PEOPLE & RESEARCH

師資與研究

國立中興大學基因體暨生物資訊學研究所的研究橫跨基因體學、生物資訊、結構與分子生物學,以及生物科技與生醫應用。我們從不同尺度與方法探索生命科學問題,並結合實驗研究、計算分析與資料科學。

Research at the Graduate Institute of Genomics and Bioinformatics spans genomics, bioinformatics, structural and molecular biology, biotechnology, and biomedical applications. Our faculty explore biological questions across different scales and perspectives, integrating experimental research with computational analysis and data science.

FACULTY

師資 Faculty

本所師資的研究涵蓋基因體學、生物資訊、分子與結構生物學、生物科技與生醫應用,並結合實驗與計算方法探索生命科學問題。

Our faculty work across genomics, bioinformatics, molecular and structural biology, biotechnology, and biomedical applications, integrating experimental and computational approaches to address biological questions.

侯明宏

Ming-Hon Hou

Lifetime Distinguished Professor
Director, Biotechnology Center
Director, Doctoral Program in Medical Biotechnology
Director, Doctoral Program in Microbial Genomics

Drug Design and Chemical Biology Core Lab

DRUG DESIGN · STRUCTURAL BIOLOGY · BIOPHYSICS · PROTEIN ENGINEERING

研究核酸與蛋白質的分子結構及其與小分子的交互作用,結合結構生物學、生物物理與蛋白質工程,應用於藥物設計與疾病診斷工具的開發。

Research on the molecular structures of nucleic acids and proteins and their interactions with small molecules, combining structural biology, biophysics, and protein engineering for drug design and the development of diagnostic tools.

Contact 聯絡資訊
Email mhho@dragon.nchu.edu.tw
Office (04)2284-0338 #7011
Laboratory (04)2284-0338 #7121
Location 動植物防檢疫大樓 7 樓 701 室

Email · Website · ORCID

朱彥煒

Yen-Wei Chu

Lifetime Distinguished Professor

Natural Computing & Bioinformatics Laboratory

BIOINFORMATICS · ARTIFICIAL INTELLIGENCE · PRECISION MEDICINE · BIG DATA

發展生物資訊演算法、人工智慧與大數據分析方法,應用於生醫資料分析、精準醫療與智慧農業,並建立機器學習與生物資訊預測模型。

Development of bioinformatics algorithms, artificial intelligence, and big-data approaches for biomedical data analysis, precision medicine, and smart agriculture, including machine-learning methods and predictive models for biological applications.

Contact 聯絡資訊
Email ywchu@nchu.edu.tw
Office (04)2284-0338 #7041
Laboratory (04)2284-0338 #7161
Location 動植物防檢疫大樓 7 樓 704 室

Email · Website · ORCID

陳盈璁

Ying-Tsong Chen

Professor
Director, Graduate Institute of Genomics and Bioinformatics
Adjunct Investigator, National Health Research Institutes

Microbial Genomics Laboratory

MICROBIAL GENOMICS · ANTIMICROBIAL RESISTANCE · PATHOGEN EVOLUTION · LONG-READ SEQUENCING

利用基因體定序、生物資訊與微生物學方法研究微生物基因體、抗生素抗藥性與病原體演化,包括抗藥性與可移動遺傳因子的傳播、新興病原體的演化與疫情,以及宿主與微生物的交互作用。

Genomic, bioinformatic, and microbiological approaches to microbial genomics, antimicrobial resistance, and pathogen evolution, including the spread of antimicrobial resistance and mobile genetic elements, the evolution and epidemiology of emerging pathogens, and host–microbe interactions.

