國立中興大學基因體暨生物資訊學研究所

　　

　　 　　

　　　　　　　

　　　　　　　

　　　　　　　

基因體暨生物資訊學研究所

Graduate Institute of Genomics and Bioinformatics

Chinese
English

興大首頁

National Chung Hsing University

醫科博班

Doctoral Program in Medical Biotechnology

生命科學院

College of Life Sciences

Chen, Yu-Ting

Experience

Title Department Period
Associate Professor NCHU, Institute of Genomics and Bioinformatics 2019/08-present
Assistant Professor NCHU, Institute of Genomics and Bioinformatics 2013/03-2019-07
Section Director NCHU, Biotechnology Center Reference and Consultation Section 2008/08 – 2009-03
Assistant Professor NCHU, Biotechnology Center 2008/08 – 2009-03
Assistant Professor NCHU, Biotechnology Center 2006/08 – 2008/07
Adjunct Assistant Professor Hsing Wu University, General Education Center 2005/09 – 2006/06
Visiting Scholar United States Department of Agriculture 2005/03 – 2005/08
Postdoctoral Research Fellow Academia Sinica, Institute of Plant and Microbial Biology 2003/03 – 2006/07
PhD National Defense Medical Center, Graduate Institute of Life Sciences 1995/08 – 2003/02
M.S. TTU,  Department of Chemical Engineering 1993/09 – 1995/06
B.S. TTU, Department of Chemical Engineering and Biotechnology 1989/09 – 1993/06

Research

Research Interests
  1. Molecular biology
  2. Plant Transgenic
  3. Plant Functional Genomics
  4. Bioenergy

Lectures:

Course

Biochemistry, Experimental Biochemistry, Applied Genomics and Bioinformatics: Lecture and Experiment, Applied Genomics and Bioinformatics: Lecture and Experiment,Functional Biology
,Plant Gene Cloning Techniques Workshop, Special Topics in Plant Gene Transformation, To Construct and Analyze on Genomics Database,Special Topics in Lipid Biotechnology

