663-670. (SCI)<\/li>\n<li><strong>Chen YT, <\/strong>Hsu LH, Huang IP, Tsai TC, Lee GC, and Shaw JF* (2007) Gene Cloning and characterization of a novel recombinant antifungal chitinase from Papaya (<em>Carica papaya<\/em>) Agric. Food Chem. 55:714-722. (SCI)<\/li>\n<li>Lee LC, <strong>Chen YT<\/strong>, Yen CC, Chiang TCY, Tang SJ, Lee GC* and Shaw JF* (2007) Altering the substrate specificity of <em>Candida rugosa<\/em> LIP4 by engineering the substrate binding sites. J. Agric. Food Chem. 55(13); 5103-5108. (SCI)<\/li>\n<li><strong>Chen<\/strong> <strong>YT, <\/strong>Chen HH, Uchimiya H, Chu MJ, Chiou YS, Shaw JF, Huang LC* (2007) Prolonging the longevity of <em>Cymbidium<\/em> flowers through genetic transformation. Acta Horticulture. 738: 545-548.<\/li>\n<li><strong>Chen YT<\/strong>, Chen LFO, Shaw JF* (2008) Senescence associated genes in harvested broccoli florets, Plant Science 175, 137-144. (SCI)<\/li>\n<li>Liau YJ,<strong> Chen YT<\/strong>, Lin CY, Huang JK, Lin CT* (2010) Characterisation of 2-Cys peroxiredoxin isozyme (Prx1) from <em>Taiwanofungus camphorata <\/em>(Niu-chang-chih): Expression and enzyme properties. Food Chem. 119: 154-160. (SCI)<\/li>\n<li><strong>Chen YT<\/strong>, Fang QS, Chiang CH, Yeh SD, Wu HW, Yu TA* (2010) Transgenic <em>Eustoma grandiflorum<\/em> expressing the bar gene are resistant to herbicide Basta\u00ae. PCTOC: J Plant Biotech. 102 (3): 347-356. (SCI)<\/li>\n<li>Chang IF, Chen PJ, Shen CH, Hsieh TJ, Hsu YW, Huang BL, Kuo CI, <strong>Chen YT<\/strong>, Chu HA, Yeh KW*, Huang LC* (2010) Proteomic profiling of proteins associated with the rejuvenation of <em>Sequoia sempervirens<\/em> (D. Don) Endl. Proteome Science 8:64. (SCI)<\/li>\n<li>Chuang HH, Chen PT, Wang WN, <strong>Chen YT<\/strong>*, Shaw JF* (2011) Functional proteomic analysis of rice bran esterases\/lipases and characterization of a novel recombinant esterase. J Agric Food Chem. 59(5):2019-25 (SCI)<\/li>\n<li>Chang PC, Pan WJ, Chen CW, <strong>Chen YT<\/strong> and Chu YW* (2012) DEsi: A design engine of siRNA that integrates SVMs prediction and feature filters. Biocat Agric Biotech 1: 129-134.<\/li>\n<li>Huang LC, Hsiao LJ, Pu SY, Kuo CI, Huang BL, Tseng TC, Huang HJ*, <strong>Chen YT*<\/strong> (2012) DNA Methylation and genome rearrangement characteristics of Phase change in cultured shoots of <em>Sequoia sempervirens<\/em>. Physiologia Plantarum 145: 360-368. (SCI)<\/li>\n<li>Chu HA, Chang IF, Shen CH, <strong>Chen YT<\/strong>, Wang HT, Li-Chun Huang LC*, and Yeh KW* (2012) Photosynthetic properties and photosystem stoichiometry of in vitro-grown juvenile, adult, and rejuvenated <em>Sequoia sempervirens <\/em>(D. Don) Endl. Botanical Studies. 53:3.1 (SCI)<\/li>\n<li>Chen PT, Chiang CJ, <strong>Chen YT<\/strong>, Lin HC, Liu CH, Chao YP*, Shaw JF*. (2012) Strategy for stable and high-level expression of recombinant trehalose synthase in <em>Escherichia coli<\/em>. J Agric Food Chem. 60 (23), 6063\u20136068 (SCI)<\/li>\n<li>Ko CY, Lai YL, Liu WY, Lin CH, <strong>Chen YT,<\/strong> Chen LF, Lin TY*, Shaw JF*. (2012) Arabidopsis ENDO2: Its catalytic role and requirement of N-glycosylation for function. J Agric Food Chem. 60 (20), 5169\u20135179 (SCI)<\/li>\n<li><strong><u>Chen YT<\/u><\/strong><strong>, <\/strong>Shen CH, Lin WD, Chu HA, Huang BL, Kuo CI, Yeh KW*, Huang LC*, and Chang IF* (2013) Small RNAs of <em>Sequoia sempervirens<\/em> during rejuvenation and phase change. Plant Biology 15(1):27-36 (SCI)<\/li>\n<li><strong>Chen YT<\/strong>, Wen L, Ho KC, Juang RH and Lin CT* (2013) Lemon protein disulfide isomerase: cDNA cloning and biochemical characterization. Botanical Studies 2013, 54:34. (SCI)<\/li>\n<li>Chuang HH, Cheng CY, Chen YT*, Shaw JF* (2014). Novel Highly Active Recombinant Glutaredoxin from Chlorella sorokiniana T-89. Journal of Agricultural and Food Chemistry, 62(4),927-933. (SCI).<\/li>\n<li>Huang CY#, Chen YT#, Wen L#, Sheu DC, Lin CT* (# contributed equally) (2014). A peroxiredoxin cDNA from Taiwanofungus camphorata: role of Cys31 in dimerization. Molecular Biology Reports, 41(1),155-164. (SCI).<\/li>\n<li>YT Chen, PF Hong, L Wen, CT Lin* (2014). Molecular cloning and characterization of a thioredoxin from Taiwanofungus camphorata. Botanical Studies, 55, 77. (SCI).<\/li>\n<li>Liu CH, Chen YT, Hou MH, Hu NJ, Chen CS* and Shaw JF* (2018) Crystallographic analysis of the Staphylococcus epidermidis lipase involved in esterification in aqueous solution. Acta Crystallographica Section F74, 351-354. (SCI) (First published: 05 June 2018) (IF=0.989, 21\/26) MOST 104-2313-B-005-007-MY2.<\/li>\n<li>Jian-Rong Li, Chun-Chi Liu, Chuan-Hu Sun, Yu-Ting Chen* (2018, Dec). Plant Stress RNA-seq Nexus: a stress-specific transcriptome database in plant cells. <em>BMC Genomics<\/em>, 19:966. (SCI). MOST 106-2311-B-005-005. \u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005.<\/li>\n<li>Yu Ting Chen, Chi Chang Chang, Chi\u2010Wei Chen, Kuan\u2010Chun Chen, Yen\u2010Wei Chu (2019, Jan). MADS\u2010Box Gene Classification in Angiosperms by Clustering and Machine Learning Approaches. <em>Frontiers in Genetics<\/em>, 9:707. (SCI). DOI: 10.3389\/fgene.2018.00707 MOST 106-2221-E-005-077-MY2. \u672c\u4eba\u70ba\u7b2c\u4e00\u4f5c\u8005<\/li>\n<li>Chen PT, Liu CH, Chen YT, Hsu FY, Shaw JF (2020, Jan). Isolation, Expression and Characterization of the Thermophilic Recombinant Esterase from <em>Geobacillus thermodenitrificans<\/em> <em>Appl Biochem Biotechnol<\/em>, 191(1):112-124. doi: 10.1007\/s12010-020-03225-w. MOST 106-2313-B-005-035-MY<\/li>\n<li>Chu YW, Chien CH, Sung MI, Chen CW, Chen YT* (2020, Jun) dBMHCC: A comprehensive hepatocellular carcinoma (HCC) biomarker database provides a reliable prediction system for novel HCC phosphorylated biomarkers. PLoS ONE 15(6): e0234084. https:\/\/doi.org\/10.1371\/journal.pone.0234084<\/li>\n<li>Zeng WW, Chen TC, Liu CH, Wang SY, Shaw JF and Chen YT* (2021 Apr) Identification and Isolation of an Intermediate Metabolite with Dual Antioxidant and Anti-Proliferative Activity Present in the Fungus Antrodia cinnamomea Cultured on an Alternative Medium with <em>Cinnamomum kanehirai<\/em> Leaf Extract. Plants (Basel). 10(4): 737. doi: 10.3390\/plants10040737 (corresponding author)<\/li>\n<li>Chen YT, Yang TH, Yu TA*.\u00a0(2023 May) <em>Ex vitro<\/em>rooting of minicutting of\u00a0<em>Carica papaya<\/em> single shoot from tissue culture.\u00a0<em>In Vitro Cell. Dev. Biol.-Plant<\/em>\u00a0<strong>59<\/strong>, 393\u2013400. <a href=\"https:\/\/doi.org\/10.1007\/s11627-023-10344-6\">https:\/\/doi.org\/10.1007\/s11627-023-10344-6<\/a>. (first author)<\/li>\n<li>Lin SH, Chien CH, Chang KP, Lu MF, Chen YT*, Chu YW* (2023 Jul) SaBrcada: Survival Intervals Prediction for Breast Cancer Patients by Dimension Raising and Age Stratification. Cancers (Basel) 20;15(14):3690. doi: 10.3390\/cancers15143690. (corresponding author)<\/li>\n<li>Yong ZL, <strong>Chen YT<\/strong>, Chan C*, Lee GC* (October 4, 2024) Enzymatic Production of Trehalose and Trehalulose by Immobilized Thermostable Trehalose Synthase. J. Agric. Food Chem. 2024, 72(41), 22745\u201322752 (second author)<\/li>\n<li>Kung SP, Umbreen H, Wang JH, Tsia CM, Lin TCC*, Chen YT* (2025 Jun) Cucurbitacin B inhibits Th17 cell differentiation via the suppression of the JAK\/STAT pathway and alleviates collagen-induced arthritis in mice. International Journal of Immunopathology and Pharmacology Volume 39, 1\u201317. doi: 10.1177\/03946320251348715.<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5b78\u8853\u7814\u8a0e\u6703\u8ad6\u6587 (*Invited speaker)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li><strong>Chen YT<\/strong> and Lin CT (1995) Purification and characterization of two isozymes of Cu\/Zn-SOD from sweet potato tuberous root.\u8fb2\u5316\u5b78\u6703\u7b2c\u4e09\u5341\u4e09\u6b21\u5927\u6703\u8ad6\u6587\u5ba3\u8b80\uff0c1995\u3002<\/li>\n<li><strong>Chen YT<\/strong> and Lin CT (1995) Cloning and structure analysis of Cu\/Zn-SOD gene from sweet potato. \u8fb2\u5316\u5b78\u6703\u7b2c\u4e09\u5341\u4e09\u6b21\u5927\u6703\u8ad6\u6587\u5ba3\u8b80\uff0c1995\u3002<\/li>\n<li><strong>Chen YT<\/strong> and Lin CT (1995) Over expression of sweet potato cytosolic Cu\/Zn-SOD in <em> coli<\/em>. \u8fb2\u5316\u5b78\u6703\u7b2c\u4e09\u5341\u4e09\u6b21\u5927\u6703\u8ad6\u6587\u5ba3\u8b80\uff0c1995\u3002<\/li>\n<li>Yang CY, Lin Y, Chu FH, <strong>Chen YT, <\/strong>Lee YR, Shaw JF (2000) Senescemce associated genes of broccoli florets. Symposium on Plant Sciences for 21<sup>st<\/sup> B5. pp34. Nov. 9-10, Taipei, Taiwan.<\/li>\n<li><strong>Chen<\/strong> <strong>YT, <\/strong>Lee IR, Yang CY, Shaw JF (2000) Differential expression of the papaya 1-aminocyclopropane-1-carboxylate oxidase gene family. Symposium on Plant Sciences for 21<sup>st<\/sup> C10. pp56. Nov. 9-10, Taipei, Taiwan.