Contact 聯絡資訊
Email onion@nchu.edu.tw
Office (04)2284-0338 #7101
Laboratory (04)2284-0338 #7111
Location 動植物防檢疫大樓 7 樓 711 室

Email · Website · ORCID · Google Scholar

陳玉婷

Yu-Ting Chen

Associate Professor
Executive Officer, International Doctoral Program in Integrative and Innovative Biotechnology

Plant Functional Genomics Laboratory

PLANT GENOMICS · PLANT BIOTECHNOLOGY · PROTEOMICS · SYNTHETIC BIOLOGY

結合基因體、蛋白質體與分子生物學方法研究植物功能基因,並將研究應用於分子育種、植物生物技術與高價值代謝物的生產。

Genomic, proteomic, and molecular biology approaches to the study of functional genes in plants, with applications in molecular breeding, plant biotechnology, and the production of valuable metabolites.

Contact 聯絡資訊
Email yuting@dragon.nchu.edu.tw
Office (04)2284-0338 #7021
Laboratory (04)2284-0338 #7151
Location 動植物防檢疫大樓 7 樓 702 室

Email · ORCID

劉俊宏

Jyung-Hurng Liu

Associate Professor

Structural Bioinformatics Laboratory

STRUCTURAL BIOLOGY · X-RAY CRYSTALLOGRAPHY · PROTEIN STRUCTURE · MOLECULAR BIOLOGY

利用 X 光晶體學、生物物理與生物資訊方法研究生物巨分子的結構與功能,解析蛋白質結構、分子交互作用及其生物學機制,並應用於酵素工程、抗藥性與藥物開發。

Structural and functional studies of biological macromolecules using X-ray crystallography, biophysics, and bioinformatics, with emphasis on protein structures, molecular interactions, and their biological mechanisms, and applications in enzyme engineering, antimicrobial resistance, and drug development.

Contact 聯絡資訊
Email jhliu@nchu.edu.tw
Office (04)2284-0338 #7181
Laboratory (04)2284-0338 #7131
Location 動植物防檢疫大樓 7 樓 718 室

Email · Website · ORCID

謝立青

Li-Ching Hsieh

Associate Professor

Computational and Evolutionary Genomics Laboratory

COMPUTATIONAL BIOLOGY · EVOLUTIONARY GENOMICS · TRANSCRIPTOMICS · MACHINE LEARNING

運用次世代定序、生物資訊與機器學習分析基因體與轉錄體資料,研究 microRNA 的調控與演化、基因表現調控,以及不同生物系統中的基因體與轉錄體變異。

Genomic and transcriptomic analyses using next-generation sequencing, bioinformatics, and machine learning, with particular interests in microRNA regulation and evolution, gene regulation, and genomic and transcriptomic variation across diverse biological systems.

Contact 聯絡資訊
Email liching@dragon.nchu.edu.tw
Office (04)2284-0338 #7091
Laboratory (04)2284-0338 #7081
Location 動植物防檢疫大樓 7 樓 709 室

Email · Website · ORCID

JOINT & ADJUNCT FACULTY

合聘與兼任師資 Joint & Adjunct Faculty

合聘師資 Joint Faculty

蔡孟勳

Professor

Bioinformatics · Biochemistry · Molecular Biology

Contact 聯絡資訊
Email mht@nchu.edu.tw
Office (04)2284-0864 #666
Location 社管大樓 6 樓 666 室
Website Faculty Website

洪慧芝

Professor

Protein Structure · Protein Function

Contact 聯絡資訊
Email hchung@dragon.nchu.edu.tw
Office (04)2284-0416 #616
Location 生命科學大樓 617 室
Website Faculty Website

鄭旭辰

Assistant Professor

Embryonic Development · Cell Differentiation · Signal Transduction · Organ Development and Evolution

Contact 聯絡資訊
Email hcheng@dragon.nchu.edu.tw
Office (04)2284-0416 #504
Location 生命科學大樓 517 室
Website Faculty Website

趙裕展

Professor

Insect Virus Engineering · Vaccinology · Protein Engineering

Contact 聯絡資訊
Email mbycchao@gmail.com
Office (04)2284-0813 #413
Website Faculty Website