Publications

Journal (*Corresponding author)
  1. Li JR, Liu CC, Sun CH, Chen YT*: Plant stress RNA-seq Nexus: a stress-specific transcriptome database in plant cells. BMC Genomics(2019)
  2. Chen YT†, Chang CC†, Chen CW, Chen KC, Chu YW: MADS-box gene classification in angiosperms by clustering and machine learning approaches. Front Genet(2019)
  3. Liu CH, Chen YT, Hou MH, Hu NJ, Chen CS*, Shaw JF*: Crystallographic analysis of the Staphylococcus epidermidis lipase involved in esterification in aqueous solution. Acta Cryst(2018)
  4. Chen YT†, Hong PF†, Wen L†, Lin CT*: Molecular cloning and characterization of a thioredoxin from Taiwanofungus camphorate. Bot Stud(2014)
  5. Huang CY†, Chen YT†, Wen L†, Sheu DC, Lin CT*: A peroxiredoxin cDNA from Taiwanofungus camphorata: role of Cys31 in dimerization. Mol Biol Reports(2014)
  6. Chuang HH, Cheng CY, Chen YT*, Shaw JF*: Novel highly active recombinant glutaredoxin from Chlorella sorokiniana T-89. J Agric Food Chem(2014)
  7. Chuang HH, Cheng CY, Chen YT, Shaw JF*. (2014) Novel Highly Active Recombinant Glutaredoxin from Chlorella sorokiniana T-89. J Agric Food Chem. 2014 Jan 14. J Agric Food Chem. 2014 Jan 29;62(4):927-933.
  8. Huang CY#,Chen YT, Wen L#, Sheu DC, Lin CT*. (2014) A peroxiredoxin cDNA from Taiwanofungus camphorata: role of Cys31 in dimerization. Mol Biol Rep. 41(1):155-164.
  9. Chen YT, Chin-Hui Shen, Wen-Dar Lin, Hsiu-An Chu, Bau-Lian Huang, Ching-I Kuo, Kai-Wun Yeh*, Li-Chun Huang*, and Ing-Feng Chang* (2013) Small RNAs of Sequoia sempervirens during rejuvenation and phase change. Plant Biology 15(1):27-36 (SCI)
  10. Ko CY, Lai YL, Liu WY, Lin CH, Chen YT, Chen LF, Lin TY*, Shaw JF*. (2012) Arabidopsis ENDO2: Its catalytic role and requirement of N-glycosylation for function. J Agric Food Chem. 60 (20), 5169–5179 (SCI)
  11. Chen PT, Chiang CJ, Chen YT, Lin HC, Liu CH, Chao YP*, Shaw JF*. (2012) Strategy for stable and high-level expression of recombinant trehalose synthase in Escherichia coli. J Agric Food Chem. 60 (23), 6063–6068 (SCI)
  12. Chu HA, Chang IF, Shen CH, Chen YT, Wang HT, Huang LC*, and Yeh KW* (2012) Photosynthetic properties and photosystem stoichiometry of in vitro-grown juvenile, adult, and rejuvenated Sequoia sempervirens (D. Don) Endl. Botanical Studies. 53:3.1 (SCI)
  13. Huang LC, Hsiao LJ, Pu SY, Kuo CI, Huang BL, Tseng TC, Huang HJ*, Chen YT(2012) DNA Methylation and genome rearrangement characteristics of Phase change in cultured shoots of Sequoia sempervirens. Physiola Planta 145: 360-368.(SCI)
  14. Chang PC, Pan WJ, Chen CW, Chen YT and Chu YW* (2012) DEsi: A design engine of siRNA that integrates SVMs prediction and feature filters. Biocat Agric Biotech 1: 129-134.
  15. Chuang HH, Chen PT, Wang WN, Chen YT*, Shaw JF* (2011) Functional proteomic analysis of rice bran esterases/lipases and characterization of a novel recombinant esterase. J Agric Food Chem. 2011 Mar 9;59(5):2019-25.
  16. Chang IF, Chen PJ, Shen CH, Hsieh TJ, Hsu YW, Huang BL, Kuo CI, Chen YT, Chu HA, Yeh KW, Huang LC (2010) Proteomic profiling of proteins associated with the rejuvenation of Sequoia sempervirens (D. Don) Endl. Proteome Science 8:64.
  17. Chen YT, Fang QS, Chiang CH, Yeh SD, Wu HW, Yu TA (2010) Transgenic Eustoma grandiflorum expressing the bar gene are resistant to herbicide Basta®. PCTOC: J Plant Biotech. 102 (3): 347-356. (SCI)
  18. Liau YJ, Chen YT, Lin CY, Huang JK, Lin CT (2010) Characterisation of 2-Cys peroxiredoxin isozyme (Prx1) from Taiwanofungus camphorata (Niu-chang-chih): Expression and enzyme properties. Food Chem. 119: 154-160. (SCI)
  19. Chen YT, Chen LFO, Shaw JF* (2008) Senescence associated genes in harvested broccoli florets, Plant Science 175, 137-144. (SCI)
  20. Chen YT, Chen HH, Uchimiya H, Chu MJ, Chiou YS, Shaw JF, Huang LC (2007) Prolonging the longevity of Cymbidium flowers through genetic transformation. Acta Horticulture. 738: 545-548.
  21. Lee, LC, Chen YT, Yen CC, Chiang TCY, Tang SJ, Lee GC* and Shaw JF* (2007) Altering the substrate specificity of Candida rugosa LIP4 by engineering the substrate binding sites. J. Agric. Food Chem. 55(13); 5103-5108. (SCI)
  22. Chen YT, Hsu LH, Huang IP, Tsai TC, Lee GC, and Shaw JF* (2007) Gene Cloning and Characterization of a Novel Recombinant Antifungal Chitinase from Papaya (Carica papaya) J. Agric. Food Chem. 55:714-722. (SCI)
  23. Wang YT, Yang CY, Chen YT, Lin Y and Shaw JF* (2004) Characterization of senescence-associated proteases in postharvest broccoli florets. Plant Physiol. Biochem. 42:663-670. (SCI)
  24. Chen LFO, Huang JY, Wang YH, Chen YT and Shaw JF* (2004) Ethylene insensitive and post-harvest yellowing retardation in mutant ethylene response sensor (boers) gene transformed broccoli (Brassica olercea var. italica) Mol. Breed. 14:199-213. (SCI)
  25. Yang CY, Chu FH, Wang YT, Chen YT, Yang SF, and Shaw JF* (2003) Novel broccoli 1-aminocyclopropane-1-carboxylate oxidase gene (Bo-ACO3) associated with the late stage of postharvest floret senescence. J. Agric. Food Chem. 51:2569-2575. (SCI)
  26. Chen YT, Lee IR, Yang CY, Wang YT, Yang SF, and Shaw JF* (2003) A novel papaya 1-aminocyclopropane-1-carboxylate oxidase gene (CP-ACO2) associated with late-stage senescence. Plant Science 164:531-540. (SCI)
  27. Lin CT, Lin MT, Chen YT and J.F. Shaw*. 1995. The gene structure of Cu/Zn-superoxide dismutase from sweet potato. Plant Physiol. 108: 827-828. (SCI)
  28. Lin CT, Lin MT, Chen YT and J.F. Shaw*. 1995. Subunit interaction enhances enzyme activity and stability of cytosolic Cu-Zn-superoxide dismutase. Plant Mol. Biol. 28: 303-311. (SCI)