<\/li>\n<li><strong>Chen<\/strong> <strong>YT <\/strong>and Shaw JF (2001) (Invited lecture) Papaya ACC oxidases. The 2<sup>nd<\/sup> Internationtional Symposium on Biotechnology of Tropical and Subtropical Species. Nov. 5-9.Taipei, Taiwan.<\/li>\n<li><strong>Chen<\/strong> <strong>YT, <\/strong>Lee IR, Yang CY, Shaw JF (2001) Differential expression of the 1-aminocyclopropane-1-carboxylate oxidase gene family of papaya. \u7b2c\u5341\u516d\u5c46\u751f\u7269\u91ab\u5b78\u806f\u5408\u5e74\u6703\u751f\u7269\u5316\u5b78\u53ca\u5206\u5b50\u751f\u7269\u5b78\u5b78\u6703\u58c1\u5831\u8ad6\u6587 P99, Mar, 24-25, Taipei, Taiwan\u3002<\/li>\n<li><strong>Chen<\/strong> <strong>YT, <\/strong>Chou TL, Yang CY, Kao CY, Lai HY, Jian WT, Shaw JF (2003) Papaya fruit maturation and ripening associated gene. International Symposium on Plant Functional Genomics. A17, Nov 17-19, Taipei, Taiwan.<\/li>\n<li><strong>Chen<\/strong> <strong>YT, <\/strong>Chou TL, Yang CY, Kao CY, Lai HY, Jian WT, Shaw JF (2004) (Invited oral presentation) Papaya fruit maturation and ripening associated gene. International Symposium on Plant Functional Genomics. WA-06, June 6-11, Verona, Italy.<\/li>\n<li><strong>Chen<\/strong> <strong>YT<\/strong> (2005) (Invited speech) Papaya fruit maturation and ripening associated gene. April 19, USDA, Beltsville, USA.<\/li>\n<li><strong>Chen<\/strong> <strong>YT, <\/strong>Chen HH, Uchimiya H, Chu MJ, Chiou YS, Shaw JF, Huang LC (2005) (Invited oral presentation) Prolonging the longevity of <em>Cymbidium<\/em> flowers through genetic transformation. Proceeding of ISHS on the 3<sup>rd<\/sup> International Symposium on Biotechnology of Temperate Fruit Crops and Tropic species. October 10-14, USA.<\/li>\n<li><strong>Chen YT, <\/strong>Huang IP, Shu LH, Shaw JF (2006) Cloning and characterization of ethylene-upregualted chitinase from papaya. 7<sup>th<\/sup> International Symposium on the Plant Hormone Ethylene. June 18-22, Pisa, Italy.<\/li>\n<li>Chou YF, Chen HH, <strong>Chen YT,<\/strong> Shaw JF (2006) (Invited oral presentation) Molecular characterization of three broccoli chloropyllase genes, differentially regulated by ethylene. 7<sup>th<\/sup> International Symposium on the Plant Hormone Ethylene. June 18-22, Pisa, Italy.<\/li>\n<li><strong>Chen YT<\/strong> and Shaw JF (2007) (Invited Speech) The Application of Functional Genomics Study on Papaya and Its Implication in Fruit Industry. The International Symposium on Bio-industry Development and Post-graduate Workshop, Dec. 4-7, Taichung, Taiwan<\/li>\n<li><strong>Chen YT<\/strong>, Hsu LH, Huang IP, and Shaw JF (2007) A Novel Recombinant Antifungal Chitinase (CpCHI) from Papaya (<em>Carica papaya<\/em>). 3<sup>rd<\/sup> Internatrional Symposium on Biocatalysis and Biotechnology. Nov. 28-30, Taichung, Taiwan<\/li>\n<li>Lee LC, <strong>Chen YT<\/strong>, Yen CC, Tang SJ, Lee GC and Shaw JF (2007) Altering the Substrate Specificity of <em>Candida rugosa<\/em> LIP4 by Engineering the Substrate-Binding Sites. 3<sup>rd<\/sup> Internatrional Symposium on Biocatalysis and Biotechnology. Nov. 28-30, Taichung, Taiwan<\/li>\n<li><strong>YT Chen <\/strong>and Shaw JF (2007) (Organizer and Invited Speech) Papaya functional genomics and biotechnological application. 3<sup>rd<\/sup> Internatrional Symposium on Biocatalysis amd Biotechnology. Nov. 28-30, Taichung, Taiwan<\/li>\n<li><strong>Chen<\/strong> <strong>YT<\/strong> and Shaw JF (2007) (Invited Speech) Functional genes and biotechenology. The Sixth Cross-Strait Symposium on Plant Molecular Biology and Biotechnology. Jul. 3-7, Hong Kong, China<\/li>\n<li><strong>Chen YT<\/strong> and Shaw JF (2008) (Invited lecture) NCHU\/CUHK Bilateral Symposium on Plant Biotechnology. Dec 17-23, Taichung, Taiwan.<\/li>\n<li>Bezirganoglu I, <strong>Chen YT<\/strong>, Chang YL, Shaw JF* (2009) Melon transformation using antifungal protein &amp; chitinase gene to against fungal disease <em>Rhizoctania Solani.<\/em> The 5<sup>th<\/sup> International Symposium on Biocatalysis and Biotechnology. Taiwan. Nov 18-20. (Excellent Poster Award)<\/li>\n<li>Chuang HH, <strong>Chen YT*<\/strong>, Shaw JF* (2010) (Invited lecture) Characterization and application of the recombinant rice bran lipase. 2010 Lipid Science Division Symposium at the Annual Meeting of Korean Society of Food Science and Technology. Inchon, Korea. Jun 16-18.<\/li>\n<li>Yu TA, <strong>Chen YT*<\/strong>, Chiang CH, Wang PT, Chang YL, Shih HD, Yeh SD, Shaw JF* (2010) (Invited lecture) Transgenic melon plants expressing antifungal AFP3 protein develop resistance to fungal diseases. The 6<sup>th<\/sup> International Symposium on Biocatalysis and Biotechnology. Seoul, Korea. Nov 17-19.<\/li>\n<li>Bezirganoglu I, <strong>Chen YT<\/strong>, Chuang HH, Hwang SY, Shaw JF* (2010) Improve the resistance to <em>Rhizoctonia solani<\/em> of transgenic melon (<em>Cucumis melo<\/em> silver light L.) plants with overexpressing chitinases. The 6<sup>th<\/sup> International Symposium on Biocatalysis and Biotechnology. Seoul, Korea. Nov 17-19.<\/li>\n<li>Chuang HH, <strong>Chen YT<\/strong><strong><sup>\uff0a<\/sup><\/strong> and Shaw JF (2011) (Invited lecture) Functional proteomic analysis and characterization of a novel rice bran esterases\/lipases. The 7<sup>th<\/sup> International Symposium on Agricultural Biocatalysis and Biotechnology. Kyoto, Japan. Oct 10-13.<\/li>\n<li>Shaw JF* and <strong>Chen YT<\/strong> (2012) (Keynote Lecture) Biocatalysis in Agricultural Biotechnology. BIT\u2019s 3rd Inaugural Symposium on Enzymes &amp; Biocatalysis-2012 (SEB-2012), Xi&#8217;an, China. April, 25-28.<\/li>\n<li>Chuang HH, Cheng CY, Lee JH, Liu CH, Shaw JF and Chen YT* (2012) (Invited Lecture) Structure and functional study on <em>Chlorella sorokiniana<\/em> The 8<sup>th<\/sup> International Symposium on Agricultural Biocatalysis and Biotechnology. Sonoma Valley, CA, USA. Oct, 28-31.<\/li>\n<li>Chuang HH, Liu CH, <strong>Chen YT<\/strong><strong><sup>\uff0a<\/sup><\/strong>and Shaw JF (2012) (Invited Lecture) Study rice estersaes\/lipases by functional proteomics approach. International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22.<\/li>\n<li>Chen PT, Chiang CJ, <strong>Chen YT<\/strong>, Lin HC, Liu CH, Chao YP* and Shaw JF* (2012) Chromosome engineering <em>Escherichia coli <\/em>host for the efficient production of <em>Picrophilus torridus<\/em> trehalose synthase. International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Best Poster Award)<\/li>\n<li>Cheng CY, Shaw JF*, <strong>Chen YT<\/strong>* (2012) Cloning and characterization of glutaredoxin from <em>Chlorella sorokiniana <\/em> International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Excellent Poster Award)<\/li>\n<li>Zeng WW, Wang WN, Shaw JF*, and <strong>Chen YT<\/strong>* (2012) Improvement of the antioxidant activity of <em>Antrodia Cinnamomea <\/em>by medium modification and adding methanolic extract of <em>Cinnamomum kanehirae <\/em> International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Excellent Poster Award)<\/li>\n<li>Lee JH, <strong>Chen YT<\/strong>*, Chuang HH, Chiu JM (2012) Cloning and characterization cinnamyl alcohol dehydrogenase from <em>Chlorella sorokiniana<\/em> International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Excellent Poster Award)<\/li>\n<li>Hsu-Han Chuang, Yu-Ting Chen* and Jei-Fu Shaw (2013) (Invited Lecture) Study the gene functions of rice lipases\/esterases by using functional proteomics approaches. The 9th International Symposium on Agricultural Biocatalysis and Biotechnology. Pie\u0161\u0165any, Slovak Republic, Oct 13 \u2013 16, 2013.<\/li>\n<li>Fang-Yu Hsu, Cheng Huan Liu, Yu Ting Chen, Po Ting Chen, Chin-Shuh Chen, Jei Fu Shaw*, Gene analysis and Biochemical Characterization of a Novel Recombinant Lipase rGtLIP1 from<em> Geobacillus thermodenitrificans<\/em> The 10th International Symposium on Agricultural Biocatalysis and Biotechnology. Kaohsiung, Taiwan, Oct 28-31, 2014. (Best Young Investigator Conference paper Award)<\/li>\n<li>Hsien-Yu Chao, Yu-Ting Chen*, Rice GDSL Lipase may Promote Grain Yield and Salt Resistance. The 10th International Symposium on Agricultural Biocatalysis and Biotechnology. Kaohsiung, Taiwan, Oct 28-31, 2014. (Best Pastor Award)<\/li>\n<li>Chih-Ming Chiu, Hsien-Yu Chao, Yu-Ting Chen*, Physiological Function of GDSL-lipase in Rice (<em>Oryza sativa<\/em>). The 10th International Symposium on Agricultural Biocatalysis and Biotechnology. Kaohsiung, Taiwan, Oct 28-31, 2014.<\/li>\n<li>Yi-Hao Huang, Wen-Wen Zeng, Wun-Nai Wang, Yu-Ting Chen*, Improvement of the Antioxidant Activity of Antrodia cinnamomea by Medium Modification and Adding Methanolic Extract of Cinnamomum kanehirae Leaf. The 10th International Symposium on Agricultural Biocatalysis and Biotechnology. Kaohsiung, Taiwan, Oct 28-31, 2014.