劉明容

Associate Research Fellow

Plant Gene Expression · Translational Regulation · Environmental Stress Responses

Contact 聯絡資訊
Email mjliu@gate.sinica.edu.tw
Office (06)216-6857
Laboratory (06)216-6858
Location 中央研究院南部院區研究大樓 214 室
Website Faculty Website

李文雄

Professor

Evolutionary Biology · Genetics · Genomics

Contact 聯絡資訊
Email whli@gate.sinica.edu.tw
Office (02)2787-2256
Laboratory (02)2787-2257
Location 中央研究院生物多樣性研究中心,台北市南港區研究院路二段 128 號,跨領域 A203
Website Faculty Website

張芸瑄

Professor

Mental Health and Aging · Neuropsychology · Clinical Psychology · Mental Health and Healthcare Sciences

Contact 聯絡資訊
Email psycyh.ncku@gmail.com
Office (06)235-3535 #5976
Website Faculty Website

郭博昭

Professor

Neuroscience · Computer Science · Physiology · Informatics · Translational Medicine

Contact 聯絡資訊
Email tbjkuo@ym.edu.tw
Office (02)2826-7058
Website Faculty Website

王秉彥

Professor

Thoracic Surgery · Medicine

Contact 聯絡資訊
Email 156283@cch.org.tw
Website Faculty Website

林聖皓

Associate Professor

Pulmonary Medicine · Medicine

Contact 聯絡資訊
Email 112364@cch.org.tw
Website Faculty Website

兼任師資 Adjunct Faculty

蕭自宏

Adjunct Assistant Professor

Bioinformatics

Contact 聯絡資訊
Email thsiao@vghtc.gov.tw
Office (04)2359-2525 #4426
Location 臺中榮總醫學研究部 研究大樓 4 樓 418 研究室
Website Faculty Website

林慶雄

Adjunct Associate Professor

Pulmonary Medicine · Medicine

Contact 聯絡資訊
Email 47822@cch.org.tw
Website Faculty Website

RESEARCH AREAS

研究領域 Research Areas

本所的研究從基因體與分子結構出發,結合生物資訊、人工智慧與實驗方法,探索生命系統的演化、功能與調控,並進一步連結生物科技、醫學與跨領域應用。

Our research connects genomics and molecular biology with bioinformatics, artificial intelligence, and experimental approaches to understand the evolution, function, and regulation of biological systems, while extending these discoveries toward biotechnology, medicine, and interdisciplinary applications.

01

Genomics & Evolution
基因體與演化

We investigate genomes and transcriptomes to understand biological diversity, adaptation, gene regulation, and evolutionary change across microorganisms, pathogens, plants, and other biological systems.

透過基因體與轉錄體研究,探索微生物、病原體、植物及其他生物系統的多樣性、適應、基因調控與演化變遷。

02

Bioinformatics, AI & Data Science
生物資訊、人工智慧與資料科學

We develop computational, statistical, and machine-learning approaches to analyze complex biological and biomedical data, discover patterns, construct predictive models, and transform large-scale data into biological insight.

發展計算、統計與機器學習方法,分析複雜的生物與生醫資料,從大規模資料中尋找規律、建立預測模型,並轉化為可解釋的生物學知識。

03

Structural & Molecular Biology
結構與分子生物學

We study the structures, dynamics, and interactions of proteins, nucleic acids, and other biological macromolecules to reveal the molecular mechanisms underlying biological function.

研究蛋白質、核酸與其他生物巨分子的結構、動態與交互作用,從分子尺度理解生命功能背後的作用機制。

04

Biotechnology & Biomedical Applications
生物科技與生醫應用

We translate fundamental discoveries into practical applications in drug discovery, precision medicine, antimicrobial resistance, protein engineering, plant biotechnology, diagnostics, and other emerging areas of biotechnology.

將基礎研究成果延伸至藥物開發、精準醫療、抗藥性、蛋白質工程、植物生物科技、疾病診斷及其他新興生物科技應用。