 

Conference (*Invited speaker)
  1. Lin TW, Kou YT, Liu CH, Lin WT, Chen YT*: Build up the highest astaxanthin production platform by using optima cultural condition analysis of Chlorella. sp. DT and the tr ansgenic approach. 14th International Symposium on Agricultural Biocatalysis and Biotechnology
  2. Liu CH, Chen YT, Chen CS, Shaw JF: Lipase cloned from Staphylococcus epidermidis: crystallization and X-ray crystallographic analysis. 13th International Symposium on Agricultural Biocatalysis and Biotechnology
  3. Liu JH*, Nien CY, Chang CW, Hong CS, Chang SW, Chen YT and Shaw JF: Contribution of surface residues on the thermostability of the trehalose synthase from Picrophilus torridus. 13th International Symposium on Agricultural Biocatalysis and Biotechnology
  4. Liu CH, Chen PT, Hsu FY, Chen YT, Chen CS, Shaw JF: Thermal stable esterase (rGtEst1) of Geobacillus thermodnitrificans PS01.12th Cross-Strait International Conference on Symposium on Plant Molecular Biology and Biotechnology
  5. ZengWW, Chen TC, Wang SY, Liu CH, Chen YT*: Identification of an anti-proliferative 2,4-dimethoxy-6-methylbenzene- 1,3-diol from Antrodia cinnamomea. 12th Cross-Strait International Conference on Symposium on Plant Molecular Biology and Biotechnology
  6. Liu JH, Chuang HH, Chen TW, Shaw JF, and Chen YT*: Catalytic related amino acid of glutaredoxin from Chlorella sorokiniana 12th Cross-Strait International Conference on Symposium on Plant Molecular Biology and Biotechnology
  7. Zeng WW, Wang SY, Liu CH, Chen YT*: Identification of a dual-function phenolic compound with anti-oxidant and anti-proliferative activities in Antrodia cinnamome. 2016中草藥在抗老化植物新藥之應用趨勢研討會
  8. Chiu CM, Chao HY, Chen YT*: Physiological Function of GDSL-lipase in Rice (Oryza sativa). The 10th International Symposium on Agricultural Biocatalysis and Biotechnology
  9. Hsu FY, Liu CH, Chen YT, Chen PT, Chen CS, Shaw JF*: Gene analysis and Biochemical Characterization of a Novel Recombinant Lipase rGtLIP1 from Geobacillus thermodenitrificans PS01. The 10th International Symposium on Agricultural Biocatalysis and Biotechnology
  10. Chao HY, Chen YT*: Rice GDSL Lipase may Promote Grain Yield and Salt Resistance. The 10th International Symposium on Agricultural Biocatalysis and Biotechnology
  11. Huang YH, Zeng WW, Wang WN, Chen YT*: Improvement of the Antioxidant Activity of Antrodia cinnamomea by Medium Modification and Adding Methanolic Extract of Cinnamomum kanehirae The 10th International Symposium on Agricultural Biocatalysis and Biotechnology
  12. Kuo YT, Lee JH, Chen YT*: Beta-Carotene Ketolase of Chlorella. sp. DT Cloning and Overexpression for Astaxanthin Production in Transgenic Plant. The 10th International Symposium on Agricultural Biocatalysis and Biotechnology
  13.  Hsu-Han Chuang, Chen YT and Jei-Fu Shaw (2013) (Invited Lecture) Study the gene functions of rice lipases/esterases by using functional proteomics approaches. The 9th International Symposium on Agricultural Biocatalysis and Biotechnology. Piešťany, Slovak Republic, October 13 – 16, 2013.
  14.  Lee JH, Chen YT, Chuang HH, Chiu JM (2012) Cloning and characterization cinnamyl alcohol dehydrogenase from Chlorella sorokiniana T89. International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Excellent Poster Award)