<\/li>\n<li>Yi-Ting Kuo, Jia-Hui Lee, Yu-Ting Chen*, Beta-Carotene Ketolase of Chlorella. sp. DT Cloning and Overexpression for Astaxanthin Production in Transgenic Plant. The 10th International Symposium on Agricultural Biocatalysis and Biotechnology. Kaohsiung, Taiwan, Oct 28-31, 2014. (Best Pastor Award)<\/li>\n<li>Jyung-Hurng Liu, Hsu-Han Chuang, Ting-Wen Chen, Jei-Fu Shaw, and Yu-Ting Chen* (invited speaker and chair) Structural and functional relation analysis of glutaredoxin from Chlorella sorokiniana T89. The 12th International Symposium on Agricultural Biocatalysis and Biotechnology. Hong Kong, Oct 17-19, 2016.<\/li>\n<li>Jyung-Hurng Liu, Hsu-Han Chuang, Ting-Wen Chen, Jei-Fu Shaw, and Yu-Ting Chen* (Invited speaker) Catalytic related amino acid of glutaredoxin from Chlorella sorokiniana T89. 12th Cross-Strait International Conference on Symposium on Plant Molecular Biology and Biotechnology. Kaohsiung, Taiwan, Nov 2-4, 2016.<\/li>\n<li>Cheng Huan Liu; Po-Ting Chen; Fang-Yu Hsu; Yu-Ting Chen; Chin-Shuh Chen, Jei-Fu Shaw, Thermal stable esterase (rGtEst1) of <em>Geobacillus thermodnitrificans<\/em> 12th Cross-Strait International Conference on Symposium on Plant Molecular Biology and Biotechnology. Kaohsiung, Taiwan, Nov 2-4, 2016.<\/li>\n<li>Wen-Wen Zeng, Tsan-Chi Chen, Sheng-Yang Wang, Cheng-Huan Liu, Yu-Ting Chen, Identification of an anti-proliferative 2,4-dimethoxy-6-methylbenzene- 1,3-diol from<em> Antrodia cinnamomea<\/em>. 12th Cross-Strait International Conference on Symposium on Plant Molecular Biology and Biotechnology. Kaohsiung, Taiwan, Nov 2-4, 20164.<\/li>\n<li>Wen-Wen Zeng, Sheng-Yang Wang, Cheng-Huan Liu, Yu-Ting Chen, Identification of a dual-function phenolic compound with anti-oxidant and anti-proliferative activities in <em>Antrodia cinnamome<\/em>. 2016\u4e2d\u8349\u85e5\u5728\u6297\u8001\u5316\u690d\u7269\u65b0\u85e5\u4e4b\u61c9\u7528\u8da8\u52e2\u7814\u8a0e\u6703. Tainan, Taiwan, Nov 3, 2016.<\/li>\n<li>Jyung-Hurng Liu*, Chih-Yuan Nien, Chu-Wei Chang, Chun-Siou Hong, Shu-Wei Chang, Yu-Ting Chen and Jei-Fu Shaw (2017, Oct). Contribution of surface residues on the thermostability of the trehalose synthase from Picrophilus torridus. 13th International Symposium on Agricultural Biocatalysis and Biotechnology, Taichung, Taiwan. MOST 106-2313-B-005-035-MY2.<\/li>\n<li>Ting-Wei Lin, Yi-Ting Kou, Cheng-Huan Liu, Wei-Ting Lin, Yu-Ting Chen* (2018, Oct). Build up the highest astaxanthin production platform by using optima cultural condition analysis of Chlorella. sp. DT and the transgenic approach. 14th International Symposium on Agricultural Biocatalysis and Biotechnology, Kuala Lumpur, Malaysia. MOST 106-2313-B-005-035-MY2. \u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005.<\/li>\n<li>Cheng-Huan Liu, Yu-Ting Chen, Chin-Shuh Chen, Jei-Fu Shaw (2017, Oct). Lipase cloned from Staphylococcus epidermidis: crystallization and X-ray crystallographic analysis. 13th International Symposium on Agricultural Biocatalysis and Biotechnology, Taichung, Taiwan. MOST 106-2313-B-005-035-MY2.<\/li>\n<li>Ting-Wei Lin, Yi-Ting Kou, Cheng-Huan Liu, Wei-Ting Lin, Yu-Ting Chen* (2018, Oct). Build up the highest astaxanthin production platform by using optima cultural condition analysis of Chlorella. sp. DT and the transgenic approach. 14th International Symposium on Agricultural Biocatalysis and Biotechnology, Kuala Lumpur, Malaysia. MOST 106-2313-B-005-035-MY2. \u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005.<\/li>\n<li>Li JR, Liu CC, Sun CH, Chen YT* (2019, Mar). Plant stress RNA-seq Nexus: a stress-specific transcriptome database in plant cells. Japan-Taiwan Plant Biology. 2019, Nagoya, Japan. MOST 106-2313-B-005-035-MY2. \u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005<\/li>\n<li>Lin TW, Kou YT, Liu CH, Lin WT, Chen YT* (2019, May). Optimize the astaxanthin production platform by using optima cultural condition analysis of Chlorella. sp. DT and the transgenic approach.. 2019 AOCS Annual Meeting, St. Louis, USA. MOST 106-2313-B-005-035-MY2. \u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005.<\/li>\n<li>Li JR, Liu CC, Sun CH, Chen YT* (2019, Sep). A large-scale RNA-Seq database of plant stress-specific transcriptome: Plant Stress RNA-seq Nexus. 15<sup>th<\/sup> International Symposium on Agricultural Biocatalysis and Biotechnology, Hiroshima, Japan.\u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005.<\/li>\n<li>Liu CH, Wu YH, <strong><u>ChenYT*<\/u><\/strong> and Jei-Fu Shaw JF* (2020, Oct). Crystallographic analysis and characterization of the Staphylococcus epidermidis lipase. \u570b\u5bb6\u751f\u6280\u5927\u85cd\u5716\u7814\u8a0e\u6703. MOST 109-2311-B-005-019. \u672c\u4eba\u70ba\u901a\u8a0a\u4f5c\u8005<\/li>\n<li>\u5f90\u4f69\u6148\u3001<strong>\u9673\u7389\u5a77<\/strong>\u3001\u4f59\u8070\u5b89*(2020, Oct)\u3002\u53f0\u7063\u6749\u7d44\u7e54\u57f9\u990a\u82d7\u4e4b\u5efa\u7acb\u8207\u85c9\u7531\u81bf\u687f\u83ccRi\u57fa\u56e0\u8f49\u6b96\u4e4b\u63a2\u8a0e\u3002\u570b\u5bb6\u751f\u6280\u5927\u85cd\u5716\u7814\u8a0e\u6703\u3002<\/li>\n<li>\u9ec3\u632f\u51f1\u3001\u9673\u7389\u5a77\u3001\u4f59\u8070\u5b89*(2020, Oct)\u6fb3\u6d32\u8336\u6a39\u7d44\u7e54\u57f9\u990a\u5efa\u7acb\u8207\u4e0d\u540c\u6d88\u6bd2\u689d\u4ef6\u7684\u63a2\u8a0e\u3002\u570b\u5bb6\u751f\u6280\u5927\u85cd\u5716\u7814\u8a0e\u6703\u3002<\/li>\n<li>Zeng WW, Chen TC, Liu CH, Wang SY, Shaw JF, and <strong><u>Chen YT*<\/u><\/strong> (2021, Dec.) (invited speaker) Identification of a dual-function phenolic compound with anti-oxidant and anti-proliferative activities in <em>Antrodia cinnamomea<\/em>. \u8fb2\u696d\u751f\u6280\u806f\u5408\u7814\u8a0e\u6703\u3002<\/li>\n<li>Hsu PT, Hsu YC, Tu MH, <strong><u>Chen YT<\/u><\/strong> and Yu TA* (2021, Dec.) The establishment of cantaloupe (<em>Cucumis melo<\/em>) production under LED plant factory.\u8fb2\u696d\u751f\u6280\u806f\u5408\u7814\u8a0e\u6703\u3002<\/li>\n<li>Chen HE, Liu CH, <strong><u>Chen YT<\/u><\/strong>, Huang CC and Liu JH* (2021, Dec.) Structure determination and bioinformatic analysis of dehalogenase from <em>Burkholderia cenocepacia <\/em> \u8fb2\u696d\u751f\u6280\u806f\u5408\u7814\u8a0e\u6703\u3002<\/li>\n<li>Wong MW, Wu TY, Lin YJ, <strong><u>Chen YT<\/u><\/strong>, Yu TA* (2021, Dec.) Establishment of Productive System of Bulgarian Rose and Honey Rose under Plant Factory. \u8fb2\u696d\u751f\u6280\u806f\u5408\u7814\u8a0e\u6703\u3002<\/li>\n<li>Li JA, Chen<strong><u> YT<\/u><\/strong>, Lu CH, Yu TA* (2022, Nov.) Establish the production system of ice plant (<em>Mesembryanthemum crystallinum<\/em>) in the plant factory. 16<sup>th<\/sup> International Symposium on Biocatalysis and Agricultural Biotechnology (Taichung, Taiwan)<\/li>\n<li>Chen GW, Chen YT, Yang TH, Yu TA* (2022, Nov.) Effects of different culture conditions on cutting of <em>Carica papaya<\/em> Single Shoot from Culture tissue. 16<sup>th<\/sup> International Symposium on Biocatalysis and Agricultural Biotechnology (Taichung, Taiwan)<\/li>\n<li><strong>Chen YT*<\/strong> (2022, Nov.) (invited speaker) An Antioxidant and Anti-Proliferative Metabolite, DMMB, of <em>Antrodia cinnamomea<\/em>. International Symposium on Taiwan Medical Mushrooms: Antrodia cinnamomea (Taipei, Taiwan)<\/li>\n<li>Ho CA, Huang WE,<strong> Chen YT<\/strong>, Yu TA* (2023 Nov) Growth Evaluation of Different Strawberry Cultivars in Plant Factory. 17<sup>th<\/sup> International Symposium on Biocatalysis and Agricultural Biotechnology (Taichung, Taiwan)<\/li>\n<li>Fang WJ, Chen GJ, <strong>Chen YT<\/strong>, Yu TA* (2023 Nov) Comparing the Propagation Using Shoot Tip and Node Culture of <em>Vanilla Planifolia <\/em>Tissue Culture <em>In Vitro<\/em>. 17<sup>th<\/sup> International Symposium on Biocatalysis and Agricultural Biotechnology (Taichung, Taiwan)<\/li>\n<li>Li JA, Wong MW, <strong>Chen YT<\/strong>, Yu TA* (2023 Nov) Shoot Tip Culture of Black Ginger (<em>Kaempferia parviflora<\/em>). 17<sup>th<\/sup> International Symposium on Biocatalysis and Agricultural Biotechnology (Taichung, Taiwan)<\/li>\n<li>Liu JH, and <strong><u>Chen YT<\/u><\/strong>* (2024 Oct, invited speaker) Screening and characterization of powdery mildew resistance genes in melon (<em>Cucumis melo<\/em>). 18<sup>th<\/sup> International Symposium on Biocatalysis and Agricultural Biotechnology. (Bratislava, Slovak Republic) October 16\u201318, 2024<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5c08\u66f8<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li><strong>\u9673\u7389\u5a77<\/strong>\u3001\u9673\u69ae\u82b3\u3001\u9ec3\u9e97\u6625\u3001\u856d\u4ecb\u592b (2004) \u690d\u7269\u57fa\u56e0\u8f49\u6b96\u5728\u690d\u7269\u4fdd\u9bae\u5132\u904b\u4e0a\u4e4b\u61c9\u7528\uff0c\u6559\u80b2\u90e8\u690d\u7269\u751f\u7269\u6280\u8853\u6559\u5b78\u8cc7\u6e90\u4e2d\u5fc3\u4e3b\u7de8\u2014\u690d\u7269\u57fa\u56e0\u8f49\u6b96\u4e4b\u539f\u7406\u8207\u61c9\u7528\uff0c2004\uff0cp243-254\u3002<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5c08\u5229<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>Shaw, J.F., <strong>T. Chen<\/strong>, L.H. Hus. Novel chitinase and use thereof. U.S.A patent US7670820, Jan 14, 2008-Jan 17, 2028 (March 2, 2010)<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<ul class=\"team-manager-free-items-style2-social_media_team-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-teamprofiles-1739\">\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-title-1739\">\r\n\t\t\t\t\t\t\t\t<a href=\"\" data-featherlight=\"#fl12140390717\">\r\n\t\t\t\t\t\t\t\t\t\u9673\u7389\u5a77\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-post-1739\">\r\n\t\t\t\t\t\t\t\t\u526f\u6559\u6388\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<p style=\"display:block\" class=\"team-manager-free-items-style2-team-description-1739\">\r\n\t\t\t\t\t\t\t\t\u7814\u7a76\u65b9\u5411:\u5206\u5b50\u751f\u7269\uff0c\u690d\u7269\u57fa\u56e0\u8f49\u6b96\uff0c\u690d\u7269\u529f\u80fd\u6027\u57fa\u56e0\u9ad4\uff0c\u751f\u7269\u80fd\u6e90\t\t\t\t\t\t\t<\/p>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t\t<div class=\"teamshowcasefree-col-lg-3 teamshowcasefree-col-md-2 teamshowcasefree-col-sm-2 teamshowcasefree-col-xs-1\">\r\n\t\t\t\t\t<div class=\"team-manager-free-items-style2-1739\">\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-pic-1739\">\r\n\t\t\t\t\t\t\t<a href=\"#\" data-featherlight=\"#fl1209956372\">\r\n\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_LiuJyungHurng.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t<div class=\"lightbox\" id=\"fl1209956372\">\r\n\t\t\t\t\t\t\t\t\t<div class=\"team_popup_container-1739\">\r\n\t\t\t\t\t\t\t\t\t\t<h2>\u5289\u4fca\u5b8f<\/h2>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area_img-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_LiuJyungHurng.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_contact_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\"><a href=\"mailto:jhliu@nchu.edu.tw\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\tjhliu@nchu.edu.tw<\/a><\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">(04)22840338 #7181(\u8fa6\u516c\u5ba4) #7131(\u5be6\u9a57\u5ba4)<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">\u9632\u75ab\u6aa2\u75ab\u5927\u6a137\u6a13 718 \u5ba4<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<ul class=\"team-manager-popup-items-social-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_right_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<p><a href=\"https:\/\/orcid.org\/0000-0002-7173-0372\"><img loading=\"lazy\" class=\"wp-image-2595 alignright\" src=\"http:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png\" alt=\"\" width=\"79\" height=\"79\" srcset=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png 150w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-24x24.png 24w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-36x36.png 36w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-48x48.png 48w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948.png 190w\" sizes=\"(max-width: 79px) 100vw, 79px\" \/><\/a>\u7814\u7a76\u5ba4:<a href=\"https:\/\/bertie.igb.nchu.edu.tw\/jhliu\/index.html\">\u7d50\u69cb\u751f\u7269\u8cc7\u8a0a\u6838\u5fc3\u5be6\u9a57\u5ba4<\/a><\/p>\n<h4>\u69ae\u8b7d<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"14%\">\u6642\u9593<\/th>\n<th width=\"86%\">\u5167\u5bb9<\/th>\n<\/tr>\n<tr>\n<td>2006\/07<\/td>\n<td>&#8220;Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin: crystal structure of the cardiotoxin\/sulfatide complex.&#8221;<br \/>\n\u4e2d\u592e\u7814\u7a76\u9662\u5206\u5b50\u751f\u7269\u7814\u7a76\u6240 \u5b78\u751f\/\u52a9\u7406\/\u535a\u58eb\u5f8c\u7533\u8acb\u51fa\u5e2d\u570b\u969b\u5b78\u8853\u6703\u8b70\u734e\u52a9<\/td>\n<\/tr>\n<tr>\n<td>2004\/10<\/td>\n<td>&#8220;Crystal structure of PriB, a primosomal DNA replication protein of Escherichia coli.&#8221;<br \/>\n\u570b\u5bb6\u540c\u6b65\u8f3b\u5c04\u7814\u7a76\u4e2d\u5fc3\u7b2c\u5341\u5c46\u7528\u6236\u5e74\u6703\u66a8\u7814\u8a0e\u6703 \u5b78\u751f\u53e3\u982d\u5831\u544a\u6bd4\u8cfd\u7b2c\u4e8c\u540d\u8207\u58c1\u5831\u6bd4\u8cfd\u4f73\u4f5c<\/td>\n<\/tr>\n<tr>\n<td>2004\/05<\/td>\n<td>&#8220;Crystal structure of PriB, a primosomal DNA replication protein of Escherichia coli.&#8221;<br \/>\n\u7b2c\u4e5d\u5c46\u751f\u7269\u7269\u7406\u65b0\u77e5\u7814\u8a0e\u6703\u9752\u5e74\u5b78\u5b50\u58c1\u5831\u8ad6\u6587\u734e\u7b2c\u4e8c\u540d<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u7c21\u8981\u7d93\u6b77<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"20%\">\u8077\u7a31<\/th>\n<th width=\"54%\">\u670d\u52d9\u55ae\u4f4d<\/th>\n<th width=\"26%\">\u8d77\u8a16\u5e74\u6708<\/th>\n<\/tr>\n<tr>\n<td>\u526f\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2020\/08 \u2013 \u8fc4\u4eca<\/td>\n<\/tr>\n<tr>\n<td>\u5408\u8058\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78\u751f\u7269\u6280\u8853\u5b78\u7814\u7a76\u6240<\/td>\n<td>2008\/08 &#8211; \u8fc4\u4eca<\/td>\n<\/tr>\n<tr>\n<td>\u5c08\u4efb\u52a9\u7406\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2009\/02 &#8211; 2020\/07<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u53f0\u7063\u751f\u7269\u7269\u7406\u5b78\u6703<\/td>\n<td>2007\/05 &#8211;<\/td>\n<\/tr>\n<tr>\n<td>\u517c\u4efb\u52a9\u7406\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u6280\u8853\u5b78\u7814\u7a76\u6240<\/td>\n<td>2007\/02 &#8211;<\/td>\n<\/tr>\n<tr>\n<td>\u5408\u8058\u52a9\u7406\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u751f\u547d\u79d1\u5b78\u7cfb<\/td>\n<td>2007\/02 -\u8fc4\u4eca<\/td>\n<\/tr>\n<tr>\n<td>\u5c08\u4efb\u52a9\u7406\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u751f\u7269\u79d1\u6280\u767c\u5c55\u4e2d\u5fc3<\/td>\n<td>2008\/08 -\u8fc4\u4eca<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb\u5f8c\u7814\u7a76\u54e1<\/td>\n<td>\u4e2d\u592e\u7814\u7a76\u9662 \u5206\u5b50\u751f\u7269\u7814\u7a76\u6240<\/td>\n<td>2006\/01 &#8211; 2007\/01<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb<\/td>\n<td>\u570b\u9632\u91ab\u5b78\u9662\u3001\u4e2d\u592e\u7814\u7a76\u9662\u3001\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u5408\u8fa6\u751f\u547d\u79d1\u5b78\u7814\u7a76\u6240<\/td>\n<td>2001\/08 &#8211; 2005\/12<\/td>\n<\/tr>\n<tr>\n<td>\u78a9\u58eb<\/td>\n<td>\u570b\u7acb\u967d\u660e\u5927\u5b78 \u907a\u50b3\u5b78\u7814\u7a76\u6240<\/td>\n<td>1995\/09 &#8211; 1997\/06<\/td>\n<\/tr>\n<tr>\n<td>\u5b78\u58eb<\/td>\n<td>\u53f0\u5317\u91ab\u5b78\u9662 \u85e5\u5b78\u7cfb<\/td>\n<td>1991\/09 &#8211; 1995\/06<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u5c08\u696d\u8a13\u7df4<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5167\u5bb9<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>\u7f8e\u570b\u7d50\u6676\u5b78\u6703\u6691\u671f\u8a13\u7df4\u8ab2\u7a0b\u300cSummer course in crystallography\u300d\u86cb\u767d\u8cea\u7d50\u69cb\u8207\u529f\u80fd(Structure and function of proteins) \u7f8e\u570b\u55ac\u6cbb\u4e9e\u5927\u5b78 (2001\/06)<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u5b78\u8853\u6f14\u8b1b<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5167\u5bb9<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>&#8220;Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin: crystal structure of the cardiotoxin\/sulfatide complex.