  15.  Zeng WW, Wang WN, Shaw JF*, and Chen YT (2012) Improvement of the antioxidant activity of Antrodia Cinnamomea by medium modification and adding methanolic extract of Cinnamomum kanehirae leaf. International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Excellent Poster Award)
  16.  Cheng CY, Shaw JF*, Chen YT (2012) Cloning and characterization of glutaredoxin from Chlorella sorokiniana T89. International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Excellent Poster Award)
  17.  Chen PT, Chiang CJ, Chen YT, Lin HC, Liu CH, Chao YP* and Shaw JF* (2012) Chromosome engineering Escherichia coli host for the efficient production of Picrophilus torridus trehalose synthase. International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22. (Best Poster Award)
  18.  Chuang HH, Liu CH, Chen YTand Shaw JF (2012) (Invited Lecture) Study rice estersaes/lipases by functional proteomics approach. International Symposium on Oil Food Biotechnology. Kao-Hsiung, Taiwan, Dec 21-22.
  19.  Jei-Fu Shaw* and Chen YT (2012) Biocatalysis in Agricultural Biotechnology. BIT’s 3rd Inaugural Symposium on Enzymes & Biocatalysis-2012 (SEB-2012), Xi’an, China. April, 25-28.
  20.  Chuang HH, Chen YT and Shaw JF (2011) (Invited lecture) Functional proteomic analysis and characterization of a novel rice bran esterases/lipases. The 7th International Symposium on Agricultural Biocatalysis and Biotechnology. Kyoto, Japan. Oct 10-13.
  21. Bezirganoglu I, Chen YT, Chuang HH, Hwang SY, Shaw JF* (2010) Improve the resistance to Rhizoctonia solani of transgenic melon (Cucumis melo silver light L.) plants with overexpressing chitinases. The 6th International Symposium on Biocatalysis and Biotechnology. Seoul, Korea. Nov 17-19.
  22. Yu TA, Chen YT*, Chiang CH, Wang PT, Chang YL, Shih HD, Yeh SD, Shaw JF* (2010) (Invited lecture) Transgenic melon plants expressing antifungal AFP3 protein develop resistance to fungal diseases. The 6th International Symposium on Biocatalysis and Biotechnology. Seoul, Korea. Nov 17-19.
  23. Chuang HH, Chen YT*, Shaw JF* (2010) (Invited lecture) Characterization and application of the recombinant rice bran lipase. 2010 Lipid Science Division Symposium at the Annual Meeting of Korean Society of Food Science and Technology. Inchon, Korea. Jun 16-18.
  24. Bezirganoglu I, Chen YT, Chang YL, Shaw JF* (2009) Melon transformation using antifungal protein & chitinase gene to against fungal disease Rhizoctania Solani. The 5th International Symposium on Biocatalysis and Biotechnology. Taiwan. Nov 18-20. (Excellent Poster Award)
  25. Chen YT and Shaw JF (2008) (Invited lecture) NCHU/CUHK Bilateral Symposium on Plant Biotechnology. Dec 17-23, Taichung, Taiwan.
  26. Chen YT and Shaw JF (2007) (Invited Speech) Functional genes and biotechenology. The Sixth Cross-Strait Symposium on Plant Molecular Biology and Biotechnology. Jul. 3-7, Hong Kong, China
  27. Chen YT and J.F. Shaw (2007) (Organizer and Invited Speech) Papaya functional genomics and biotechnological application. 3rd Internatrional Symposium on Biocatalysis amd Biotechnology. Nov. 28-30, Taichung, Taiwan
  28. Lee LC, Chen YT, Yen CC, Tang SJ, Lee GC and Shaw JF (2007) Altering the Substrate Specificity of Candida rugosa LIP4 by Engineering the Substrate-Binding Sites. 3rd Internatrional Symposium on Biocatalysis and Biotechnology. Nov. 28-30, Taichung, Taiwan.