&#8221;\u7f8e\u570b\u7d50\u6676\u5b78\u6703 2006 \u5e74\u5e74\u6703\u300c\u74b0\u592a\u5e73\u6d0b\u5730\u5340X\u5149\u8207\u4e2d\u5b50\u8a2d\u65bd\u7684\u79d1\u5b78\u7814\u7a76\u300d\u8b70\u7a0b (2006\/07)<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u5b78\u8207\u7814\u7a76<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u958b\u8a2d\u8ab2\u7a0b \u00a0\u00a0\u00a0\u00a0[\u6559\u6750\u4e0b\u8f09]<\/th>\n<\/tr>\n<tr>\n<td>\n<ul class=\"Exp\">\n<li>[\u5927\u5b78\u90e8] \u751f\u7269\u5316\u5b78<\/li>\n<li>[\u5927\u5b78\u90e8] \u751f\u7269\u6280\u8853<\/li>\n<li>[\u7814\u7a76\u6240] \u7814\u7a76\u6240<\/li>\n<li>[\u7814\u7a76\u6240] \u5c08\u984c\u8a0e\u8ad6<\/li>\n<li>[\u7814\u7a76\u6240] \u751f\u7269\u5316\u5b78\u7279\u8ad6<\/li>\n<li>[\u7814\u7a76\u6240] \u61c9\u7528\u57fa\u56e0\u9ad4\u5b78\u53ca\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2<\/li>\n<li>[\u7814\u7a76\u6240] \u86cb\u767d\u8cea\u5de5\u7a0b\u5b78<\/li>\n<li>[\u7814\u7a76\u6240] \u86cb\u767d\u8cea\u5206\u5b50\u6a21\u64ec\u53ca\u7406\u8ad6\u85e5\u7269\u8a2d\u8a08<\/li>\n<li>[\u751f\u6280\u535a\u58eb\u73ed] \u751f\u7269\u5316\u5b78\u7279\u8ad6<\/li>\n<li>[\u751f\u6280\u535a\u58eb\u73ed] \u6280\u8853\u7279\u8ad6<\/li>\n<li>[\u901a\u8b58\u6559\u80b2\u8b1b\u5ea7] \u751f\u547d\u79d1\u5b78\u8207\u4eba\u751f<\/li>\n<li>[\u6691\u671f\u6838\u5fc3\u8ab2\u7a0b\u5b78\u5206\u73ed] \u751f\u7269\u8cc7\u8a0a\u5b78\u5728\u751f\u547d\u79d1\u5b78\u4e0a\u4e4b\u61c9\u7528\u66a8\u5be6\u7fd2<\/li>\n<li>[\u6691\u671f\u6838\u5fc3\u8ab2\u7a0b\u5b78\u5206\u73ed] \u529f\u80fd\u86cb\u767d\u8cea\u9ad4\u5b78\u66a8\u5be6\u7fd2<\/li>\n<li>[\u6691\u671f\u6838\u5fc3\u8ab2\u7a0b\u5b78\u5206\u73ed] \u57fa\u56e0\u9ad4\u5b78<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u7a76\u5c08\u9577<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>\u86cb\u767d\u8cea\u7d50\u69cb\u89e3\u6790<\/li>\n<li>\u7d50\u69cb\u751f\u7269\u8cc7\u8a0a\u5b78<\/li>\n<li>\u751f\u7269\u5206\u5b50X\u5149\u6676\u8b5c\u5b78<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u7814\u7a76\u4e3b\u984c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5be6\u9a57\u5ba4\u7814\u7a76\u65b9\u5411\u00a0\u00a0\u00a0\u00a0[\u8a73\u7d30\u5167\u5bb9]<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\n<p class=\"pHead\">\u7814\u7a76\u4e3b\u984c:<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\">\u5de5\u696d\u9175\u7d20\u7684\u86cb\u767d\u8cea\u7d50\u69cb\u6539\u826f \u7d30\u83cc\u6297\u85e5\u6027\u9175\u7d20\u7684\u7d50\u69cb\u89e3\u6790\u8207\u65b0\u85e5\u958b\u767c\u3001\u771f\u6838\u7d30\u80de\u5167\u6838\u7cd6\u9ad4\/\u8a0a\u865f\u8fa8\u8b58\u7c92\u5b50\/\u86cb\u767d\u8cea\u8f49\u4f4d\u9ad4\u9593\u7684\u4ea4\u4e92\u4f5c\u7528\u3001\u9175\u6bcd\u83cc\u67d3\u8272\u8cea\u91cd\u5851\u8907\u5408\u9ad4 RSC\u3001\u679c\u8805 JAK\/STAT \u8a0a\u606f\u50b3\u905e\u9014\u5f91\u3001\u93c8\u9ef4\u83cc\u67d3\u8272\u9ad4\u672b\u7aef\u86cb\u767d<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\">\u672c\u5be6\u9a57\u5ba4\u76ee\u524d\u7814\u7a76\u4ee5\u4e0b\u86cb\u767d\u8cea\u7684\u7d50\u69cb\uff0c\u4e26\u63a2\u8a0e\u5176\u5728\u751f\u7269\u9ad4\u5167\u7684\u529f\u80fd\uff1a<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\"><span class=\"Span-Title\">I. \u771f\u6838\u7d30\u80de\u5167\u6838\u7cd6\u9ad4\/\u8a0a\u865f\u8fa8\u8b58\u7c92\u5b50\/\u86cb\u767d\u8cea\u8f49\u4f4d\u9ad4\u9593\u7684\u4ea4\u4e92\u4f5c\u7528<\/span><\/p>\n<p>\u771f\u6838\u751f\u7269\u6838\u7cd6\u9ad4 (Ribosome) \u86cb\u767d L23a \u8207 L35 (\u5728\u539f\u6838\u751f\u7269\u5167\u7684\u540c\u6e90\u86cb\u767d\u70ba L23 \u8207 L29 ) \u5728\u806f\u7e6b\u86cb\u767d\u8cea\u5408\u6210\u3001\u647a\u758a (Folding) \u8207\u5f8c\u7e8c\u904b\u9001 (Sorting) \u4e0a\u626e\u6f14\u91cd\u5927\u7684\u89d2\u8272\u3002\u56e0\u70ba L23a \u8207 L35 \u525b\u597d\u4f4d\u5728\u6838\u7cd6\u9ad4\u8207\u76e3\u8b77\u86cb\u767d (Chaperones)\u3001\u8a0a\u865f\u8fa8\u8b58\u7c92\u5b50 (Signal recognition particle, SRP) \u4ee5\u53ca\u86cb\u767d\u8cea\u8f49\u4f4d\u9ad4 (Translocon) Sec61 \u76f8\u63a5\u89f8\u7684\u95dc\u9375\u5730\u57df\u3002\u96d6\u7136\u8fd1\u5e7e\u5e74\u4f86\u9678\u7e8c\u89e3\u51fa\u539f\u6838\u6838\u7cd6\u86cb\u767d L23 \u8207 L29 \u7684\u6676\u9ad4\u7d50\u69cb\uff0c\u7531\u65bc\u771f\u6838\u6838\u7cd6\u86cb\u767d L23a \u8207 L35 \u4e0d\u8ad6\u5728\u5c3a\u5bf8\u8207\u5e8f\u5217\u4e0a\u7686\u548c L23 \u8207 L29 \u5dee\u7570\u6975\u5927\uff0c\u5341\u5206\u503c\u5f97\u6df1\u5165\u63a2\u8a0e L23a \u8207 L35 \u5982\u4f55\u5354\u52a9\u6838\u7cd6\u9ad4\u5728\u771f\u6838\u7d30\u80de\u5167\u540c\u6642\u8abf\u63a7\u8f03\u539f\u6838\u7d30\u80de\u66f4\u70ba\u8907\u96dc\u7684\u86cb\u767d\u8cea\u5408\u6210\u3001\u647a\u758a\u8207\u5f8c\u7e8c\u904b\u9001\u3002<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\"><span class=\"Span-Title\">II. \u9175\u6bcd\u83cc\u67d3\u8272\u8cea\u91cd\u5851\u8907\u5408\u9ad4 RSC<\/span><\/p>\n<p>\u5728\u771f\u6838\u7d30\u80de\u5167\uff0c\u57fa\u56e0\u7d44 (Genome) \u901a\u5e38\u88ab\u4fdd\u8b77\u800c\u5305\u88f9\u6210\u67d3\u8272\u8cea (Chromatin)\uff0c\u4ee5\u9632\u6b62\u5916\u4f86\u7684\u50b7\u5bb3\u3002\u4f46\u662f\uff0c\u7576\u7d30\u80de\u8981\u9032\u884c\u53bb\u6c27\u6838\u7cd6\u6838\u9178 (DNA) \u7684\u8f49\u9304 (Transcription)\u3001\u8907\u88fd (Replication)\u3001\u50b7\u5bb3\u4fee\u88dc (Damage repair) \u8207\u91cd\u7d44 (Recombination) \u6642\uff0c\u67d3\u8272\u8cea\u6703\u611f\u53d7\u5230\u7d30\u80de\u7684\u8a0a\u606f\u800c\u6539\u8b8a\u5176\u69cb\u9020\u3002\u67d3\u8272\u8cea\u91cd\u5851\u8907\u5408\u9ad4 (Chromatin remodeling complexes) \u6703\u5229\u7528\u6d88\u8017\u4e09\u78f7\u9178\u817a\u82f7 (ATP) \u4f86\u6539\u8b8a\u6838\u4ec1\u5c0f\u9ad4 (Nucleosomes) \u7684\u7d50\u69cb\u8207\u5206\u4f48\u60c5\u5f62\uff0c\u9032\u800c\u91cd\u5851\u67d3\u8272\u8cea\u7684\u69cb\u9020\u3002\u5728\u9175\u6bcd\u83cc (Saccharomyces cerevisiae) \u7d30\u80de\u5167\u6709\u5169\u7d44\u67d3\u8272\u8cea\u91cd\u5851\u8907\u5408\u9ad4\uff0c\u5206\u5225\u662f SWI\/SNF (SWItch \/ Sucrose NonFermentable) \u8207 RSC (Remodelers of the Structure of Chromatin) \u8907\u5408\u9ad4\u3002\u7136\u800c\u5169\u8005\u4e2d\uff0c\u53ea\u6709 RSC \u8907\u5408\u9ad4\u5c0d\u65bc\u9175\u6bcd\u83cc\u7684\u751f\u5b58\u8207\u7d30\u80de\u9031\u671f\u9032\u884c\u662f\u91cd\u8981\u4e14\u5fc5\u9700\u7684\u3002RSC \u8907\u5408\u9ad4\u5167\u81f3\u5c11\u542b\u6709 16 \u500b\u86cb\u767d\u8cea\uff0c\u5176\u4e2d\u90e8\u5206\u86cb\u767d\u8cea\u6210\u54e1\u4e5f\u540c\u6642\u53c3\u8207 SWI\/SNF \u8907\u5408\u9ad4\u7684\u7d44\u6210\u3002<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\"><span class=\"Span-Title\">III. \u679c\u8805 JAK\/STAT \u8a0a\u606f\u50b3\u905e\u9014\u5f91<\/span><\/p>\n<p>\u7531 Janus activated kinases (JAKs) \u8207 Signal transducers and activators of transcription (STATs) \u7d44\u6210\u7684 JAK\/STAT \u8a0a\u606f\u50b3\u905e\u9014\u5f91\u5f15\u5c0e\u4eba\u9ad4\u5167\u8a31\u591a\u91cd\u8981\u7684\u751f\u7406\u7a0b\u5e8f\uff0c\u5305\u542b\uff1a\u514d\u75ab\u53cd\u61c9\u3001\u8840\u7403\u751f\u6210\u3001\u767c\u708e\u73fe\u8c61\u4ee5\u53ca\u795e\u7d93\u8207\u80da\u80ce\u7684\u767c\u80b2\u3002JAK\/STAT \u8a0a\u606f\u50b3\u905e\u9014\u5f91\u7684\u6301\u7e8c\u6d3b\u5316\u4e5f\u8207\u4eba\u985e\u7684\u591a\u7a2e\u816b\u7624\u7684\u767c\u751f\uff0c\u5c24\u5176\u662f\u9020\u8840\u7cfb\u7d71\u60e1\u6027\u816b\u7624\u6709\u95dc\u3002\u76f8\u8f03\u65bc\u4eba\uff0c\u679c\u8805 (Drosophila melanogaster) \u9ad4\u5167\u6709\u4e00\u5957\u7c21\u55ae\u7684JAK\/STAT \u8a0a\u606f\u50b3\u905e\u9014\u5f91\u3002\u76ee\u524d\u5df2\u77e5\u5176\u4e2d\u4e3b\u8981\u6210\u54e1\u5305\u62ec\uff1a\u4e09\u500b\u914d\u9ad4 (Unpaired\uff1aUpd\u3001Upd2 \u8207 Upd3)\u3001\u4e00\u500b\u7d30\u80de\u819c\u4e0a\u7684\u53d7\u5668 (Domeless, Dome)\u3001\u4e00\u500b JAK (Hopscotch, Hop) \u8207\u4e00\u500b STAT (STAT92E)\u3002\u96d6\u7136\u6210\u54e1\u7c21\u55ae\uff0c\u537b\u53c3\u8207\u4e86\u679c\u8805\u7684\u9ad4\u7bc0\u751f\u6210\u3001\u6027\u5225\u6c7a\u5b9a\u3001\u514d\u75ab\u53cd\u61c9\u3001\u8840\u7403\u751f\u6210\u3001\u773c\u775b\u7d30\u80de\u7684\u589e\u751f\u53ca\u5206\u5316\u3001\u4ee5\u53ca\u4e2d\u6a1e\u795e\u7d93\u3001\u5f8c\u8178\u8207\u6c23\u7ba1\u7684\u767c\u80b2\u3002<\/p>\n<p>&nbsp;<\/p>\n<p class=\"pHead\"><span class=\"Span-Title\">IV. \u93c8\u9ef4\u83cc\u67d3\u8272\u9ad4\u672b\u7aef\u86cb\u767d<\/span><\/p>\n<p>\u93c8\u9ef4\u83cc (Streptomyces) \u662f\u4e00\u7a2e\u666e\u904d\u5b58\u5728\u65bc\u571f\u58e4\u5167\u7684\u7d72\u72c0\u7d30\u83cc\uff0c\u5c6c\u65bc\u9769\u862d\u6c0f\u967d\u6027\u83cc\u3002\u93c8\u9ef4\u83cc\u53ef\u88fd\u9020\u51fa\u8a31\u591a\u6709\u50f9\u503c\u7684\u91ab\u85e5\u54c1\uff0c\u5176\u4e2d\u4ee5\u7a2e\u985e\u7e41\u591a\u7684\u6297\u751f\u7d20\u6700\u70ba\u4eba\u6240\u6089\u3002\u4e0d\u540c\u65bc\u4e00\u822c\u7d30\u83cc\u5177\u6709\u74b0\u5f62\u7684\u67d3\u8272\u9ad4\uff0c\u93c8\u9ef4\u83cc\u7684\u67d3\u8272\u9ad4\u8207\u8cea\u9ad4\u7684\u69cb\u9020\u70ba\u76f4\u7dda\u5f62\u3002\u93c8\u9ef4\u83cc\u67d3\u8272\u9ad4\u8207\u8cea\u9ad4\u7684\u7aef\u7c92 (Telomeres) \u5747\u5e36\u6709\u672b\u7aef\u86cb\u767d (Terminal proteins)\uff0c\u5b83\u5011\u4ee5\u5171\u50f9\u9375\u7d50\u5408\u4e0a\u53bb\u6c27\u6838\u7cd6\u6838\u9178 (DNA) \u7684 5&#8242; \u7aef\u3002\u9664\u4e86\u4fdd\u8b77\u67d3\u8272\u9ad4\u8207\u8cea\u9ad4\u7684\u7aef\u7c92\u69cb\u9020\uff0c\u76ee\u524d\u8a8d\u70ba\u7576\u93c8\u9ef4\u83cc\u67d3\u8272\u9ad4\u5229\u7528\u672c\u8eab\u7684\u8907\u88fd\u8d77\u59cb\u9ede (The chromosomal origin of replication, OriC) \u9032\u884c\u96d9\u5411\u8907\u88fd\u5f8c\uff0c\u672b\u7aef\u86cb\u767d\u9084\u64d4\u7576\u5f15\u5b50 (Primer) \u4f86\u88dc\u9f4a\u5ef6\u9072\u80a1 (The lagging strand) \u4e0a\u7684\u7aef\u9ede\u8907\u88fd\u554f\u984c (The end replication problem)\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u8457\u4f5c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u671f\u520a\u8ad6\u6587 (*Corresponding author)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li>Salem, G.M., Galula, J.U., Wu, SR.<strong><u>Liu, J.-H<\/u><\/strong> ,<i>et al.<\/i>\u00a0Antibodies from dengue patients with prior exposure to Japanese encephalitis virus are broadly neutralizing against Zika virus.\u00a0<i>Commun Biol<\/i>(2024)<\/li>\n<li>Tseng YW, Yang TJ, Hsu YL, <strong><u>Liu, J.-H.*<\/u><\/strong>, Tseng YC, Hsu TW, Lu Y, Pan SH, Cheng TR, Fang JM. Dual-targeting compounds possessing enhanced anticancer activity via microtubule disruption and histone deacetylase inhibition. Eur J Med Chem(2024)<\/li>\n<li>Fang, Y.-T., Lai, W.-S., <strong><u>Liu, J.-H.*<\/u><\/strong>, Liu, Y.-C.*: Enhanced cecropin B2 production via chitin-binding domain and intein self-cleavage system. Biotechnology And Applied Biochemistry(2018)<\/li>\n<li>Shen, W.-F., Galula, J.U., <strong><u>Liu, J.-H.<\/u><\/strong>, Liao, M.-Y., Huang, C.-H., Wang, Y.-C., Wu, H.-C., Liang, J.-J., Lin, Y.-L., Whitney, M.-T., Chang, G.-J., Chen, S.-R., Wu, S.-R., Chao, D.-Y.: Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody. Elife(2018)<\/li>\n<li>Chiu, H.-C., Huang, W.-R., Liao, T.-L., Chi, P.-I., Nielsen, B.L., <strong><u>Liu, J.-H.<\/u><\/strong>, Liu, H.-J.: Mechanistic insights into avian reovirus p17-modulated suppression of cell cycle CDK-cyclin complexes and enhancement of p53 and cyclin H interaction. Journal Of Biological Chemistry(2018)<\/li>\n<li>Lee, C.-Y., Lin, C.-C., Liu, Y.-L., Liu, G.-Y.*, <strong><u>Liu, J.-H.*<\/u><\/strong>, Hung, H.-C.*: Molecular interplay between the dimer interface and the substrate-binding site of human peptidylarginine deiminase 4. Scientific Report(2017)<\/li>\n<li>Li, C., Bai, X., Meng, R., Shaozhou, W., Zhang, Q., Hua, R., <strong><u>Liu, J.-H.<\/u><\/strong>, Liu, M., Zhang, Y.*: Identification of a new broadly cross-reactive epitope within domain III of the duck Tembusu virus E protein. Scientific Reports(2016)<\/li>\n<li>Li, C., Liu, J., Shaozhou, W., Bai, X., Zhang, Q., Hua, R., <strong><u>Liu, J.-H.*<\/u><\/strong>, Liu, M.*, Zhang, Y.*: Epitope identification and application for diagnosis of duck Tembusu virus infections in ducks. VIRUSES-BASEL(2016)<\/li>\n<li>Kuo, T.-C., Li, L.-W., Pan, S.-H.*, Fang, J.-M.*, <strong><u>Liu, J.-H.<\/u><\/strong>, Cheng, T.-J., Wang, C.-J., Hung, P.-F., Chen, H.-Y., Hong, T.-M., Hsu, Y.-L., Wong, C.-H., Yang, P.-C.: Purine-type compounds induce microtubule fragmentation and lung cancer cell death through interaction with katanin. Journal of Medicinal Chemistry(2016)<\/li>\n<li>Chen, J.-C., <strong><u>Liu, J.-H.<\/u><\/strong>, Hsu, D.-W., Shu, J.-C., Chen C.-Y., Chen, C.-C.*: Methylatable signaling\u00a0helix coordinated inhibitory receiver domain in sensor kinase modulates environmental\u00a0stress response in Bacillus cereus. PLoS One(2015)<\/li>\n<li>Hsieh, J.-Y., Li, S.-Y., Tsai, W.-C., <strong><u>Liu, J.-H.<\/u><\/strong>, Lin, C.-L., Liu, G.-Y.*, Hung, H.-C.*: A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence. Oncotarget(2015)<\/li>\n<li>Lin, H.-Y., <strong><u>Liu, J.-H.<\/u><\/strong>, Cheng, K.-L., Lin, J.-Y., Liu, N.-R., Meng, M.-H.*: A novel binding of GTP stabilizes the structure and modulates the activities of human phosphoglucose isomerase\/autocrine motility factor. Biochemistry and Biophysics Reports(2015)<\/li>\n<li>Hsieh, J.-Y., Li, S.-Y., Chen, M.-C., Yang, P.-C., Chen, H.-Y., Chan, N.-L.*, <strong><u>Liu, J.-H.*<\/u><\/strong>, Hung, H.-C.*: Structural characteristics of the nonallosteric human cytosolic malic enzyme. BIOCHIMICA ET BIOPHYSICA ACTAPROTEINS AND PROTEOMICS(2014)<\/li>\n<li>Hsieh, J.-Y., <strong><u>Liu, J.-H.<\/u><\/strong>, Yang, P.-C., Lin, C.-L., Liu, G.-Y.*, Hung, H.-C.* (2014, Jun). :Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme.PLoS One<\/li>\n<li>1. Chepyshko, H., Lai, C.-P., Huang, L.-M.,\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>, and Shaw, J.-F. (2012, Jul.) Multifunctionality and diversity of GDSL esterase\/lipase gene family in rice (Oryza sativa L. japonica) genome: new insights from bioinformatics analysis. BMC Genomics 13, 309 doi:10.1186\/1471-2164-13-309 <span style=\"text-transform: uppercase;\"><b>(SCI, IF<\/b><\/span>2011=4.073 Times cited :8)<\/li>\n<li>Hsieh, J.-Y.,\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>, Fang, Y.-W., Hung, H.-C. (2009, May.) Dual roles of Lys57 at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme. Biochem. J. 402, 201-9. <span style=\"text-transform: uppercase;\"><b>(SCI, IF<\/b><\/span>2007=4.009 Times cited :0)<\/li>\n<li>Li, T.-N., Chin, K.-H.,\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>, Wang, A H.-J., Chou, S.-H. (2009, May.) XC1028 from Xanthomonas campestris adopts a PilZ domain-like structure without a c-di-GMP switch. Proteins. 75, 282-8. <span style=\"text-transform: uppercase;\"><b>(SCI, IF<\/b><\/span>2007=3.354 Times cited :0)<\/li>\n<li>Chou, C.-C., Chang, C.-W.,\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>, Chen, L.-F., Hsiao, C.-D., Chen, H.-W. (2007, Sep.) Small Ubiquitin-like Modifier Modification Regulates the DNA Binding Activity of Glial Cell Missing Drosophila Homolog a. J. Biol. Chem. 282, 27239-49. <span style=\"text-transform: uppercase;\"><b>(SCI, IF<\/b><\/span>2006=5.808 Times cited :3)<\/li>\n<li>Wang, C.-H.*,\u00a0<span class=\"Span-Author\">Liu, J.-H.*<\/span>, Lee, S.-C., Wu, W.-g., and Hsiao, C.-D. (2006, Jan.) Glycosphingolipid-facilitated membrane insertion and internalization of cobra cardiotoxin: the sulfatide\/cardiotoxin complex structure in a membrane-like environment suggests a lipid-dependent cell-penetrating mechanism for membrane binding polypeptides. J. Biol. Chem. 281, 656-77.(SCI, IF 2006=5.808; Times cited: 15) *These authors contributed equally to this work.<\/li>\n<li><span class=\"Span-Author\">Liu, J.-H.<\/span>, Chang, T.-W., Huang, C.-Y., Chen, S.-U., Wu, H.-N., Chang, M.-C., Hsiao, C.-D. (2004, Nov.) Crystal structure of PriB, a primosomal DNA replication protein of Escherichia coli. J. Biol. Chem. 279, 50465-71. <span style=\"text-transform: uppercase;\"><b>(SCI, IF<\/b><\/span>2006=5.808 Times cited : 5)<\/li>\n<li>Forouhar, F., Huang, W.-N.,\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>, Chien, K.-Y., Wu, W.-g. and Hsiao, C.-D. (2003, Jun.) Structural basis of the membrane-induced cardiotoxin A3 oligomerization. J. Biol. Chem. 278, 21980-8. <span style=\"text-transform: uppercase;\"><b>(SCI, IF<\/b><\/span>2006=5.808 Times cited :21)[PDB]<\/li>\n<li><span class=\"Span-Author\">Liu, J. H.<\/span>, Liao, Y. D., Sun Y. J. (2001, Nov.) Crystallization and preliminary X-ray diffraction analysis of cytotoxic ribonucleases from bullfrog Rana catesbeiana. Acta Crystallogr. D57, 1697-9. <span style=\"text-transform: uppercase;\"><b>(SCI, IF<\/b><\/span>2006=1.687 Times cited :0)<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u7814\u8a0e\u6703\u8ad6\u6587 (*Invited speaker)<\/th>\n<\/tr>\n<tr>\n<td>\n<ol class=\"Exp\">\n<li><strong><u>Liu, J.-H.<\/u><\/strong>, Lee, Y.-P., Yang, J.-Y.: The Crystal Structure of the N-terminally Deleted Type III Effector protein XopAI. The 23th Biophysics Conference.<\/li>\n<li><strong><u>Liu, J.-H.,<\/u><\/strong> Lee, C.-Y., Lin, C.-C., Liu, Y.-L., Liu, G.-Y., Hung, H.-C.: Molecular Dynamics Study on the Interaction between Dimer Interface and Substrate-Binding Site of Human Peptidylarginine Deiminase 4. The 22th Biophysics Conference.<\/li>\n<li><strong><u>Liu, J.-H.:<\/u><\/strong> Replica exchange molecular dynamics method for Trp-cage folding simulation in implicit solvent. The 20th Biophysics Conference.<\/li>\n<li>Peng, L.-W., Chen, Y.-T., and <strong><u>Liu, J.-H.:<\/u><\/strong> Crystallization of Dps protein from <em>Klebsiella oxytoca<\/em> The 20th NSRRC Users&#8217; Meeting.<\/li>\n<li>Lin, C.-W., Hung, H.-C., and <strong><u>Liu, J.-H.:<\/u><\/strong> Crystallization of human cytosolic NADP+-dependent malic enzyme complexed with cofactor and substrates. The 20th NSRRC Users&#8217; Meeting.<\/li>\n<li>Chen, C.-W., Shen, G.-H., Chen, J.-H., and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>(2013, Nov) Virtual screening and experimental verification to identify potential inhibitors of the Erm(41) methyltransferase responsible for bacterial resistance against macrolide antibiotics. \u53f0\u7063\u751f\u7269\u5316\u5b78\u53ca\u5206\u5b50\u751f\u7269\u5b78\u5b78\u67032013\u5e74\u51ac\u4ee4\u71df. (Poster)<\/li>\n<li>Peng, L.-W., Chen, Y.-T. and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>. (2013, Sep) Crystallization of \u03b2-lactamase like protein from Klebsiella oxytoca E718. The 19th NSRRC Users&#8217; Meeting. (Poster)<\/li>\n<li><span class=\"Span-Author\">Liu, J.-H.<\/span>, Chen, C. K.-M., Chang, S.-W., Shaw, J.-F., Wang, A. H.-J., and Liu, J.