  29. Chen YT, and Shaw JF (2007) (Organizer and Invited Speech) Papaya functional genomics and biotechnological application. 3rd Internatrional Symposium on Biocatalysis amd Biotechnology. Nov. 28-30, Taichung, Taiwan
  30. Chen YT and Shaw JF (2007) (Invited Speech) The Application of Functional Genomics Study on Papaya and Its Implication in Fruit Industry. The International Symposium on Bio-industry Development and Post-graduate Workshop, Dec. 4-7, Taichung, Taiwan.
  31. Chou YF, Chen HH, Chen YT, Shaw JF (2006) (Invited oral presentation) Molecular characterization of three broccoli chloropyllase genes, differentially regulated by ethylene. 7th International Symposium on the Plant Hormone Ethylene. June 18-22, Pisa, Italy.
  32. Chen YT, Huang IP, Shu LH, Shaw JF (2006) Cloning and characterization of ethylene-upregualted chitinase from papaya. 7th International Symposium on the Plant Hormone Ethylene. June 18-22, Pisa, Italy.
  33. Chen YT, Chen HH, Uchimiya H, Chu MJ, Chiou YS, Shaw JF, Huang LC (2005) (Invited oral presentation) Prolonging the longevity of Cymbidium flowers through genetic transformation. Proceeding of ISHS on the 3rd International Symposium on Biotechnology of Temperate Fruit Crops and Tropic species. October 10-14, USA.
  34. Chen YT (2005) (Invited speech) Papaya fruit maturation and ripening associated gene. April 19, USDA, Beltsville, USA.
  35. Chen YT, Chou TL, Yang CY, Kao CY, Lai HY, Jian WT, Shaw JF (2004) (Invited oral presentation) Papaya fruit maturation and ripening associated gene. International Symposium on Plant Functional Genomics. WA-06, June 6-11, Verona, Italy.
  36. Chen YT, Chou TL, Yang CY, Kao CY, Lai HY, Jian WT, Shaw JF (2003) Papaya fruit maturation and ripening associated gene. International Symposium on Plant Functional Genomics. A17, Nov 17-19, Taipei, Taiwan.
  37. Chen YT, Lee IR, Yang CY, Shaw JF (2001) Differential expression of the 1-aminocyclopropane-1-carboxylate oxidase gene family of papaya. 第十六屆生物醫學聯合年會生物化學及分子生物學學會壁報論文 P99, Mar, 24-25, Taipei, Taiwan。
  38. Chen YT and Shaw JF (2001) (Invited lecture) Papaya ACC oxidases. The 2nd Internationtional Symposium on Biotechnology of Tropical and Subtropical Species. Nov. 5-9.Taipei, Taiwan.
  39. Chen YT, Lee IR, Yang CY, Shaw JF (2000) Differential expression of the papaya 1-aminocyclopropane-1-carboxylate oxidase gene family. Symposium on Plant Sciences for 21st Century. C10. pp56. Nov. 9-10, Taipei, Taiwan.
  40. Yang CY, Lin Y, Chu FH, Chen YT, Lee YR, Shaw JF (2000) Senescemce associated genes of broccoli florets. Symposium on Plant Sciences for 21st Century. B5. pp34. Nov. 9-10, Taipei, Taiwan.
  41. Chen YT and Lin CT (1995) Purification and characterization of two isozymes of Cu/Zn-SOD from sweet potota tuberous root.農化學會第三十三次大會論文宣讀，1995。
  42. Chen YT and Lin CT (1995) Cloning and structure analysis of Cu/Zn-SOD gene from sweet potato. 農化學會第三十三次大會論文宣讀，1995。
  43. Chen YT and Lin CT (1995) Over expression of sweet potato cytosolic Cu/Zn-SOD in E. coli. 農化學會第三十三次大會論文宣讀，1995。
Books
  1. 陳玉婷、 陳榮芳、黃麗春、蕭介夫 (2004) 植物基因轉殖在植物保鮮儲運上之應用，教育部植物生物技術教學資源中心主編—植物基因轉殖之原理與應用，2004，p243-254。

 

Patent
  1. Shaw, J.F.,Y.T. Chen, L.H. Hus. Novel chitinase and use thereof. U.S.A patent US7670820, Jan 14, 2008-Jan 17, 2028 (March 2, 2010)