-H. (2012, Oct.) Preliminary X-ray crystallographic analysis of trehalose synthase from Deinococcus radiodurans. The 18th NSRRC Users&#8217; Meeting. (Poster)<\/li>\n<li>Chen, J.-W., Nien, C.-Y., Chen, C. K.-M., Chang, S.-W., Shaw, J.-F., Wang, A. H.-J., and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>(2012, Oct.) Preliminary X-ray crystallographic analysis of trehalose synthase from Picrophilus torridus. The 18th NSRRC Users&#8217; Meeting. (Poster)<\/li>\n<li>Nien, C.-Y., Cheng, C.-Y.,\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>, Shaw, J.-F., and Chen, Y.-T. (2012, May.) Crystal structure of glutaredoxin from Chlorella sorokiniana T-89. The 17th Biophysics Conference. (Poster)<\/li>\n<li>Hung, S.-J. and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>\u00a0(2012, May.) Design of an accurate predictor for the thermostable protein design in PERT server. The 17th Biophysics Conference. (Poster)<\/li>\n<li>Wu, J.-E., Chiu, S.-W., Yang, J.-Y., and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>\u00a0(2012, Mar.) Crystal structure of XopAI from Xanthomonas axonopodis pv. citri. 2012 International Conference on c-di-GMP and Xanthomonads. (Poster)<\/li>\n<li>Hung, S.-J. and<span class=\"Span-Author\">Liu, J.-H.<\/span>\u00a0(2011, Dec.) PERT: an integrated informatics platform for thermostable protein design. 2011 Taiwan Enzyme Mechanism Conference. (Poster)<\/li>\n<li>Nien, C.-Y., Cheng, C.-Y., Shaw, J.-F., Chen, Y.-T., and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>\u00a0(2011, Oct.) Crystallization and preliminary X-ray crystallographic analysis of Chlorella glutaredoxin. The 17th NSRRC Users&#8217; Meeting. (Poster)<\/li>\n<li>Wu, J.-E., Chiu, S.-W., Yang, J.-Y., and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>\u00a0(2010, Oct.) Crystallization and preliminary X-ray crystallographic analysis of XopAI from Xanthomonas axonopodis pv. citri. The 16th NSRRC Users&#8217; Meeting. (Poster)<\/li>\n<li><span class=\"Span-Author\">Liu, J.-H.<\/span>, Hong, C.-S., Chang, S.-W., and Shaw, J.-F. (2009, Nov.) Investigation of the structural basis for thermostability of trehalose synthase from Picrophilus torridus. The 5th International Symposium on Biocatalysis and Biotechnology. (Poster)<\/li>\n<li>Hsu, Y.-J. and\u00a0<span class=\"Span-Author\">Liu, J.-H.<\/span>\u00a0(2009, Oct.) Effects of trimethylamine-N-oxide (TMAO) on the interactions of lysozyme in crystal. The 15th NSRRC Users&#8217; Meeting. (Poster)<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<ul class=\"team-manager-free-items-style2-social_media_team-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-teamprofiles-1739\">\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-title-1739\">\r\n\t\t\t\t\t\t\t\t<a href=\"\" data-featherlight=\"#fl1209956372\">\r\n\t\t\t\t\t\t\t\t\t\u5289\u4fca\u5b8f\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-post-1739\">\r\n\t\t\t\t\t\t\t\t\u526f\u6559\u6388\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<p style=\"display:block\" class=\"team-manager-free-items-style2-team-description-1739\">\r\n\t\t\t\t\t\t\t\t\u7814\u7a76\u65b9\u5411:\u7d50\u69cb\u751f\u7269\u8cc7\u8a0a\uff0c\u751f\u7269\u5206\u5b50X\u5149\u6676\u8b5c\u5b78\t\t\t\t\t\t\t<\/p>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\r\n\t\t\t\t<div class=\"teamshowcasefree-col-lg-3 teamshowcasefree-col-md-2 teamshowcasefree-col-sm-2 teamshowcasefree-col-xs-1\">\r\n\t\t\t\t\t<div class=\"team-manager-free-items-style2-1739\">\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-pic-1739\">\r\n\t\t\t\t\t\t\t<a href=\"#\" data-featherlight=\"#fl11654893216\">\r\n\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_LiChingHsieh.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t\t<div class=\"lightbox\" id=\"fl11654893216\">\r\n\t\t\t\t\t\t\t\t\t<div class=\"team_popup_container-1739\">\r\n\t\t\t\t\t\t\t\t\t\t<h2>\u8b1d\u7acb\u9752<\/h2>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_left_side_area_img-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<img src=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/Faculty_LiChingHsieh.jpg\" alt=\"\" \/>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_contact_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\"><a href=\"mailto: liching@dragon.nchu.edu.tw\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\tliching@dragon.nchu.edu.tw<\/a><\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">(04)22840338 #7091(\u8fa6\u516c\u5ba4) #7081(\u5be6\u9a57\u5ba4)<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"cemail\">\u52d5\u690d\u7269\u9632\u6aa2\u75ab\u5927\u6a137\u6a13709\u5ba4<\/span>\r\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t\t<ul class=\"team-manager-popup-items-social-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t\t<div class=\"team_popup_right_side_area-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t<h4><a href=\"https:\/\/orcid.org\/0000-0002-9758-8888\"><img loading=\"lazy\" class=\"wp-image-2595 alignright\" src=\"http:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png\" alt=\"\" width=\"79\" height=\"79\" srcset=\"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-150x150.png 150w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-24x24.png 24w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-36x36.png 36w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948-48x48.png 48w, https:\/\/bif.nchu.edu.tw\/wordpress\/wp-content\/uploads\/2019\/08\/orcid_500x500-e1607582467948.png 190w\" sizes=\"(max-width: 79px) 100vw, 79px\" \/><\/a>\u7c21\u8981\u7d93\u6b77(<a href=\"https:\/\/sites.google.com\/email.nchu.edu.tw\/lchsieh\/personal-information?authuser=0\">\u500b\u4eba\u7db2\u7ad9<\/a>)<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"20%\">\u8077\u7a31<\/th>\n<th width=\"54%\">\u670d\u52d9\u55ae\u4f4d<\/th>\n<th width=\"26%\">\u8d77\u8a16\u5e74\u6708<\/th>\n<\/tr>\n<tr>\n<td>\u526f\u6559\u6388<\/td>\n<td>\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2020\/08 \u2013 \u8fc4\u4eca<\/td>\n<\/tr>\n<tr>\n<td>\u52a9\u7406\u6559\u6388<\/td>\n<td>\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u6240<\/td>\n<td>2011.2-2020.07<\/td>\n<\/tr>\n<tr>\n<td>\u8a2a\u554f\u5b78\u8005<\/td>\n<td>\u7f8e\u570b\u829d\u52a0\u54e5\u5927\u5b78\u751f\u614b\u6f14\u5316\u7cfb<\/td>\n<td>2004.12-2005.11<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb\u5f8c\u7814\u7a76\u54e1<\/td>\n<td>\u4e2d\u592e\u7814\u7a76\u9662\u57fa\u56e0\u9ad4\u4e2d\u5fc3\/\u8cc7\u8a0a\u79d1\u5b78\u7814\u7a76\u6240<\/td>\n<td>2004.8-2011.1<\/td>\n<\/tr>\n<tr>\n<td>\u535a\u58eb<\/td>\n<td>\u570b\u7acb\u4e2d\u592e\u5927\u5b78\u7269\u7406\u5b78<\/td>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u6559\u6388\u8ab2\u7a0b:<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u8ab2\u7a0b\u540d\u7a31<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\n<p class=\"pHead\">\u61c9\u7528\u57fa\u56e0\u9ad4\u5b78\u53ca\u751f\u7269\u8cc7\u8a0a\u5b78\u66a8\u5be6\u7fd2(\u57fa\u8cc7\u6240)\u3001\u4f7f\u7528 R \u8a9e\u8a00\u4ecb\u7d39\u751f\u7269\u7d71\u8a08(\u57fa\u8cc7\u6240)\u3001\u751f\u7269\u8cc7\u6599\u5206\u6790\u7279\u8ad6(\u57fa\u8cc7\u6240)\u3001\u666e\u901a\u7269\u7406\u5b78(\u7269\u7406\u7cfb)\u3001\u666e\u901a\u7269\u7406\u5b78\u5be6\u9a57(\u7269\u7406\u7cfb)<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u7814\u7a76\u4e3b\u984c<\/h4>\n<table class=\"Table-PersonalExp\" width=\"100%\">\n<tbody>\n<tr>\n<th width=\"88%\">\u5be6\u9a57\u5ba4\u7814\u7a76\u65b9\u5411<\/th>\n<\/tr>\n<tr>\n<td class=\"topic\">\u5fae\u6838\u91a3\u6838\u9178\u4e0a\u6e38\u8abf\u63a7\u7db2\u8def\u7684\u6f14\u5316p53\/miR-34 \u7db2\u8def\u4e4b\u6f14\u5316\u4e0a\u7684\u4fdd\u5b88\u6027A \u578b\u6d41\u884c\u6027\u611f\u5192\u75c5\u6bd2\u8840\u51dd\u7d20\u7684\u6f14\u5316<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4><a href=\"https:\/\/sites.google.com\/email.nchu.edu.tw\/lchsieh\/publications?authuser=0\">\u8457\u4f5c&amp;\u7814\u8a0e\u6703\u8ad6\u6587<\/a><\/h4>\n\t\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t<ul class=\"team-manager-free-items-style2-social_media_team-1739\">\r\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\r\n\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-teamprofiles-1739\">\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-title-1739\">\r\n\t\t\t\t\t\t\t\t<a href=\"\" data-featherlight=\"#fl11654893216\">\r\n\t\t\t\t\t\t\t\t\t\u8b1d\u7acb\u9752\t\t\t\t\t\t\t\t<\/a>\r\n\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<div class=\"team-manager-free-items-style2-team-post-1739\">\r\n\t\t\t\t\t\t\t\t\u526f\u6559\u6388\t\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t<p style=\"display:block\" class=\"team-manager-free-items-style2-team-description-1739\">\r\n\t\t\t\t\t\t\t\t\u7814\u7a76\u65b9\u5411:Computational Biology,Evolutionary Biology\r\nComparative Genomics,NGS data analysis\t\t\t\t\t\t\t<\/p>\r\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t<\/div>\r\n\t<div class=\"clearfix\"><\/div><\/p>\n<!-- \/wp:shortcode -->\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-241ac88 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"241ac88\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b02858d\" data-id=\"b02858d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3fd5995 elementor-widget elementor-widget-html\" data-id=\"3fd5995\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<!DOCTYPE html>\r\n<html lang=\"en\">\r\n<head>\r\n    <meta charset=\"UTF-8\">\r\n    <meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\r\n    <title>\u7db2\u9801\u6a19\u984c<\/title>\r\n <style>\r\n  \/* \u6807\u7b7e\u6837\u5f0f *\/\r\n  #div1 {position:relative; width:600px; height:250px; margin: 20px auto 0; }\r\n  #div1 a {position:absolute; top:0px; left:0px; font-family: Microsoft YaHei; color:#fff; font-weight:bold; text-decoration:none; padding: 3px 6px; }\r\n  #div1 a:hover {border: 2px solid #666; background:none; }\r\n\r\n  \/* \u6807\u7b7e\u5b57\u4f53\u6837\u5f0f *\/\r\n  #div1 .blue {color: blue;}\r\n  #div1 .red {color: red;}\r\n  #div1 .orange {color:#F90;}\r\n  #div1 .pink {color: #F6F;}\r\n  #div1 .black {color: #333;}\r\n  #div1 .purple {color: #90F;}\r\n\r\n  \/* \u5176\u4ed6\u6587\u5b57\u6837\u5f0f *\/\r\n  p { font: 18px Microsoft YaHei; text-align: center; color:#999; }\r\n  p a { font-size: 18px; color: #999; }\r\n  p a:hover { color: #333; }\r\n <\/style>\r\n<\/head>\r\n<body>\r\n<main>\r\n<h3 class=\"widget-title\"><span>\u6a19\u7c64\u96f2<\/span><\/h3>\r\n<div id=\"html5-cumulus-eendrf\">\r\n<canvas width=\"250\" height=\"10\" id=\"canvas-eendrf\" style=\"background-color: none;\">\r\n<p>\u4f60\u76ee\u524d\u4f7f\u7528\u7684\u700f\u89bd\u5668\u4e0d\u652f\u63f4 HTML5 \u7684 CANVAS \u6a19\u7c64\u3002<\/p>\r\n<\/canvas>\r\n<div id=\"div1\">\r\n <a href=\"https:\/\/mhholab712.wixsite.com\/mhholab\" class=\"black\">\u85e5\u7269\u8a2d\u8a08\u53ca\u5316\u5b78\u751f\u7269\u6838\u5fc3\u5be6\u9a57\u5ba4<\/a>\r\n <a href=\"http:\/\/predictor.nchu.edu.tw\/ncblab\/\" class=\"red\">\u81ea\u7136\u8a08\u7b97\u8207\u751f\u7269\u8cc7\u8a0a\u6838\u5fc3\u5be6\u9a57\u5ba4<\/a>\r\n <a href=\"https:\/\/megagenome.nchu.edu.tw\/wordpress\/\" class=\"orange\">\u5fae\u751f\u7269\u57fa\u56e0\u9ad4\u6838\u5fc3\u7814\u7a76\u5ba4<\/a>\r\n <a href=\"https:\/\/bertie.igb.nchu.edu.tw\/jhliu\/index.html\" class=\"purple\">\u7d50\u69cb\u751f\u7269\u8cc7\u8a0a\u6838\u5fc3\u5be6\u9a57\u5ba4<\/a>\r\n <a href=\"https:\/\/sites.google.com\/email.nchu.edu.tw\/lchsieh\/personal-information?authuser=0\" class=\"blue\">\u8a08\u7b97\u8207\u6f14\u5316\u57fa\u56e0\u9ad4\u6838\u5fc3\u5be6\u9a57\u5ba4 <\/a>\r\n <a href=\"#\" class=\"pink\">\u690d\u7269\u529f\u80fd\u6027\u57fa\u56e0\u9ad4\u6838\u5fc3\u5be6\u9a57\u5ba4<\/a>\r\n\r\n<\/div>\r\n\r\n<\/div>\r\n<script type=\"text\/javascript\">\r\n        var radius = 120;\r\nvar dtr = Math.PI\/180;\r\nvar d=300;\r\n\r\nvar mcList = [];\r\nvar active = false;\r\nvar lasta = 1;\r\nvar lastb = 1;\r\nvar distr = true;\r\nvar tspeed=1.5;\r\nvar size=300;\r\n\r\nvar mouseX=0;\r\nvar mouseY=0;\r\n\r\nvar howElliptical=1;\r\n\r\nvar aA=null;\r\nvar oDiv=null;\r\n\r\nwindow.onload=function ()\r\n{\r\n var i=0;\r\n var oTag=null;\r\n \r\n oDiv=document.getElementById('div1');\r\n \r\n aA=oDiv.getElementsByTagName('a');\r\n \r\n for(i=0;i<aA.length;i++)\r\n {\r\n  oTag={};\r\n  \r\n  oTag.offsetWidth=aA[i].offsetWidth;\r\n  oTag.offsetHeight=aA[i].offsetHeight;\r\n  \r\n  mcList.push(oTag);\r\n }\r\n \r\n sineCosine( 0,0,0 );\r\n \r\n positionAll();\r\n \r\n oDiv.onmouseover=function ()\r\n {\r\n  active=true;\r\n };\r\n \r\n oDiv.onmouseout=function ()\r\n {\r\n  active=false;\r\n };\r\n \r\n oDiv.onmousemove=function (ev)\r\n {\r\n  var oEvent=window.event || ev;\r\n  \r\n  mouseX=oEvent.clientX-(oDiv.offsetLeft+oDiv.offsetWidth\/2);\r\n  mouseY=oEvent.clientY-(oDiv.offsetTop+oDiv.offsetHeight\/2);\r\n  \r\n  mouseX\/=5;\r\n  mouseY\/=5;\r\n };\r\n \r\n setInterval(update, 30);\r\n};\r\n\r\nfunction update()\r\n{\r\n var a;\r\n var b;\r\n \r\n if(active)\r\n {\r\n  a = (-Math.min( Math.max( -mouseY, -size ), size ) \/ radius ) * tspeed;\r\n  b = (Math.min( Math.max( -mouseX, -size ), size ) \/ radius ) * tspeed;\r\n }\r\n else\r\n {\r\n  a = lasta * 0.98;\r\n  b = lastb * 0.98;\r\n }\r\n \r\n lasta=a;\r\n lastb=b;\r\n \r\n if(Math.abs(a)<=0.01 && Math.abs(b)<=0.01)\r\n {\r\n  return;\r\n }\r\n \r\n var c=0;\r\n sineCosine(a,b,c);\r\n for(var j=0;j<mcList.length;j++)\r\n {\r\n  var rx1=mcList[j].cx;\r\n  var ry1=mcList[j].cy*ca+mcList[j].cz*(-sa);\r\n  var rz1=mcList[j].cy*sa+mcList[j].cz*ca;\r\n  \r\n  var rx2=rx1*cb+rz1*sb;\r\n  var ry2=ry1;\r\n  var rz2=rx1*(-sb)+rz1*cb;\r\n  \r\n  var rx3=rx2*cc+ry2*(-sc);\r\n  var ry3=rx2*sc+ry2*cc;\r\n  var rz3=rz2;\r\n  \r\n  mcList[j].cx=rx3;\r\n  mcList[j].cy=ry3;\r\n  mcList[j].cz=rz3;\r\n  \r\n  per=d\/(d+rz3);\r\n  \r\n  mcList[j].x=(howElliptical*rx3*per)-(howElliptical*2);\r\n  mcList[j].y=ry3*per;\r\n  mcList[j].scale=per;\r\n  mcList[j].alpha=per;\r\n  \r\n  mcList[j].alpha=(mcList[j].alpha-0.6)*(10\/6);\r\n }\r\n \r\n doPosition();\r\n depthSort();\r\n}\r\n\r\nfunction depthSort()\r\n{\r\n var i=0;\r\n var aTmp=[];\r\n \r\n for(i=0;i<aA.length;i++)\r\n {\r\n  aTmp.push(aA[i]);\r\n }\r\n \r\n aTmp.sort\r\n (\r\n  function (vItem1, vItem2)\r\n  {\r\n   if(vItem1.cz>vItem2.cz)\r\n   {\r\n    return -1;\r\n   }\r\n   else if(vItem1.cz<vItem2.cz)\r\n   {\r\n    return 1;\r\n   }\r\n   else\r\n   {\r\n    return 0;\r\n   }\r\n  }\r\n );\r\n \r\n for(i=0;i<aTmp.length;i++)\r\n {\r\n  aTmp[i].style.zIndex=i;\r\n }\r\n}\r\n\r\nfunction positionAll()\r\n{\r\n var phi=0;\r\n var theta=0;\r\n var max=mcList.length;\r\n var i=0;\r\n \r\n var aTmp=[];\r\n var oFragment=document.createDocumentFragment();\r\n \r\n \/\/\u00cb\u00e6\u00bb\u00fa\u00c5\u00c5\u00d0\u00f2\r\n for(i=0;i<aA.length;i++)\r\n {\r\n  aTmp.push(aA[i]);\r\n }\r\n \r\n aTmp.sort\r\n (\r\n  function ()\r\n  {\r\n   return Math.random()<0.5?1:-1;\r\n  }\r\n );\r\n \r\n for(i=0;i<aTmp.length;i++)\r\n {\r\n  oFragment.appendChild(aTmp[i]);\r\n }\r\n \r\n oDiv.appendChild(oFragment);\r\n \r\n for( var i=1; i<max+1; i++){\r\n  if( distr )\r\n  {\r\n   phi = Math.acos(-1+(2*i-1)\/max);\r\n   theta = Math.sqrt(max*Math.PI)*phi;\r\n  }\r\n  else\r\n  {\r\n   phi = Math.random()*(Math.PI);\r\n   theta = Math.random()*(2*Math.PI);\r\n  }\r\n  \r\n  mcList[i-1].cx = radius * Math.cos(theta)*Math.sin(phi);\r\n  mcList[i-1].cy = radius * Math.sin(theta)*Math.sin(phi);\r\n  mcList[i-1].cz = radius * Math.cos(phi);\r\n  \r\n  aA[i-1].style.left=mcList[i-1].cx+oDiv.offsetWidth\/2-mcList[i-1].offsetWidth\/2+'px';\r\n  aA[i-1].style.top=mcList[i-1].cy+oDiv.offsetHeight\/2-mcList[i-1].offsetHeight\/2+'px';\r\n }\r\n}\r\n\r\nfunction doPosition()\r\n{\r\n var l=oDiv.offsetWidth\/2;\r\n var t=oDiv.offsetHeight\/2;\r\n for(var i=0;i<mcList.length;i++)\r\n {\r\n  aA[i].style.left=mcList[i].cx+l-mcList[i].offsetWidth\/2+'px';\r\n  aA[i].style.top=mcList[i].cy+t-mcList[i].offsetHeight\/2+'px';\r\n  \r\n  aA[i].style.fontSize=Math.ceil(12*mcList[i].scale\/2)+8+'px';\r\n  \r\n  aA[i].style.filter=\"alpha(opacity=\"+100*mcList[i].alpha+\")\";\r\n  aA[i].style.opacity=mcList[i].alpha;\r\n }\r\n}\r\n\r\nfunction sineCosine( a, b, c)\r\n{\r\n sa = Math.sin(a * dtr);\r\n ca = Math.cos(a * dtr);\r\n sb = Math.sin(b * dtr);\r\n cb = Math.cos(b * dtr);\r\n sc = Math.sin(c * dtr);\r\n cc = Math.cos(c * dtr);\r\n}\r\n        <\/script>\r\n    <\/main>\r\n<\/body>\r\n<\/html>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u7db2\u9801\u6a19\u984c \u6a19\u7c64\u96f2 \u4f60\u76ee\u524d\u4f7f\u7528\u7684\u700f\u89bd\u5668\u4e0d\u652f\u63f4 HTML5 \u7684 CANVAS \u6a19\u7c64\u3002 \u85e5\u7269\u8a2d\u8a08\u53ca\u5316\u5b78\u751f\u7269\u6838\u5fc3\u5be6\u9a57\u5ba4 &#8230; <a title=\"\u8b1d\u7acb\u9752\" class=\"read-more\" href=\"https:\/\/bif.nchu.edu.tw\/wordpress\/team_mf\/%e8%ac%9d%e7%ab%8b%e9%9d%92\/\" aria-label=\"\u95b1\u8b80\u3008\u8b1d\u7acb\u9752\u3009\u5168\u6587\">\u95b1\u8b80\u5168\u6587<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/pages\/1011"}],"collection":[{"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/comments?post=1011"}],"version-history":[{"count":68,"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/pages\/1011\/revisions"}],"predecessor-version":[{"id":3630,"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/pages\/1011\/revisions\/3630"}],"wp:attachment":[{"href":"https:\/\/bif.nchu.edu.tw\/wordpress\/wp-json\/wp\/v2\/media?parent=1011"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}